Exam 1 Flashcards

1
Q

The word anatomy means?

A

Greek for “to cut apart”

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2
Q

Cytology ?

A

The study of cells

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3
Q

Gross anatomy is?

A

structures visible to the unaided eye

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4
Q

Metabolism

A

Various chemical reactions tht organisms carry out are collectively

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5
Q

Homeostasis?

A

Refers to an organism’s ability to regulate its internal environment despite changes in the external environment

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6
Q

A cell

A

Smallest structural unit that exhibits the characteristics of living things

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7
Q

The skeletal system

A

Provides support and protection as well as hemopoiesis

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8
Q

What is the function of cartilage located in the epiphyseal plate?

A

Site of bone elongation and growth

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9
Q

The knobby region at the end of long bone farthest

A

Distal epiphysis

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10
Q

The periosteum is anchored to the bone by collagen fibers called?

A

Perforating fibers

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11
Q

Intersistial growth of cartilage?

A

increases its length and occurs internally

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11
Q

An osteoclats looks like?

A

ruffled border and multipe nuclei

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12
Q

During appositional growth of cartilage, cells that produce the matrix?

A

Chondroblasts

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13
Q

What affects osteoblasts and osteoclasts activity ?

A

gravity, mechanical stress, blood calcium, calcitonin + parathyroid hormones

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14
Q

Endochondral ossification begins with ?

A

hyaline cartilage model

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15
Q

Steps of endochondral ossification ?

A
  1. Cartilage model develops
  2. Cartilage calcifies and a bone collar forms
  3. offification center forms in the diaphysis
  4. ossification centers form in the epiphyses
  5. Bone replaces cartilage
  6. Epiphyseal plates ossify
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16
Q

Mechanical stress is detected by?

A

Osteocytes - then to osteoblast to increase synthesis of osteoid

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17
Q

What hormone inhibits bone growth?

A

Parathyroid hormone

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18
Q

What vitman synthesised collagen?

A

Vitaman C

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19
Q

Rickets - overproduction and deficient calcification of osteoid tissue - lack of ?

A

Vitamin D

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20
Q

Calcitriol ?

A

stimulates absorption of calcium in small intestine

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21
Q

Which hormone has a significant effect on blood calcium levels?

A

Parathyroid hormone

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22
Q

components of skeletal systems?

A

Compact bone, trabecular bone, cartilage, ligaments

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23
Q

What is the process of bone repair?

A
  1. Fracture hematoma forms
  2. fibrocartilaginous callus forms
  3. Bony callus forms
  4. bone is remodeled
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24
OSteoporosis
Bones are porous and thin but bone composition is normal
25
Osteomalacia
Bone formed is poorly mineralized and soft. Deforms on weight bearing
26
Paget's disease
Excessive and haphazard bone deposit and resorption
27
Greenstick
An incomplete fracture of the bone without actual separation of the parts
28
Comminuted
Bone fragments into many pieces
29
Spiral fracture
Common sports fracture resulting from a twisting force
30
Epiphyseal plate
Area where bone longitudinal growth takes place
31
Inramembranous ossification
Bone develops from a fibrous membrane
32
Appoistional growth
The growth pattern of bone in which matrix is laid down on the surface
33
Epiphyseal line
The appearance of this structure signals the end of bone growth
34
Chondrocytes
The cells responsible for the early stages of endochondral ossification
35
Compact bone
Adapted to support weight and withstand torsion stresses
36
Yellow bone marrow contains ?
fat
37
Which cell secretes the matrix of bone?
Osteoblast
38
What tissue is the forerunner of long bones ?
Hyaline cartilage
39
what can a deficiency of growth hormone during bone formation cause?
Decreased epiphyseal plate activity
40
A fracture in the shaft of a bone would be a break in the
diaphysis
41
Ossification of the ends of long bones
is produced by secondary ossification centers
42
Which structure allows the diaphysis of the bone to increase in length until early childhood
Epiphyseal plate
43
Which of the following is the single most important stimulus for epiphyseal plate activity during infancy and childhood
growth hormone
44
The periosteum is secured to the underlying bone b
Perforating fibers (sharpeys)
45
The resilience of bone is thought to come from which of the following?
sacrificial bonds in or between collagen molecules
46
For intramembranous ossification to take place, which of the following is necessary?
Ossification centers form in the fibrous connective tissue membrane
47
The process of bones increasing in thickness?
Appositional growth
48
Bones are constantly undergoing resorption (breaking bone down) for various reasons. Which of the following cells accomplishes this process
Osteoclast
49
Which hormone increases osteoclast activity to release more calcium ions into the bloodstream
PTH
50
Wolff's law is concerned with
The thickness and shape of a bone being dependent on stresses placed upon it
51
Cranial bones develop?
within fibrous membranes
52
in humans, the effect of the hormone calcitonin is to
emporarily decrease blood calcium levels when administered in large doses
53
Cartilage grows in two ways, appositional and interstitial. What is appositional growth?
the secretion of new matrix against the external face of existing cartilage
54
Which of the following statements best describes interstitial growth of cartilage?
Chondrocytes in the lacunae divide and secrete matrix, allowing the cartilage to grow from within.
55
In the epiphyseal plate, cartilage grows
by pushing the epiphysis away from the diaphysis
56
Spongy bone contains
trabeculae
57
Ossification (Osteogenesis) is the process of
bone formation
58
Lengthwise, long bone growth during infancy and youth is exclusively through
interstitial growth of the epiphyseal plates
59
Growth of bones is controlled by a symphony of hormones. Which hormone is of greatest importance for bone growth during infancy and childhood?
growth hormone
60
In some cases, the epiphyseal plate of the long bones of children closes too early. What might be the cause?
elevated levels of sex hormones
61
Prevention of osteoporosis includes adequate intake of
Calcium and Vit D
62
What tissue forms the model of endochondral ossification
Cartilage
63
the pubic symphysis connects the two hip bones anteriorly and provides a little movement during childbirth. Choose the most appropriate tissue for this structure that is subjected to both pressure and stretch
fibrocartilage
64
structures that most directly provide nutrients and remove wastes from osteocytes in compact bone.
Canaliculi
65
When an osteoblast becomes completely surrounded by its own matrix secretions it is referred to as an
Osteocyte