Exam 1 Flashcards

(184 cards)

1
Q

basic vital signs

A

blood pressure, pulse, respiratory rate, temperature, pulse oximetry (and now pain)

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2
Q

when normal signs do not = hemodynamically stable state

A

acute blood and fluid loss
serious illness in infants
meds blunt response (elderly)

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3
Q

normal (adult) vital signs

A

BP: 90-120 / 60-80
HR: 60-100bpm
RR: 12-20

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4
Q

classification of blood pressure

A

normal: <120 and <80
pre-HNT: 120-139 or 80-89
HNT, stage 1: 140-159 or 90-100
HNT, stage 2: >160 or >100

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5
Q

children vitals - trends

A

BP is lower (80-110 systolic)
HR (80-100) and RR (15-30) higher

Note: infants even more dramatic

  • BP: 70-90 systolic
  • HR: 100-150
  • RR: 25-50
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6
Q

causes of tachypnea

A
Pneumonia
Asthma Exacerbation
Heart failure
Pulmonary embolism
Anxiety
Drug intoxication
Metabolic Acidosis
Lung Trauma, rib fx
Pain
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7
Q

causes of bradypnea

A

Alcohol or drug overdose
Sedative or hypnotic medications
Impending respiratory failure
OSA/ Sleep apnea

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8
Q

best way to measure HR

A

apical rate (bottom left of heart) for 60 seconds

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9
Q

causes of tachycardia

A
Fluid or blood loss
Anxiety
Pain
Sepsis
Allergic Reaction
Fever
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10
Q

causes of bradycardia

A

Medications
Drugs
Brain injury
Heart blocks

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11
Q

temperature

A

most accurate = rectal

oral is 0.6 C (1 F) lower than rectal

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12
Q

fever

A

not an illness - a clinical response (that of uncompfortable)

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13
Q

temperature: C to F conversions

A

37 = 98.6 F
38 C = 100.4 F
39 C = 102.2 F
40 C = 104 F

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14
Q

pulse oximetry

A

measures arterial hemoglobin (hgb) saturation

limits:

  • hypoperfusion (below 80 mmHg systolic)
  • hypothermia
  • anemia: if Hct is
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15
Q

causes of low oxygenation

A

elevation
hypoventilation
probe not on correctly (see waveform)
V-Q mismatch: atelectasis, pneumonia, PE, ARDS, CHF

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16
Q

AHA BP technique

A

seated for 5 min w/ arm supported at heart level

appropriate cuff size (bladder nearly or completely encircle arm)

no smoking or caffeine for 30 min

two or more readings separated by 2 min should be average (more taken if differ by >5mmHg)

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17
Q

blood pressure cuff - repercussions of improper fit

A

too narrow: overestimates BP

too wide: underestimates BP

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18
Q

causes of hypotension

A
Acute blood or fluid loss
Sepsis
Anaphylaxis
Medications, drug overdoses
Fit people
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19
Q

causes of hypertension

A
Medication non-compliance
Pain, anxiety (white coat syndrome)
Poor cuff size
Medical History: HTN, CAD, DM, renal insufficiency, 
Drugs :  cocaine, meth, decongestant
MAOI use with tyramine containing food (old anti-depressent)
Pheochromocytoma (tumor)
Renal Stenosis
“Hypertensive Emergencies”
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20
Q

hypertensive urgency

A

symptomatic elevated BP without End Organ Damage

BP of >180/120 used to suggest treatment

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21
Q

hypertensive emergency

A

elevated BP with End Organ Damage, such as ARF, MI, CHF, SAH (subarachnoid hemorrhage), stroke, etc.

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22
Q

possible result of HTN emergency

A

Pulmonary Edema - crackles in lungs

Aortic dissection – ripping tearing CP to back

ACS (Acute Coronary Syndrome) – CP, EKG changes, elevated trop

Preeclampsia – protein in urine, HA, edema

Hypertensive Encephalopathy – mental status changes

Subarachnoid Hemorrhage – sudden, worst ever HA

Ischemic Stroke – neuro deficits

Renal Failure – decreased UOP, high creatinine

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23
Q

HTN emergency workup

A

guided by symptoms

EKG : ST segment changes, suggesting ischemia
UA : Hematuria, casts, proteinuria suggesting renal impairment
CXR : pulmonary edema c/w CHF;
Widened Mediastinum c/w Aortic dissection

Other studies:
Electrolytes: elevated Cr, hyperkalemia
Head CT:  if concerned for stroke
Upreg:  preeclampsia 
Utox
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24
Q

HTN emergency - management

A

Immediate but careful reduction in BP - lower slowly (except aortic dissection and ischemic stroke)

