Exam 1 Flashcards
HHealthcare Associated Infections (HAIs)
5% - 10% (approx. 2 million people) of hospitalized patients acquire 1 or more HAIs yearly 90,000 deaths annually $4.5 - $5.7 billion in excess healthcare costs annually 4 most prevalent cases responsible for 80% of cases: UTIs (35% and catheter related), surgical site infection (20% of cases but 1/3 of excess costs), bloodstream infections (15% majority are intravascular-catheter related) and pneumonia (usually ventilator-associated, 15% of cases, 25% of attributable mortality) Organisms in 70% of these infections are resistant to 1 or more antibiotics
NIOSH vs. OSHA
National Institute for Occupational Safety and Health (NIOSH) - makes rules Occupational Safety and Health Administration (OSHA) - enforces rules
Methylmethacrylate
Glue used for ortho cases OSHA 8 hrs avg 100 ppm (280 ppm max) Exposure for factory workers Causes respiratory (asthma), cutaneous, genitourinary, allergic sensitizer issues
Latex Allergy
70% rxn reported were healthcare workers Anesthesia sensitivity - 13-16% Can’t be reversed Caution for ppl with Spina Bifida (have severe latex allergy) History of Hay fever, Rhinitis, asthma, eczema Food allergies (avocado, kiwi, banana, chestnuts, stone fruit) Schedule elective surgery as first case of the day Post signs indicating “LATEX ALLERGY”
Radiation Hazards
Exposure: diagnostic radiographs, fluoroscopy, radiation therapy, PACU Lead aprons and shields Dosimeters - measure exposure Maintaining distance: E = 1/d2 Gonads = greatest sensitivity You can stand behind someone w/ the lead jacket and be okay
Laser Hazards
Risks include thermal burns, eye injury, electrical hazards, fire & explosion (O2) Plume contains viral DNA and toxic chemicals Need to wear high efficiency laser mask & special glasses If operating around the head w/ laser, you need to decrease FiO2
Major Reason for Error in Anesthesia Management
Fatigue - 64%
Requirements forTransmission of Infectious Agents
Source Stabile pathogen Adequate numbers Infectivity of agent Appropriate vector Portal of entry
Respiratory Transmission
Aerosolization Flu Measles Rhinovirus Tuberculosis Self Inoculation Rhinovirus Respiratory Syncital Virus
Influenza
Easily transmitted US 36k deaths, 200k hospitalizations Cells shed 5d
Rubeola & Rubella
Rubeola (aka Measles) Transmission: Aerosol Highly infective Maculopapular rash & Koplicks spots Fever and 3C’s - cough, coryza (runny nose), conjunctivitis Complications commons: M 1:1000, 30% immunosuppressed Rubella (German Measles) Causes misscarriages 1st trimester Birth defects or fetal defects Elective surgeries cancelled
Mumps (Epidemic parotitis)
Infection by airborne droplets Painful swelling salivary & parotid glands Symptoms not severe in children Most often children 5-9 YO
Respiratory Syncytial Virus (RSV)
Paramyxoviridae Most important / most common cause of lower respiratory disease in young 60% infants 100% 2-3 YO Infected by self-inoculation Prevalenet November-May Viable on surface for 6 hours Infected individual sheds virus for 7d Immunity not permanent Recurrent asthma symptoms in young kids for up to 6 mo
Rhinovirus
Most common viral infective agents in humans Causes common cold Transmission: self-inoculation and/or aerosolized particles Over 110 serologic virus types
Herpes Virus
Varicella-zoster (VZV) Chickenpox and herpes zoster (shingles) Communicability: 1-2 days before and last 5-6 days after HC workers >36 YO have VZV antibodies, 6.5% younger pop susceptible HSV 1 & 2 Type 1: Oral herpes Cytomegalovirus (CMV) Occurs during childhood 40-90% adults have antibodies Transmitted via direct contact Infection during pregnancy results in fetal infection 2.5%
Hepatitis B
- Prevalence HBV US is 3-5%
- Seoconversion up to 30%
- 5% develop chronic hepatitis which develops into cirrhosis and ESLD
- 1% develop fulminant hepatitis (>70% mortality)
- Transmission via sexual contact, shared needles/syringes, and perinatally
- HBV vaccines primary prevention strategy
Hepatitis C
Leading cause of chronic liver disease in US 9K new cases/yr Prevalence HCV in US ~ 3% 60% HCV infected patients will have chronic hepatitis / cirrhosis Seroconversion 1.8%
Leading cause of chronic liver disease in US
Hepatitis C
HIV
Seroconversion 0.3% percutaneous exposure, 0.1% mucous membrane exposure Increased risk associated with visible blood on device, deep injury, needle placed intravascular, terminal illness Since 1957, 57 documented cases of HCW acquiring HIV through exposure
Tuberculosis
Viable bacilli on airborne particles 1-5 microns 7-8 million become infected every year 8000 die each day Groups with high prevalence include: personal contacts with active TB, immigrants, alcoholics, homeless, IV users Protection: N95 mask, patient kept in neg. pressure rooms 3 neg. sputum acid fast bacillus smears to determine that patient is no longer infectious Non elective procedures done at end of day High efficiency filter (99.97% particles >0.3 microns) Filter put on expiratory port of circuit to protect machine
What fluids are and are not considered infectious?
