Exam 1 Flashcards

(71 cards)

0
Q

The category of genetics that has to do with inheritance

A

Classical

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1
Q

Categories of inheritance:

A

Classical
Molecular
Applied genetics

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2
Q

The category of genetics that has to do with figuring out what it was and how it functions

A

Molecular

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3
Q

The category of genetics that has to do with agriculture. Can be subdivided

A

Applied genetics

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4
Q

The most fundamental level of inheritance is:

A

The cellular level

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5
Q

Two types of cell division:

A
  1. Mitosis

2. Meiosis

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6
Q

A clonal process “sameness”. Mother cell divides and produces two identical daughter cells. Growth, repair.

A

Mitosis

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7
Q

Promotes variation
Designed to promote success
Objective to succeed. Wide range of variation.
Genetics plasticity**

A

Meiosis

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8
Q

Actual mitosis begins with ….

A

Prophase

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9
Q

…. beginning of mitotic division

A

Replication

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10
Q

Condensation begins; packaging method. Compact units.

Takes long DNA and packages it in compact that can move.

A

Prophase

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11
Q

Spindle is establish- involves the centriole dividing and migrates to either end of cell. Migrates to opposite side and radiate spindle fibers.

A

Prophase.

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12
Q

Last thing in prophase …

A

Nuclear membrane dissolves.

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13
Q

Causes the alignment of chromosomes in straight line

A

Metaphase

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14
Q

Sameness in :

A

-size
Shape
DNA content -total amt. present
Gene loci

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15
Q

Shape is determined by…

A

Position of centromere

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16
Q

Region of chromosome where copy and original are held together
Point of attachment for spindle fibers

A

Centromere

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17
Q

Not same =

A

Alleles

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18
Q

Late replication of centromere
Depolymerization of spindle fibers- drawn back to poles
Being pulled apart

A

Anaphase

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19
Q

Reversal of prophase
De condensation/unravel
Reformation of nuclear membrane

A

Telophase

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20
Q

In folding of plasma membrane
They meet in the middle and be come fused
Becomes 2 cells
Final event

A

Cytokinesis

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21
Q

Meiosis has 2 sequential divisions

A
  1. Reductional

2. Equational

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22
Q

Chromosomal ploid is reduced from diploid to haploid

2n - n

A

Reductional - bulk

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23
Q

Haploid to haploid

n -n

A

Equational

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24
5 subphases in prophase:
``` Leptonema Zygonema Pachynema Diplonema Diakinesis ```
25
A set of condensation of (chromomeres )
Leptonema/ leptotene
26
Beginning of synapsis
Zygonema
27
When synapse is complete | Key event: crossing over occurs but not always - exchange b/n non sister chromatids
Pachynema
28
Pairs homologs physically
Synapsis
29
What holds sister chromatids together is..
Synaptonemal complex
30
Synapsed pair is called a
Bivalent
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Key event: synapse is complete | Crossing over can occur b/n non sister chromatids
Pachynema
32
Centromeric "repulsion" -not truly repulsion Begin to see chiasmata Seperation of homologs
Diplonema
33
Key: terminalization of chiasmata / chasma Cross points pushed Maximum condensation
Diakinesis
34
5 postulates from Mendel
1. Unit factor in pairs - occurs in pairs 2. One unit factor can be dominate to the other 3. In reproduction each parent contributes one and only one unit factor 4. Whichever unit factor contributes randomly determined - random segregation 5. Independent assortment of the alleles/unit factor of 1 locus relative to 2nd locus- random segregation occur at two independent loci simultaneously.
35
Modifiers (2)
1. Expression allele- more than simple dominance | 2. Number of alleles- more than 2 alleles at a given locus
36
``` How expressed (alleles) How alleles are expressed? ```
``` A. Codominance B. Epistasis C. Lethality D. Presence of multiallelic loci E. Environmental ```
37
Alleles equally expressed (blending) | Both alleles expressed
Codominance
38
Involves 2 or more independent loci | - the alleles of one locus will either mask or modify how the alleles of the second locus
Epistasis
39
Lethality
? Refer to notes
40
An example is ABO blood type | Refer to notes
Presence of multiallelic loci
41
Expressed in a particular way always- refer to notes 1. External environment influence 2. Internal environmental change/influence- common factors-hormonal a. Sex influence - reversals of dominance in the sexes b. Sex limited more absolute/variation in the expression, limited to one sex.
Environmental
42
Observation that one locus may influence multiple characters
Pleitropy
43
Reproductive output
Fecundity
44
The sudden reappearance of an ancestral phenotype
Atavism
45
For each locus the following will be true:
1. Additive and non additive alleles 2. Each additive contributes equally 3. Phenotype is determined solely by the umber of additive alleles
46
Types of linkage
Complete Incomplete De linked
47
No crossing over b/n the loci (If no x-o then you get big with big and small with small) All parental
1. Complete linkage
48
Crossing over occurs but only some of the time X-O occurs some of the time Parental > 50% Recombs. < 50%
2. Incomplete
49
Crossing over occurs all the time 50% parentals and 50% recombs X-O all the time
De linked( no formal name)
50
How many bacteria reproduce?
Binary fission
51
The most successful organism and oldest
Bacteria
52
Characteristics of bacteria:
1. Largely haploid-present in one copy only 2. Very rapid generation time 3. Form very large populations 4. Rely on mutations- sudden, random heritable change
53
Consequences of mutations:
1. Neutral- doesn't change the function 2. Deleterious - bad( lethal) 3. Beneficial
54
Bacterial recombination
Allows them to gain variation
55
Uptake of free DNA
Transformation
56
Virally mediated transfers
Transduction
57
Viruses that target bacteria
Bacteriophage
58
Two types of bacteriophage
1. Intemperate | 2. Temporate
59
Lytic only
Intemperate
60
Lyrics or lysogenic
Temperate
61
Transduction is a ...
Virally mediated process | Requires a series of mistakes
62
Types of transduction
1. Specialized 2. Generalized 3. Conjugation
63
This type of transduction where prophage occurs at one place only -limited number of genes transferred
Specialized
64
This type of transduction where prophage insertion is random | Where all genes have equal frequency of transfer.
Generalized
65
Involves Genetic transfers from a donor bacterium to a recipient -found only in some bacteria
Conjugation
66
Extra chromosomal DNA Sometimes called "mini chromosomes" Circular and double stranded
Plasmid
67
Extra chromo | And autonomous
Plasmid ( again) | Mini chromosome
68
Separate from main chromosome and replicate on their own schedule - independent
Autonomous
69
Can occur as autonomous | Can also occur as integrated state - becomes part of the bacteria chromosome
Episome
70
Partial diplody
Merozygous