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MNT 1 > Exam 1 > Flashcards

Exam 1 Flashcards

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1
Q

What holds a pill together as a binder and could affect dissolution?

A

Excipients (can be a buffer, binder, filler, emulsion, preservative).

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2
Q

Pills should always be third-party tested. What should you, as a dietitian, never provide a customer with and what should you give them when providing medication information?

A

Never from a .com website. Must be from a .gov like NIH.gov

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3
Q

What is the stamp on a pill to ensure it is 3rd party-tested and liable?

A

USP

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4
Q

What is the absorption of drugs called?

A

Pharmacokinetics

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5
Q

Two ways a drug can be absorbed?

A

Passive or Facilitated diffusion

Active transport

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6
Q

What would increase the possibility for food-drug interactions?

A

Malabsorption due to celiacs, IBD, Crohns, etc

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7
Q

The pregnancy drug categories are?

A

A: Safe
B: Should be safe- has some safe studies but proceed with caution
C: Some research points to unsafe- probably should not take
D: Research points to not being safe and risks are possible- don’t take
X: DO NOT take- death and health issues have been proved

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8
Q

Described as the fraction of a drug that reaches the systemic circulation

A

Bioavailability

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9
Q

An osteoporosis drug that can be significantly decreased (60%) in bioavailability if taken with coffee or orange juice. Must withhold from food before consumption as food is stomach makes absorption negligible.

A

Boniva

If in tube feed…make sure to stop tube feeding before.

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10
Q

What does Grapefruit do to some medications?

A

Blocks the metabolism and transport- which would cause the drug to build up in the body.

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11
Q

What drugs decrease the absorption of calcium-rich foods over time?

A

Corticosteroids

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12
Q

Are PO drugs less or more bioavailable than IV-administered drugs? Why?

A

Less due to excipients. IV drugs have a much less dose because of this.

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13
Q

What should you never take with iron supplements?

A

Calcium foods or supplements! Eggs, bran, fiber-rich foods/supplements, high-phytate foods, coffee, or tea.

Also do not take with food- but if you get nausea then can take something small with it just not those above foods.

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14
Q

What is it called when a drug reacts with certain nutrients and binds together like cement?

A

Chelation

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15
Q

Describe Chelation and which nutrients cause it

A

Binding together in tube feed formula. Iron, calcium, zinc, and magnesium can react.

Never take antibiotics (Cipro) with a multivitamin and iron or calcium!

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16
Q

What does ASPEN stand for?

A

American Society of Parenteral and Enteral Nutrition

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17
Q

Rules for crushing up pills for PN and EN

A

Do not mix medications or crush up into PN bag- use another bag and IV for meds.

For EN- crush up drugs.

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18
Q

What pills should you never crush up in a EN tube feed?

A

Extended Release Pills!

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19
Q

What drugs interact with Vitamin K? Understand this process and describe it.

A

Coumadin/Warfarin are blood thinners that dosage depends on Vitamin K in diet. Patient should keep Vitamin K in diet consistent.

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20
Q

How Gastrointestinal pH plays a role in absorption?

A

Some medications work better under a lowerr pH… so take with food in this case.

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21
Q

With what drug should tube feeding (EN) stop 2 hours before and 2 hours prior?

A

Phenytoin

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22
Q

What two drugs rely highly on Albumin for active transport?

A

Warfarin/Coumadin and Phenytoin

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23
Q

What medications can impair B12 status/absorption?

A

Proton-pump inhibitors and GERD medications. Need that stomach acid to absorb B12

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24
Q

What drugs damage the epithelial brush border and other epithelial cells?

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A

Cancer treatment ( chemotheraputic agents), NSAIDS, long-term antibiotic use.

Damage the skin, mouth, and GI tract.