Reduce MAP by no more than 10-20% in 1st hour

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25
calculation MAP
MAP = [(2 x diastolic) + systolic] / 3 Usual 70-110 MAP of about 60 is needed to perfuse the coronary arteries, brain, kidneys
26
hypertensive urgency - treatment
Labetolol 200 mg po Captopril 25 mg po Nitroglycerin tab or spray Clonidine .1-.2 mg PO Note: clonidine drops BP quickly but can can cause quick rebound to HNT - ask when not to use
27
medications for HNT - general word roots
- olols: beta blockers (block receptors for epi / adrenaline so heart beats slower and less intensely, which vessels dilate) - prils: ACE inhibitors (ACE converts Ang I to Ang II, which constricts muscles around blood vessels) - zides: diuretics (inc. salt in urine which takes H20 with it, decreasing vol. of fluid in vessels)
28
severe HTN (asymptomatic)
Treat if BP>180-200/110-120 Diuretics: HCTZ, 25 mg PO qd - uncomplicated HTN B-blocker : metoprolol 50mg PO BID - angina, Post MI, migraines, SVT (supraventricular tachycardia) ACE Inhibitor: Lisinopril 10mg PO qd - if HF, renal disease, stroke, DM - starting medications
29
pain
an unpleasant sensory and emotional experience with actual or potential tissue damage or described in terms of such damage.
30
oligoanalgesia
inadequate pain control
31
clinical features of pain
physiologic: inc. BP, inc. HR, tachypnea, nausea, diaphoresis (sweating), and skin color changes (pale or flushed) behavioral: crying, yelling, cursing, withdraw, posturing,
32
pain and vital signs
vital signs are no a reliable guide to pain relief
33
pain assessment - pneumonic
``` O: onset P: provoking factors (what makes worse or better) Q: quality (sharp, dull, constant) R: radiation (where it moves) S: severity T: time course ```
34
results of poor pain management
``` Unnecessary suffering Delayed healing Altered immune response Altered stress response Development of chronic pain ```
35
non-pharmacologic treatment for pain
heat/cold immobilization/elevation explanation/reassurance distraction
36
narcotics - proper use
treatment of moderate to severe pain | - best known narcotics are opiates (derived form opium)
37
narcotics - things to consider when selecting
``` route of administration - surgery: NPO suitable initial dose frequency of administration side effects use in- vs. out-patient ```
38
routes for pain medications
IV: easy to titrate, rapid onset of action, no delayed respiratory depression IM: intramuscular - not common in ER SQ: subcutaneous PO: oral - slow onset, NPO (?), N/V IO: interosseous - into bone marrow (often tibia), fast onset, good option with collapsed peripheral veins or edema; can deliver all meds! IN: intranasal -pain control, seizures, palliative care, opiate OD, good for kids, limited on dose (max 1 ml q nostril) PR: per rectal
39
conversion: pounds to KGs
lbs/2.2 = kgs lbs/2 - 10%(lbs/2) - kgs
40
conversion: KGs to pounds
kg x 2.2 = lbs kgx2 + 10%(kgx2) = lbs
41
analgesic
pain killer
42
narcotics / opioids - administration route for specific meds
PO: oxycodone, hydrocodone, codeine, methadone, tramadol Common IV: hydromorphone, fentanyl, morphine - Note that most of these meds can be given IM and PO also
43
side effects of opioids
``` Nausea and vomiting (25%) Constipation Urinary retention Respiratory depression (more pronounced in IV) Sedation Miosis (pupil restriction) Pruritis (itching) Antitussive (rid cough), antidiarrheal ```
44
acute opiate withdrawal - symptoms
Mydriasis (pupil dilation), yawning, increased bowel sounds, piloerection (goose bumps), restlessness, plus flu like symptoms: - n/v/d, abdominal cramping - rhinorrhea, lacrimation (tears) - myalgias, arthralgies, piloerection
45
acute opiate withdrawal - treatment
symptom management may offer Clonidine (1-3 mg TID prn)
46
Janka's PO pain med regimen
1. Motrin 600-800 TID and/or Tylenol 1 g TID-QID - can take OTC 2. Norco 5/325 or Percocet 5/325 1 tab QID prn, w/ colace, prune juice, metamucil; driving precautions 3. Rarely –Dilaudid 2 mg QID prn +/- NSAIDs - may be missing something if need to prescribe in ER
47
prescribed opiate abuse in CO
CO has 2nd highest rate of prescription painkiller abuse in nation coloradopdmp.org - website that lists all controlled substances a person has been prescribed
48
drug seeking behavior - red flags
- Out of town - Lost or stolen prescription - ED visits on weekends or night - Frequent ED visits (no follow up appointments) - Unusual knowledge of controlled substances - Request a specific drug - Long list of drugs they are allergic to - Do not permit a physical exam - Create a sense of urgency - Common complaints: dental pain, back pain
49
drug speaking behavior - management
Attempt to contact patient’s physician to confirm history Confirm patient has provided a copy of a photo ID and SSN Check the CO PDMP Talk to the the patient about your concerns
50
procedural sedation
pharmacological state of profound sedation with maintenance of all protective reflexes, spontaneous ventilation is adequate and airway is maintained
51
procedural sedation - levels
