Exam 1: CNS Flashcards

(90 cards)

1
Q

PGC’s are visible in the yolk sac during which weeks of gestation?

A

4-6

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2
Q

When do PGC’s become gonocytes?

A

When they reach the gonads

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3
Q

When PCG’s reach the gonads and become gonocytes, which supporting cells are secreted?

A

Sertoli cells (male) granulosa cells (female)

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4
Q

What is the era of spermatogenesis?

A

Puberty to death

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5
Q

What regulates spermatogenesis?

A

Testosterone and androgen receptors

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6
Q

Does spermatogenesis create spermatozoa through mitosis or meiosis?

A

Meiosis

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7
Q

How long does spermatogenesis take?

A

2 months

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8
Q

The 2nd meiotic division occurs…

A

hours before ovulation occurs

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9
Q

Does a teratogen affect all the body systems at the same time?

A

No, not all body systems develop at the same time so a teratogen can affect 1 without affecting the others

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10
Q

What happens during week 1?

A

Fertilization and zygote formation

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11
Q

What happens during week 2?

A

Implantation, bilaminar disc forms, placenta forms, amniotic fluid forms

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12
Q

What happens during week 3?

A

Gastrulation, neural crest formations, and embryonic folding

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13
Q

Where does implantation usually occur?

A

Posterior uterus wall

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14
Q

Important for blood cell, germ cell, and gut development?

A

Yolk sac

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15
Q

Transfers nutrients during the early stages of development?

A

Yolk sac

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16
Q

How are chorionic villi formed?

A

By extension of the cytotrophoblast and then grow into the syncytiotrophoblast

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17
Q

Polyhydramnios

A

Too much amniotic fluid

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18
Q

Oligohydramnios

A

Too little amniotic fluid

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19
Q

What is special about the buccopharyngeal (oropharyngeal) and cloacal membranes?

A

They do not trilaminate. They remain bilaminar

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20
Q

The primitive streak is formed by the proliferation & movement of which cells to the median plane?

A

Epiblast

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21
Q

Cells that travel through the primitive streak first & displace the hypoblast?

A

Endoderm

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22
Q

Which structure induces the overlying ectoderm to form the central nervous system

A

Notochord

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23
Q

When does the primitive streak disappear?

A

At the end of week 4

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24
Q

Neural crest cells arise directly from:

A

Dorsal part of the neural tube

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25
Ectomesenchyme develops directly from:
Neural crest cells
26
A sacrococcygeal teratoma forms by:
Remnants of the primitive streak
27
Which type of folding forms the stomodeum?
Longitudinal
28
The stomodeum is a:
Ectoderm pouch located between the future brain & developing heart
29
What is the embryonic stage at which implantation occurs?
Blastocyst day 7
30
Which structure induces the neural tube to form?
The notochord
31
What event must occur in order to form the gut tube?
Gastrulation
32
Which structure is formed by epiblast cells which migrate through the primitive streak?
The notochord
33
Which structure forms all three germ layers during gastrulation?
Epiblast
33
The neural tube is commonly referred to as:
The CNS
34
Where does the ectomesenchyme come from?
Neural crest cells which arise from the ectoderm
35
Describe the structure of motor neurons (multipolar)
2 or more dendrites and a single axon
36
Describe the structure of sensory neurons (pseudounipolar)
Short apparently single, but actually double, process
37
Central Process
Cell body to CNS
38
Distal Process
Receptor organ to cell body
39
Where does the spinal cord run?
Medulla to L1 vertebrae
40
The dorsal root (spinal) ganglion is a collection of cell bodies located:
Outside CNS
41
What is gray matter made up of?
Cell bodies of neurons
42
What is white matter made up of?
Axons of neurons
43
Axonal pathways within white matter:
Funiculus, tract, lemniscus, bundle, fasciculus
44
Where does CSF drain to?
Subarachnoid space then to venous system
45
Location of upper motor neurons?
cerebral cortex
46
Location of lower motor neurons?
brainstem or spinal cord
47
Explain the difference between 1st/2nd/3rd order neurons and upper/lower neurons?
1st/2nd/3rd order refers to sensory afferent neurons while upper/lower refers to motor efferent neurons
48
How many enlargements does the spinal cord have and where are they located?
2; cervical and lumbar
49
Explain why cell bodies are divided up into nuclei and ganglion?
Nuclei refer to cell bodies within the CNS; ganglion refer to cell bodies outside the CNS
50
Explain why axons are divided up into tracts and nerves?
Tract refers to axons within the CNS; nerve refers to axons outside the CNS
51
Dorsal (Posterior Horn)
Pain, temp, proprioception
52
Lateral Horn
Autonomic NS (parasympathetic and sympathetic)
53
Ventral (Anterior) Horn
Motor function to trunk and limbs (lower motor neurons)
54
Dorsal (Posterior) Funiculi
Discriminative touch, proprioception, and vibration; fasciculus gracilis (legs) and fasciculus cutaneus (arms)
55
Lateral Funiculi
Pain, + temp (lateral spinothalamic), motor to limbs (lateral corticospinal), balance (spinocerebellar)
56
Ventral (Anterior) Funiculi
Crude touch + pressure (anterior spinothalamic), somatic motor to trunk (anterior corticospinal)
57
List the function of the medulla
Respiration, cardio-inhibitory, vasomotor, vomiting, coughing, sneezing, swallowing
58
List the nuclei of the medulla
Nucleus gracilis, nucleus cuneatus, dorsal vagal motor, pyramids, reticular formation
59
List the tracts of the medulla
medial lemniscus, lateral spinothalamic, pyramidal
60
List the function of the pons
Micturition, sleep + arousal, respiration
61
List the nuclei of the pons
Reticular formations
62
List the tracts of the pons
Medial lemniscus, lateral spinothalamic, pyramids
63
List the function of the midbrain
Vision, hearing, motor control, sleep + arousal, alertness, temp regulation
64
List the nuclei of the midbrain
Reticular formation
65
List the tracts of the midbrain
Medial lemniscus, lateral spinothalamic, pyramids
66
Describe the function of the pyramidal tract
Axons convey motor innervation to skeletal muscles
67
Describe the function of the medial lemniscus tract
Axons conveying discriminative touch
68
Describe the function of the lateral spinothalamic tract
Axons conveying pain + temp from the body
69
Describe the function of the cerebellum
Coordination of movement, sets rate + force *indirect motor pathway
70
Describe the function of the basal ganglia
Grey matter deep + superficial with white matter in the middle, permits/suppresses movement
71
Broca's area
Non-fluent aphasia, difficulty speaking + finding words; limited to L hemisphere
72
Frontal Lobe
Problems solving, planning, voluntary movement, personality, concentration
73
Precentral Gyrus
In frontal lobe, primary MOTOR cortex, projects contralateral
74
Superolateral
Upper limb
75
Inferolateral
Head
76
Medial
Lower Limb
77
Parietal Lobe
pain, temp, touch, emotional language, understanding speech
78
Postcentral gyrus
In the parietal lobe, primary somatosensory cortex, projects contralateral
79
Wernicke's Area
Comprehension affected, can speak but words don't make sense
80
Temporal Lobe
Auditory processing, memory, language, emotional processing
81
Occipital Lobe
Vision
82
Insular Lobe
Within lateral cerebral sulcus, taste, smell, balance, pain
83
Ventral Lateral/Ventral Anterior
motor
84
Ventral Posterior Lateral (VPL)
pain, temp, touch from BODY
85
Ventral Posterior Medial (VPM)
pain, temp, touch from HEAD
86
Medial Geniculate Nucleus
Auditory
87
Lateral Geniculate Nucleus
Vision
88
Hypothalamus
Homeostasis, hormones
89
Limbic System
Regulates behaviors & instincts essential for survival