25
Effects of diuretics on nutrient excretion?
Diuretics like Lasix commonly excrete higher than normal amounts of sodium, potassium, magnesium, and chloride. Sodium and Potassium might be supplemented.. UNLESS the diuretic is a potassium saving drug.
26
What is the term for very low sodium?
Hyponatremia
27
Ace inhibitors and potassium-sparing diuretics together causes?
The combination of a potassium-sparing diuretic and an ACE inhibitor (decreases potassium excretion) increases the danger of hyperkalemia
28
Explain MAOIs nutrient-drug interactions
Monoamine Oxidase Inhibitors. Inhibit the breakdown of tyramine (from tyrosine AA). Increased tyramine causes increase in blood pressure.
29
What is the name of the corticosteroid that decreases sodium excretion and over-time can affect/decrease calcium levels.
Prednisone
30
List how food and drugs can interact:
Drug may inhibit the ability for proper nutrient absorption/utilization Nutrient may inhibit drug absorption or transportation Taste and Smell might be altered - Xerostomia (dry mouth) is common GI discomfort/distress can cause a decrease in appetite Can affect glucose levels
31
How Alcohol affects drug interactions
- drugs increase the toxicity of alcohol - inhibits gluconeogenesis- increased hypoglycemic state.
32
What drug blocks the breakdown of fat and causes oily diarrhea?
Orlistat (OTC- over the counter)
33
How do drugs affect glucose levels and give examples
- can inhibit or stimulate glucose uptake - Can increase insulin sensitivity - Corticosteroids (prednisone) cause an increase in gluconeogenesis
34
What drug excipient is used with sedation and explain
Propofol is used with sedation. The 10% lipid emulsion adds about 1.1 kcal/ml. So, patient is getting extra calories from fat from this medication.
35
IBW equation UBW% IBW%
women: 100 + (5lbs x inches over 60) men: 106 + (6lbs x inches over 60) UBW : current bw/ usual bw IBW: current bw/ibw
36
waist circumference risk factors
> 40 inch for men > 35 inch for women
37
waist to hip ratio risk factors
> 1.0 for men > 0.8 for women
38
Healthy BMI range
18.5-24.9
39
When is waist to hip not the best indicator?
when over 35 BMI or under 60 inches
40
Importance of mid-arm circumference?
Helps see disease state and malnutrition
41
Mifflin St. Jeor Equation variables:
Weight (kg), Height (cm), and Age
42
BMI equation
kg/m^2
43
Protein Requirements
0.8 g/kg 1.2-2.0g/kg in disease state (trauma, wounds, disease, metabolic stress) 10-35 % AMDR (acceptable macronutrient distribution range)
44
Other ways to estimate caloric needs:
kcal/kg ex: 20kcal/kg actual body weight if BMI > 50 then use kcal/ IBW - For critically ill patients on ventilation or EN/PN use IBW or admitted weight (whichever is lowest)
45
know these abbreviations: OT SLP CRT/RRT PT PA MD DO LCSW
Occupational therapist speech-language pathologist certified/registered respiratory therapist physical therapist physicians assistant doctor of medicine doctor of osteopathic medicine ( example would be psychiatrist or cardiologist) Licensed counselor social worker
46
Other abbreviations: TPN CPN PPN PN EN NPO PO NGT PEG G tube J tube ND tube NJ tube
Total Parenteral nutrition central parenteral nutrition peripheral parenteral nutrition parenteral nutrition enteral nutrition nothing by mouth by mouth nasogastric tube percutaneous endoscopic gastronomy gastronomy tube jejunostomy tube nasoduodenal nasojejunal tube
47
Screening Tool Abbreviations and Meanings: MUST MNA GNRI
- Malnutrition Universal Screening Tool - Mini Nutrition Assessment - Geriatric Nutritional Reference Index
48
Goal of Screenings
To identify if someone is malnourished or at risk and to identify if nutrition therapy is needed or a possible solution. - is INDIVIDUAL
49
MNT Definition
The assessment, nutrition diagnosis, interventions, monitoring, and evaluation for established disease * Individualized nutrition based treatment plan provided by a RDN
50
Deciphering Nutrition Care Priority- Categories
Hx (medical history) Dx ( diagnosis ) PO TPN PPN Wt loss BMI
51
High priority Dx
Acute or Chronic Renal failure GI or Head/Neck Cancer Burns Coma Ileus ( intestines not working right) Malnutrition/ FTT Pressure Ulcers/Wounds Dysphagia Sepsis Pulmonary Failure (ventilation) Transplantation Cystic Fibrosis Diabetes
52
Assessment includes
Collection of medical history, medications, diet history, lab values, anthropometrics, physical exam, social history
53
What is the IBW equation called?
Hamwi Equation - does NOT adjust for age or race
54
BMI calculation
pounds/inches/inches x 703
55
What is the standard for technologically figuring out body composition? Explain
Bioelectrical Impedance Low body fat and more muscle/water = resistance and impedance is low High body fat = high resistance and impedance
56
DEXA
Dual-Energy X-Rap Absorptiometry
57
How does inflammation affect blood glucose?
Increased insulin resistance and Hyperglycemia
58
Positive acute phase proteins
CRP (C-Reactive Protein) and Ferritin (iron storage)
59
Negative acute phase proteins
Transferrin, Albumin, and Pre-albumin

MNT 1 (4 decks)

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