Minimal: mild anxiolysis (antianxiety) or pain control - ventilation, CV fx maintained; no cardiac monitoring needed Moderate ("conscious sedation"): pt is sleepy but arousable to voice or light touch (eyes closed) - GOAL FOR MOST ED procedural sedation Deep: requires painful stimuli to evoke a purposeful response - may require assistance to maintain airway, CV fx usually maintained
52
general anesthesia
Patients cannot maintain airway or airway reflexes Requires support of airway, breathing and cardiovascular functions NOT COMMON IN ER
53
procedural sedation - patient evaluation
History: last meal, allergies, substance use and abuse, major organ system abnormalities, previous anesthesia use and complications. Physical Exam: airway, heart, lungs Fasting preferred Patients with severe cardiac or pulmonary problems are poor candidates
54
procedural sedation - monitoring
Hemodynamic: cardiac monitor, auto BP cuff ( q 5 min) Respiratory/Airway: continuous pulse oximetry, suction equipment, supplemental O2, bag valve mask, end tidal CO2? Level of consciousness IV access, reversal agents, COR cart Provider skill set: necessary if problems occur
55
predictors of difficult airway
Obesity with short neck Reduced neck movement Reduced TMJ movement Receding mandible Mallampati grading system scale: assess ease of intubation if needed
56
Mallampati grading system scale
Assess ease of intubation if needed: - class 1: soft pallet, uvula, pillars visible - class 2: soft palate and uvula visible - class 3: soft palate and base of uvula - class 4: only hard palate visible
57
NSAIDS - mechanism
Potent inflammatory action occurs through inhibition of prostaglandin synthesis at wound site by blocking COX enzymes (reducing inflammation, pain and fever) - aka, inhibits COX-1 and COX-2 Note: also upsets GI (ulcers) and causes bleeding (anti-coag) since prostaglandins protect stomach and help with coagulation
58
discharge criteria (from ER)
``` Stable vital signs 30 min) No evidence of respiratory distress Minimal nausea (tolerate PO fluids) Ambulation equal to pre-procedure Alert, oriented, and able to retain discharge instructions Responsible person to watch patient ```
59
wound management - history questions
``` mechanism of injury - how happen (bite, blunt, penetrating) - potential for infection - how long ago tetanus status, meds, allergies, co-morbidities foreign body possibility - sensation of FB if hand injury: dominant hand, type of work ```
60
wound management - physical exam
document neurovascular function (injury to tendons, nerves, joint capsule, blood vessels) - BEFORE anesthesia!
61
wound closure and suturing
typically do not close >8 hrs after injury (primary intention) face/scalp/neck: up to 24 hours
62
bite wounds - animal or person
typically do no close (unless gaping or for cosmetic) ABX: Augmentin must call animal control (ask about rabies)
63
wound management - anticipatory guidance
begin to wash wound 1-2 days (impervious t water after 24-48 hrs) remodeling lasts for up to 6 months (cannot predict scar at time of sutureing) sunscreen will help scarring
64
mechanism of injury - 3 types
shear: simple dividing of tissue (sharp glass, knife); low energy force - heal with good result Compression: crushes skin against bone (stellate laceration) - baseball bat, windshield Tension: flap type laceration - high energy forces with surrounding tissue devitalized and prone to infection
65
tetanus prophylaxis
Update if last Tetanus was > 10 years ago If very dirty or high risk, consider updating if last dose 5-10 years ago Tdap if adult; DTaP if pediatric
66
infection prevention
irrigation: high volume good debridement: cut out fatty tissue and irregular edges blood supply: higher = less infection prep: clean would
67
prophylactic antibiotics in wound management
healthy patient do not require Use in specific situations: - wound in mouth, genitals, feet (w/ saliva, feces, vaginal secretions) - delayed presentation - immunosupressed pt (DM, steroids, renal insufficiency) - bites of any kind - cartilage (poor blood supply) or joints - valvular heart disease - contaminated woulds with soil and organic materials (wood)
68
rabies - most likely transmitters
wildlife (92% exposures): raccoons, skunks, bats, foxes) domestic animals (8%): cats, dogs internationally: stray dogs never: small rodents (squirrels, chipmunks, rats, mice, etc.)
69
principles of wound care
inspect and examine prep (baby soap and H2O) and anesthesia wash/irrigate/debride - note: clip, do not shave hair hemostasis (stop blood) - if pulsing, explore arterial injury (if close, hematoma will occur) exploration - explore through full ROM in bloodless field (use instruments) closure (type, material used) dressing care instructions
70
local anesthesia for wound care
Drug classes: amides - most common class: lidocaine (1-2 hrs), bupivicaine (4-6 hrs) Drug class: esters - cocaine, procaine, tetracaine (eye drops) Epinephrine: often added to local anesthetic
71
epinephrine - why added to local anesthetics
provides hemostasis longer duration of action slows systemic absorption thus decreasing potential toxicity can use “more” (but may not need to) Note: never use on fingers, toes, penis, nose, or ears (extremities)