Infectious Blood CSF Amniotic fluid Pleural Pericardial Peritoneal Synovial Inflammatory exudates (pus) Not Infectious Urine
Precautions for Patients with Multi-Drug Resistant Microorganisms
Methicillin-Resistant Staphylococcus Aureus (MRSA) - most common bug on surface of skin Vancomycin-Resistant Enterococci (VRE) Clostridium Difficile (cdiff) Hand washing (EtOH alone not effective) Yellow gown and gloves
Droplet Precautions
Wear a mask w/in 3 feet of patients with: Mumps German measles Streptococcus Meningococcal Spatial separation of 3 feet with other patients, keep curtains drawn
Disposal of Contaminated Materials
Linen: BLUE container Sharps: RED Reusable sterile gowns: GREEN Paper Goods: trash can
Cleaning Antiseptic Disinfectant Sterile Sterilization
Cleaning: Removal of Foreign Material Antiseptic: chemical germicide for use on living tissue Disinfectant: chemical germicide for use on non-living items Sterile: completely free of all microorganisms Sterilization: process that results in probability of microorganism survival on an item
Disinfection Levels
High-Level Disinfection: kills fungi, viruses, and vegetative bacteria (except endospores) Intermediate Level: kills fungi, non small or nonlipid viruses and bacteria (except endospores) Low-Level: Kills fungi, some viruses (lipid/medium sized) and bacteria (except TB, endospores)
Chlorine (Hypochlorite)
Most widely used of the chlorine disinfectants. Used on tables, floors, surfaces, equipment 1:100 - 1:1000 effective against HIV 1:5 - 1:10 effective against hepatitis 1:10 (5.25%) for blood spills
Sterilization
Steam (Autoclaving) Chemical (Gas, Liquid) Radiation Plasma
Autoclaving
Type of steam sterilization Quick, cheap, effective with no residues Kills everything (pressure & temp) Minimum times: 15 mins @ 121 C 10 mins @ 126 C 3.5 mins @ 134 C Confirmed by indicator strip inside the wrapped metal trays
Handling Preservative-Free Medications
Check label Use aseptic technique (alcohol swab) to rubber septum or neck of glass ampule Discard vial / ampule or syringe after use
Multidose Vials
Aseptic technique (alcohol swabs) Uncontaminated vial may be used until manufacturer’s expiration date
Betadine Allergy
People allergic to Betadine also often allergic to contrast dye and shellfish
Prevention of Intravascular Catheter-Related Infections
Catheter Selection Single lumen is best Antimicrobial or antiseptic impregnated CVC Insertion Subclavian v. carries a lower risk Barrier Precautions Catheter Site Dressing Transparent, semi-permeable polyurethane dressings permit continuous visual inspection of the catheter site
Surgical Subspecialties: Cardiovascular Cases
CABG: Coronary Artery Bypass Graft Valve Replacement Aortic Arch Dissection - longitudinal tear Aneurysms Congenital Defects Transplants
Surgical Subspecialties: CV Anesthetic Concerns
General Anesthesia Sternotomy Cardio-pulmonary bypass Invasive Monitoring ICU Transport Chest Tube Placement
Surgical Subspecialties: Thoracic Cases
Tumor Resection: Lumpectomy, wedge, lobe, pneumonectomy Lung Reduction Transplant Esophageal Resection Tracheal Resection Thoracoscopy Bronchoscopy (put a scope down the ETT, so you have to do a TIVA)
Surgical Subspecialties: Thoracic Concerns
General Anesthesia One-lung ventilation Sternotomy Positioning Invasive Monitoring ICU Transport Chest Tube Placement
Surgical Subspecialties: Neurological Cases
Intracranial (tumor, aneurysm/AVM - arteriovenous malformation, trauma/bleeding, craniectomy, VP shunt - ventricular-peritoneal Spinal - decompression/fusion, alteration/straightening Functional - DBS, Infusion pumps, generator changes
Surgical Subspecialties: Neurosurgery Anesthetic Concerns
General Anesthesia vs. Local Anesthetic vs. MAC Invasive Monitoring CBF Changes/Diuretics Hyperventilation Positioning Head Fixation (Mayfield) Paralysis Burst Suppression (slowing down all electrical activity in the brain while they operate on it - done with high dose Propofol infusion)