Exam 1 Flashcards

(68 cards)

1
Q

All the DNA in a cell adds up to the cells

A

genome

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2
Q

the two types of genomes and differences

A

single DNA molecule -prokaryotes, circular
several DNA molecules- linear, eukaryotes

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3
Q

DNA molecules in a cell are packaged into

A

chromosomes

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4
Q

eukaryotic chromosomes consist of

A

chromatin

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5
Q

What does chromatin do

A

condenses to make chromosomes.
complexes of DNA and protein that condense during cell division

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6
Q

the chromosomes that are not sex chromosomes are called what

A

autosomes

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7
Q

what are the names of the short and long arm of chromosomes

A

short arm =p
long arm= q

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8
Q

where are centromeres located

A

mostly middle of chromosome but doesnt have to be

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9
Q

what is a centromere

A

where two chromatids are most closely attached- pinched site

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10
Q

each duplicated chromosome has 2

A

sister chromatids

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11
Q

how are sister chromatids attached- essentially how do they move around and not get damaged?

A

cohesion proteins called cohesin- like a zipper along chromosome

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12
Q

what does the kinetochore do

A

pulls the sister chromatids apart- hopefully equally. spindle microtubules attach to really pull them apart.

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13
Q

where do homologs exist

A

in somatic cells of diploid organisms

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14
Q

are homologs identical

A

no but they are similar

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15
Q

alleles in terms of homologs

A

chromosomes can carry different version of the same gene which is called an allele

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16
Q

sex determining chromosomes are not homologous but behave as

A

homologs in meiosis

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17
Q

when does mitosis occur in somatic cells

A

when
-organisms need to grow
-repair damage
-asexual reproduction

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18
Q

meiosis yields ___-_____ daughter cells that have ____ as many chromosomes as the parent cell

A

non identical
half

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19
Q

another name for mitosis

A

karyokinesis

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20
Q

what is mitosis in short

A

division of nuclei

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21
Q

what is cytokinesis in short

A

division of cytoplasm

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22
Q

do both mitosis and cytokinesis need to occur in a cell

A

no, mitosis always happens but cytokinesis doesnt always

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23
Q

gametes are produced by what

A

meiosis

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24
Q

can cells have different DNA content and cytoplasmic content

A

no they must have the same DNA content but can have differing cytoplasmic content.

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25
do all cells go through mitosis
no, once they become differentiated they lose the ability to divide
26
what phase of interphase replicates chromosomes
the s phase
27
what kind of cells have a cell wall
plant cells
28
where is rRNA synthesized
nucleolus
29
in prokaryotes where is the DNA since they do not have membrane bound organelles
nucleoid
30
what is the function of the endoplasmic reticulum
compartmentalizes cytoplasm increases surface area -Biochemical synthesis!
31
what do cells do in G0 phase
stay metabolically active but are not rapidly increasing in #(proliferative)
32
how to tell interphase and prophase apart
interphase does not have a distinct circle shape. prophase- centrioles not fully opposite, centromere not connected
33
How to tell prometaphase
chromosomes clearly double structured- not all but some are connected and not in the middle -centrioles opposite -spindle fibers are formed
34
how does the cytoskeleton attach to chromosomes
via kinetochores- attachment sites on centromere
35
what is an aster
array of short microtubules which extends from each centrosome
36
what are centrosomes composed of
2 centrioles
37
why is the mitotic spindle a target for cancer treatments
dynamic instability- some plants prevent microtubule assembly and some prevent disassembly
38
how to distinctly tell a cell is in metaphase
lined in the middle arms kind of hanging out at the end
39
how many chromosomes and sister chromatids are in metaphase
chromosomes- 46 sister chromatids-92
40
how many chromosomes and sister chromatids in anaphase
chromosomes- 92 sister chromatids- 0
41
1st step of checkpoints/cell cycle regulation
kinases adding phosphates to other proteins to regulate cell cycle
42
cyclin dependent kinases (CDKS) are activated by what
cyclin proteins
43
the ____ (initial fertilized egg) has a ____ chromosome number, one set from each ____
zygote, diploid, parent
44
what is the union of sperm and egg
fertilization
45
what does meiosis produce
gametes
46
what is aneuploidy
same number of chromosome sets but total chromosome number has changed by addition or deletion- down syndrome
47
what is aneuploidy caused by
nondisjunction
48
main difference between meiosis 1 and meiosis 2
meiosis -homologous chromosomes separate meiosis 2- sister chromatids separate
49
are alleles between sister chromatids exactly the same or different, what about homologous chromosomes
same , different
50
in mitosis are the cells genetically identical to parent cell or is that meiosis
yes- mitosis
51
what is synapsis
pairing of homologous chromosomes yields tetrads
52
what happens in prophase 1
homologous chromosomes synapse and cross over
53
where does independent assortment and the law of segregation
anaphase 1
54
what is formed in telophase 1
2 haploid cells- no homologs
55
what is crossing over and what kind of chromosomes participate
homologous chromosomes physically connect and exchange genetic information
56
what is independent assortment of chromosomes
each pair of chromosomes sorts maternal and paternal homologs into daughter cells independently of the other pairs
57
what does spermatogenesis yield
4 sperm cells
58
oogenesis yields what
1 oocyte and 2-3 polar bodies
59
what are the kinds of controlled matings
self-fertilization or cross-fertilization (pollination)
60
what is blending
red + white = pink
61
mendels law of segregation
from each parent you inherit only one of 2 alleles of each gene
62
genotype and phenotype ratios for a monohybrid cross
1:2:1 -genotype 3:1- phenotype
63
when in meiosis does segregation occur
anaphase 1
64
phenotypic ratio of dihybrid cross
9:3:3:1 for heterozygous
65
mendels law of independent assortment
non-homologous chromosomes and their alleles assort independently of each other
66
what is the product law
"and"- multiplication
67
what is the sum law
"or" -adding
68
equation for at least problems
1-(none)