72
epinephrine - where not to use
fingers, toes, penis, nose, or ears (extremities) | - can block only circulation and cut off blood
73
ways to limit pain on injection of local anesthetic
Anesthetic is acidic (low pH) = burns! Sodium bicarbonate 1:10 (shelf life 1 week) Warming the solution Size of the needle (smaller) Injecting slowly Use of a topical anesthetic Ice on wound (especially helpful in kids)
74
wound irrigation
volume is key: more is better (min: 250cc, ave: 1 liter, 100cc/cm of wound length) ``` moderate pressure (except loose tissue = low pressure) - 18 gauge IV cath w/ 30-60 cc syringe - can use pulse evac if dirty ``` Do not irrigate puncture wounds - SOAK use isotonic solution (saline) or tap water
75
types of wound closure
primary intention secondary intention tertiary intention
76
primary intention
surgical repair with initial reapproximation of tissue layers typically do not close >8 hrs after injury face/scalp/neck: up to 24 hours
77
secondary intention
epithelialization and growth from base used in ulcerations, abscess cavities, avulsions, punctures, bite wounds also used in wounds >8 hrs since injury
78
tertiary intention
delayed primary closure - surgical closure in 3-5 days after injury (only if no signs of infection) used of high velocity wounds, contaminated wounds, old wounds, stab wounds will lessen scarring and heal faster
79
terms for describing layers of skin - how deep wound is
``` epidermis - outermost dermis subcutaneous tissue (hypodermis) superficial fascia muscle layer deep fascia ```
80
prepping wound - hair removal / debridement
after cleaning (baby soap and H20) - clip, do not shave, hair - never clip eye lashes or brows Debridement (all devitalized or necrotic tissue should be removed) - improves vascularity - reduces infection
81
sutures - types, size, needle
absorbable: vicryl, chromic, gut non-absorbable: ethilon, prolene, silk size: inverse relationship (6.0 smaller than 2.0) needle: reverse cutting needed used in ER (allows smooth, atraumatic penetration of touch skin and fascia) - tapered needles used on soft tissue (or when smallest hole is needed)
82
absorbable sutures - tensile strength and time to dissolve
Vicryl: has 2-4 weeks of tensile strength, can take 2+ months to dissolve Plain Gut: 7-10 days of tensile strength; up to 90 d. to absorb Fast Absorbing Gut: 5-7 days of strength, absorbs in 3-4 weeks
83
suture sizes for different areas of body
face: 6-0 trunk: 3-0, 4-0 extremities: 4-0 - 5-0 on hands, toes scalp: 4-0 (or staples)
84
alternatives to sutures
staples: good for scalp steri strips: older people with fragile skin, kids, used to anchor would on fragile skin dermabond: glue (needleless wound repair) - do not use deep - best used on low tension wounds (avoid hands, feet, joints) - do not use on places requiring frequent washing - DO NOT USE topical antibiotics after closure
85
goals of suturing
minimize tension, evert edges, symmetrical alignment, good wound prep, homeostasis to allow full visualization of injury
86
wound care - what to tell patients
apply topical ABX ointment after lac repair and BID for 3-5 days (except Durabond) dressing left on for 24 hours; after that removed and left open to air clean wound: 50-50% H20 and water around wound edges or baby soap and H20 no soaking (swimming or hot tub) timing of suture removal (if applicable) signs of infection avoid sun exposure (sunscreen for 6 mo)
87
wound care - special concerns
``` Lip: vermillion border Oral: thru and thru Hand lacerations: FB, joint/tendon Eyelid lacerations: lacrimal system Nose: septal hematoma Ear: dressing is key Puncture wounds: pseudomonas Hand lacs: fight bite Cheek lacs: facial nerve ```
88
puncture wounds
do not close: heal to secondary intention plantar wounds (bottom of foot): tx with Cipro to cover for pseudomonas (esp if went through shoe) remove FB soak - do not aggressively irrigate
89
hand lacerations - special considerations
examine in position of injury and through full ROM (in bloodless field) consider flight bite x-ray for foreign body PE: motor and sensory distally, perfusion/cap refill - tendon involvement = referral
90
ear lacerations - special considerations
use small (6-0) non absorbable sutures to close skin cartilage only approximated dressing is key: form into ear crevasses so no blood accumulation and distortion
91
lip lacerations - special considerations
look for intraoral / thru and thru look for dental injury throw 1st stitch to approximate vermillion border (if involved) if not, begin on mucosal aspect then repair orbicularis oris ABX: PCN or clindamycin
92
eyelid lacerations - special considerations
when to refer: - inner surface of lid - lid margins - lacrimal duct involvement (plastics referral) - ptosis involvement (eyelid) - tarsal plate involvement (on each lid - muscle attachment)
93
nasal laceration
look for (and drain) septal hematoma - bloody pouch align skin surrounding nasal canals mucosal involvement: close with absorbable
94
facial lacerations
