Exam 1 Flashcards

(28 cards)

1
Q

An enzyme used in both glycolysis and gluconeogenesis is:

A

Phosphohexoisomerase

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2
Q

ATP can be hydrolyzed by several ways. In presence of COOH, which pairs of reactions the ATP provide MOST energy:

A

R-COOH + ATP + R-po2-Adenine+ PPi

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3
Q

How does Arsenate affect glycolysis:

A

It lead to the net production of no ATP

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4
Q

The main function of pentose phosphate pathway is to:

A

Supply pentose and NADPH

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5
Q

Which of the following are effects of Epinephrine: (K-type Q)

A

1) Activates glycogen phosphorylase

2) Blocks activation of glycogen synthase

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6
Q

Indicate the appropriate intermediate in the catabolism of lactose by completing the following sentences; Lactose is first broken into its component monomers one of these is glucose, the other is ___, can be catabolised through multi steps process to form ___ and intermediate of glycolysis.

A

Galactose, glucose-6-phosphate

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7
Q

The last step of glycolysis involve the conversion of phosphophenol pyruvate to pyruvate synthesized glucose, most organism accomplish the reversal of this reaction by employing a series of reactions different from the glycolytic reaction which bypass the glycolytic reaction.
2 Q’s are about this series of reaction:
1) Which of the following is true about this bypass:
2) Assuming that Lactate is not available how is NADH involve in the reversal reaction;

A

1) The reaction have a net requirement of 2 ATP equivalent per pyruvate
2) 1 mole is consumed in mitochondria and formed in the cytosol for each mole of pyruvate consumed

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8
Q

How many ATP equivalent and molecule of NADH are directly required for the synthesis of one molecule of glucose:

A

6 ATP, 2 NADH

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9
Q

Which of the following pairs of reaction is futile cycle:

A

Pyruvate + ATP + Posphophenolpyruvate + ADP Posphophenolpyruvate + H2O –> pyruvate + Pi

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10
Q

Which of the following is true about this pair of reactions : fructose 6 phosphate+ATP—fructose 1,6 phosphate +ADP

A

AMP promote reaction # 1 and inhibit reaction #2

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11
Q

Which of the following is true about the regulation of hexokinase:

A

Both 2 and 3:

2) in muscle tissue it is regulated by feed back inhibition
3) in liver tissue it is regulated primarily by the glucose concentration

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12
Q

There is resceprocal regulation of glycolytic and glucogenic reaction interconverting fructose 6 phosphate and fructose 1,6 biphosphate. What about this regulation is not correct:

A

Phosphofructokinase is endergonic

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13
Q

Pyruvate can either undergo a series of catabolic reactions yield energy or to be transformed into glucose (gluconeogenisis). The primary way of regulation how pyruvate is metabolized:

A

Acetyl Co promotes gluconeogensis and inhibits the catabolism of pyruvate

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14
Q

Which of the following will low blood glucose promote:

A

Activation of FBPase and inactivation of Pfk-1

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15
Q

The primary immediate product of glycogen break down is ——glucose 1-phosphate, the immediate substrate of glycogen is:

A

UDP glucose

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16
Q

Which of the following statements is true about the regulation of pyruvate kinase?

A

Both: An elevated ATP inhibit PK AND elevated Glucagon lead to inactivation to PK

17
Q

Glycogenin is:

A

The primer on which new glycogen chains are initiated

18
Q

The enzyme PP1 catalyses the inactivation of glycogen phosphorylase and activation of glycogen synthase, which are inhibitors to PP1:

A

Epinephrin and glucagon

19
Q

Which of the following decrease glycogen phosphorylase activity activity?

20
Q

Which of the following sweeteners doesn’t provide energy? The question was long and talking about a gum and listed a lot of sweeteners can’t remember the whole question..

21
Q

Which of the following sweeteners is not FDA approved?

22
Q

Which of the following is a concern when patient has phenyketouria?

23
Q

On the box of wheat cheerios the amount of fiber is 5 g what is the % of DV?

24
Q

Which of the following is not true regarding insoluble fibers?

A

It lowers the cholesterol blood level

25
Which of the following is true regarding soluble fibers?
They are digested by bacteria in the intestine
26
Which of the following is not true regarding GSK3?
It’s stimulated by epinephrine and causes phosphorylation and thus activation of glycogen synthase
27
Which of the following is true regarding glycogen synthase?
It’s inhibited by epinephrine and causes de-phosphorylation of the enzyme
28
What are the dietary recommendations of CHO OF 2000Kcal?
45 - 65%