parotid gland: must ensure duct potency into oropharynx facial nerve: motor control of most of muscles of facial expression; taste to anterior 2/3 of tongue
95
suture removal recommendations
``` Face: 3-5 days Scalp: 7-10 days Hands: 7-10 days Feet: 7-10 days Extremities: 7-14 days (joints) Trunk: 7-10 days ``` note: leaving sutures in too long = scar
96
lacerations - when to refer
``` Patient request Foreign bodies Deep Structure involvement Time constraints Eye lid considerations Level of comfort ```
97
foreign bodies
x-ray finds glass, metal, gravel >2mm if pt feels FB sensation, take good look organic material (soil, wood, clay) more likely to become infected
98
regional blocks: advantages over infiltration
``` No tissue distortion Avoids infiltrating highly sensitive areas (palm) Longer duration of anesthesia Smaller amount of anesthetic needed Abrasion cleaning Fracture analgesia ```
99
regional blocks (or any anesthesia) - precautions
use sterile technique - alcohol swab anesthetic you are using (if already opened) - prep area before injecting
100
regional blocks for facial anesthesia
supraorbital nerve: whole forehead supratrochlear nerve (side of nose) infraorbital nerve: under eye to top of lip mental nerve: bottom lip and chin Note: all line up with pupil Note: rub tissue following injection to spread anesthesia
101
supraorbital nerve block
blocks forehead Procedure: inject into SQ space just superior to eyebrow in line with pupil to medial brow
102
infraorbital nerve block
blocks lower eye lid, medial check, side of nose, upper lip Procedure: inject mucosa above first maxillary pre-molar (tooth behind canine); angle up towards infraorbital notch under eye
103
mental nerve block
blocks labial mucosa, gingiva, and lower lip down chin Procedure: inject into mucosal fold at canine/first premolar
104
abscesses
difficult to get good anesthesia use hemostat and Q-tios to get pus out use packing to keep wound open for drainage (remove in 48 hours)
105
suturing - general tips
facial sutures: 2-3mm from wound edge, 3-5 mm apart Other body parts: 3-4 mm form wound edge, 5-10 mm apart Note: always begin suturing distal to you and suture towards you
106
simple interrupted stitch
technique: gather more tissue at base than at surface; eversion key; enter at 90 degree angle - # of ties = size of material when used: standard wound closure (low tension and not too deep)
107
subcutaneous / buried stitch
technique: enter at mid dermis and exit at dermal/epidermal junction; then enter dermal/epidermal junction and exit mid dermis - avoid placing in adipose tissue - know it deep (bottom of stitch) when used: gaping wounds
108
running suture
technique: simple interrupted at one end and tie knot (only cut short end), continue stitching along wound. - to tie off: leave loop of suture and tie as if tying with two ends (pull loop through) when used: in hurry with long, strait wound
109
horizontal mattress
technique: take big bite (1 cm from edge) and out other side. On same size, go down 1 cm and re-enter, taking another big bite (tie off on original entering side) - add simple interrupted stitches and, when done, pull out horizontal mattress when used: temporary placement w/ high tension repair to approximate edges; wounds with increased tension (fascia and over joints)
110
vertical mattress
technique: take big bite (1 cm from wound edge); reverse needle and go back through 1-2 mm from wound edge) - tie off on original side - typically continue with these same sutures along wound (may add few simple interrupted) - risk: too much tension = strangulation, maceration, infection when used: excess, lax skin (all in one - avoid a layered closure)
111
chest pain differential - cardiac
angina/MI aortic dissection (ripping pain through back) pericarditis/tamponade
112
chest pain differential - pulmonary
pneumonia/bronchitis pulmonary embolism pleurisy (inflammation of pleura - membranes of pleural cavity) pneumothorax/pneumomediastinum
113
chest pain differential - neuro/psych
Thoracic outlet syndrome (compression of nerves, arteries, or veins form lower neck to armpit) Herpes Zoster (shingles) Anxiety Radiculopathy (pinched or compressed nerves)
114
chest pain differential - MSK
costochondritis rib trauma rib Strain/ coughing - nonspecific
115
chest pain differential - GI
``` PUD (peptic ulcer disease)/gastritis cholecystitis (gallbladder) pancreatitis (radiates to back / alcoholic) peritonitis GERD/spasm esophageal rupture ```
116
chest pain differential - life-threatening conditions
``` Ischemia/ MI Aortic Dissection Pericardial Tamponade Pulmonary Embolism Esophageal Rupture ```
117
Chest pain - history / initial evaluation
ABC's (airway, breathing, circulation) History: associated sxs, medications, tx w/ meds, similar or previous episodes, recent trauma Pain characteristics (OPQRST)
118
Chest pain - physical exam
Pulmonary: - chest wall tenderness (MI, MSK) - rales (LV dysfunction, pneumothorax) Cardiac: - new murmur - Hamman's crunch Vascular: - carotid or femoral bruits - equal pulses Abdominal: - tenderness (cholecystitis, pancreatitis, etc.) Neuro: - AMS (altered mental status) - focal defects Derm: - vesicular rash (herpes zoster)
119
MI - characteristics on physical exam
chest pain to palpation (15%)
120
Hammans Crunch
heard on cardiac exam (w/ stethoscope) - crunching, rasping sound, synchronous with the heartbeat; heard over the precordium; produced by the heart beating against air-filled tissues. occurs with: pneumediastinum/pneumopericardium or esophageal rupture
121
cardiac risk factors - non modifiable
family hx gender (male) age (>45 male, >55 female) Note: be sure to ask about in hx, but although predictive of CAD in asymptomatic pts, poor predictor of AMI in ED
122
cardiac risk factors - modifiable (7 major)
``` HTN Smoking Hyperlipidemia Diabetes Obesity (cocaine) ``` Note: be sure to ask about in hx, but although predictive of CAD in asymptomatic pts, poor predictor of AMI in ED
123
Acute Coronary Syndrome (ACS)
Ranges from angina to MI - Occluded vessels can cause anginal pain with exertion (relieve with rest or NTG - nitroglycerin) - Plaque rupture can lead to total vessel occlusion/ Acute Myocardial Infarction - spectrum of clinical presentations Range: Stable Angina, Unstable Angina, NSTEMI, STEMI
124
vessel changes with coronary syndrome
plaque grown into vessel walls (not build up on inside of lumen) - so, plaque rupture is more likely to cause MI than stenosis
125
classical MI symptoms
``` substernal chest pain/pressure diaphoresis (sweating) nausea dyspnea (SOB) radiation to arm/jaw exertional ``` Lasting <2min or >24 hours is less likely to be ischemic
126
atypical MI symptoms
``` palpitations nausea SOB epigastric pain weakness fatigue ``` more common in women and diabetics; up to 50% of people with unstable angina may have atypical sxs and no chest pain
127
ACS - 4 sxs that are specific
Diaphoresis Vomiting (not nausea) Exertional chest pain Radiating pain to the back or right arm Note: just good to know this (possibly not tested)
128
stable angina
predictable pattern of chest pain/pressure/squeezing that occurs with exertion and relieved with rest or Nitroglycerin - lasts 5-15 min - occurs in known CAD - normal condition (stable) Note: PE, labs, CXR, EKG all normal in stable angina
129
unstable angina
new onset, change in severity, duration, frequency of the normal angina Note: PE, labs, CXR, EKG all normal in unstable angina
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NSTEMI (non-ST elevation MI)
worsening or changing symptoms, with myocardial damage | - see troponin elevation
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STEMI (ST elevation MI)
worsening or changing symptoms, with myocardial damage | - see troponin elevation and EKG changes
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chest pain: diagnostic tests
EKG: perform w/in 10 min of arrival (normal does not guarantee no MI) CXR: heart size, pneumomediastinum, pulm. congestion, free air) Labs: troponin, LFTs/lipase, D dimer, CBC, BMP Additional studies: - chest CT or V/Q scan: r/o PE - abd CT: r/o aortic dissection - cardiac US/echo: heart failure
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EKG changes indicative of MI
T wave inversion ST elevation Significant Q waves
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risks for cholecystitis - 4 Fs
forty fat female fertile
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D dimer
a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis (fibrin degradation product) - helps to dx or rule out thrombosis (blood clot) or dx DIC (disseminated intravascular coagulation)
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cardiac markers
troponin: rises w/in 1.5-3 hrs of injury (for acute MI) - 3 hour repeat troponin to r/o acute MI or risk stratify CK-MB, myoglobin: not relevant in ED
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troponin v. stress test
troponin are for acute MI stress tests are for CAD
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present to ED w/ chest pain - initial treatment and medications Note: there are algorithms for this (UTD)
IV, pulse ox, monito, EKG (in 10 min) - Oxygen is sat < 90% Aspirin (160-325mg, po/pr) - only thing shown to reduce mortality! - contraindications: bleeding ulcer, anaphylaxis Pain control: morphine or fentanyl Nitrates (NTG) - sublingual q 5 min x 3 - if pain relieved, nitropaste to chest - if no pain relief or labile BP, start drip - contraindicated: hypotensive (BP<90 systolic, HR<50) or RV infarct
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nitroglycerin (NTG) treatment - chest pain or suspicion of MI
sublingual q 5 min x 3 - if pain relieved, nitropaste to chest - if no pain relief or labile BP (fluctuates from normal to high); start drip Contraindicated: hypotensive (BP<90 systolic, HR<50) or RV infarct
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If patient is have an (N)STEMI (based on EKG, troponin levels, etc.) - additional treatment
percutaneous coronary interventions (PCI) - stent - door to "balloon time" is 90/120 min of ED arrival (120 min if not PCI capable facility and transport needed) thrombolysis ("-ases") w/in 30 minutes if not PCI center (can't balloon)
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thrombolytics for acute MI
clotbusters ("-ases") - tPA, Streptokinase (SK) , tenecteplase(TNKase), reteplase (rPA) successful reperfusion rates between 60-80% main complication is bleeding (rare but often fatal b/c intercerebrayl hemorrhage = ICH)
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PCI (Percutaneous Coronary Intervention)
gold standard for acute MI (NSTEMI or STEMI) - preferred to thrombolytics if available - door-to-balloon time is ideally within 90 minutes aka: balloon angioplasty, stenting
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chest pain presents to ER - where patient should go from there
telemetry (admit and watch): concerning hx. w/ no ST elevation, pain free, normal troponin Cardiac ICU: actue MI, ongoing pain, elevated troponin, NTG drip home (low risks patients): - low HEART score (0-3) - two negative troponin, 3 hrs apart - single lab troponin negative 6 hrs from onset of sx w/ constant pain
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once you send for a troponin in ER > opened door to potential cardiac disease - what's appropriate follow-up
must initiate provocative testing within 72 hours (in outpatient setting) - stress tests
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various stress tests
performed in outpatient setting to assess myocardial health Treadmill: least expensive, most available, but lowest sensitivity (68%) Stress echo: no radiation, better sensitivity (80%) Nuclear Stress Testing: (myocardial perfusion imaging) highly accurate, but radiation, takes longer
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chest pain presents to ER (diagnostic tests performed) - risks scores that help to decide next steps
HEART: more appropriate for ED patients (low risk = discharge home = score 0-3) TIMI: simple but poor predictive value for ED (low risk = score of 0-1) - used by PCP and cardiac docs Both: mdcalc.com
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HEART score
risk score used to determine if patient should be sent home, admit for clinical observation, or early invasive strategies performed following presentation to ER with chest pain - 0-3: d/c home for out patient f/u - 4-6: consider admit - 7-10: admit and diagnostics Takes into account: - History - EKG - Age - Cardiac Risk Factors - Troponin Allows for clinical gestalt (judgement)
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GI cocktail
mix of medications that can be given to receive chest pain possibly due to indigestion - caution: can make an MI feel better, so caution if think pt should be admitted (possibly do not want to take away sxs)
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cocaine chest pain - basics and what to avoid
stimulatory: leads to vasoconstriction, inc. platelet aggregation, atherosclerosis - MI occurs in 6% of abusers w/ chest pain Tx: benzodiazepine (combat agitation, HNT, tachycardia) AVOID beta blockers > leads to unopposed alpha agonist effect and worsening vasoconstriction
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cardiogenic shock
insufficient cardiac output to meet metabolic demands of the tissues Hypoperfusion = hypotension, tachy or brady-cardia, cool mottled skin, altered mental status, oliguria (dec. urine output) Emergency!!
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left-sided heart failure - sxs
pulmonary edema, frothy sputum, orthopnea (SOB when flat), dyspnea on exertion systolic dysfunction: EF<40%
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right-sided heart failure - sxs
dependent edema, hepatic enlargement, JVD | usually result of left-sided failure
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heart failure - CXR findings and labs
cephalization: dilated upper lung vessels Kerley B lines: horizontal lines of congestion at bases of lungs overall: pulmonary congestion Labs: BNP (brain natriuretic peptide)
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heart failure - ER treatment
sit up, give O2, nitroglycerin small amounts of fluid, treat dysrhythmias or electrolyte balance send for Eco / ADMIT
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pulmonary embolism - classic triad of sxs
chest pain, dyspnea, hemoptysis (coughing up blood)
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virchows triad
factors thought to contribute to thrombosis ``` hypercoagulable state venous stasis (or turbulence) endothelial injury: from HNT, etc. ```
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pulmonary embolism - CXR findings
hampton's hump: wedge shaped opacification suggesting infarct distal to emboli westermark's sign: dilation of pulmonary vessels proximal to embolism
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hampton's hump
CXR finding: wedge shaped opacification suggesting infarct distal to emboli - pulmonary embolism
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Westermark's sign
CXR finding: dilation of pulmonary vessels proximal to embolism w/ collapse of distal vessels - pulmonary embolism
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Homan's sign
pain w/ squeeze of calf - positive result significant for DVT
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phlegmasi cerculea dolens
cyanotic limb due to swelling - positive result significant for DVT
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Stanford Type A
classification for aortic dissection: involves ascending aorta (even if also involves descending)
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Stanford Type B
classification for aortic dissection: dissection beyond brachiocephalic trunk
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cardiac tamponade
blood or fluid in pericardium prevents heart ventricles from expanding fully; excess pressure province heart from working properly - Beck's triad: distant heart sounds, hypotension, JVD - pulsus paradoxus: on exam, detect beats on cardiac auscultation during inspiration that cannot be palpated on radial pulse - electrical alterans: on EKG - alternating QRS axis
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Beck's triad
distant heart sounds, hypotension, JVD significant for cardiac tamponade
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pulsus paradoxus
on exam, detect beats on cardiac auscultation during inspiration that cannot be palpated on radial pulse significant for cardiac tamponade
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electrical alterans
on EKG - alternating QRS axis significant for cardiac tamponade
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Dresslers Syndrome
pericarditis following MI, surgery or trauma immune system response after damage to heart muscle (occurs within 1st week after surgery)
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Boorhave's Syndrome
esophageal rupture - air where it should not be (Hamman's crunch) - retching (dry-heaving), vomiting (blood) - ETOH abuse or ulcer
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Hamman's crunch
crackles that correlate with heart beat (heard on auscultation); heart beating against air-filled tissues (air where it should not be) happens with: - esophageal rupture - pneumomediastinum - pneumopericardium
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acetaminophen
tylenol, non-narcotic, mild or moderate pain peds 15mg/kg (max adult 4g/day) analgesia only (no anti-inflammatory or anti platelet) can use in children <6mo
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NSAIDS - Ibuprofen (mortrin, advil) and naproxen (aleve)
non-narcotic, mild or moderate pain, anti-inflammatory, anti-pyretic peds 10mg/kg (max adult 2400mg/day) inhibit COX-1 and COX-2 (prostaglandin) synthesis avoid: kids <6mo, 3rd trimester preg
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Ketorolac / Toradol
non-narcotic, IV version of highly effective NSAID | good for renal colic (abd pain caused by kidney stones), migraines
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aspirin
use: dec risk of non-fatal MIs, cancer avoid in children and adolescents (Reyes - brain and liver swelling) and 3rd trimester preg
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hydrocodone
oral, narcotic, mild to moderate pain used in conbo w/ tylenol (Norco, vicodin) or Ibuprofen (vicoprofen) less potents than oxycodone fewer side effects than codeine
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codeine
oral, narcotic usually combined w/ aspirin or tylenol metabolism issues: rapid and poor great anti-tussive
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tramadol
oral, narcotic good for chronic pain (fibromyalgia)
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morphine sulfate
narcotic by which all others compared, IV 3rd fastest of morphine, hydromorphone, and fentanyl - onset: 5-10min; duration 2-6 hrs hypotension and pruritis
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hydromorphone (Dilaudid)
opioid (narcotic), stronger than morphine sulfate w/ less pruritis, nausea, hypotension 2nd fastest of morphine, hydromorphone, and fentanyl - onset 3-5 min IV; duration 2-4 hrs note: great bioavailability when given orally
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fentanyl
opioid (synthetic narcotic), 100x more potent than morphine Fastest of morphine, hydromorphone, and fentanyl (fentanyl = FAST) - onset 1 min, duration 30-min Often combined with Versed for "conscious sedation" comes in many forms: lolli-pop, transdermal patch, IN Caution: glottic wall rigidity Reversal agent: Naloxone
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conscious sedation
fentanyl with versed
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narcotic reversal agents
methadone: used for managing opioid addiction (fatal arrhythmias, QT prolongation) Suboxone: contains buprenorphine and naloxone; used for managing opioid addiction (ST and LT replacement therapy Naloxone: opioid antagonist that "kills high" + rapid withdrawal sxs if misuse
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Clonidine
can be used for acute opiate withdraw (mainly do sxs managment)
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Versed
benzodiazepine respiratory and CV depression onset 1 min, lasts 1 hour