Exam 1 drugs

Question 1

What type of drug is amitriptyline?

Answer 1

Tricyclic antidepressant (TCA)

Question 2

What type of drug is imipramine?

Answer 2

Tricyclic antidepressant (TCA)

Question 3

What type of drug is escitalopram (Lexapro) ?

Answer 3

SSRI

Question 4

What type of drug is fluoxetine (Prozac)?

Answer 4

SSRI

Question 5

What type of drug is sertraline (Zoloft)?

Answer 5

SSRI

Question 6

What type of drug is venlafaxine (Effexor ER)?

Answer 6

SNRI

Question 7

What type of drug is duloxetine (Cymbalta)?

Answer 7

SNRI

Question 8

What type of drug is phenelzine (Nardil)?

Answer 8

MAOI (monoamine oxidase inhibitor)

Question 9

What type of drug is tranylcypromine (Parnate)?

Answer 9

MAOI

Question 10

What type of drug is isocarboxazid (Marplan)?

Answer 10

MAOI

Question 11

What type of drug is bupropion (Wellbutrin)?

Answer 11

Atypical antidepressant

Question 12

List 2 examples of tricyclic antidepressants

Answer 12

Amitriptyline

Imipramine

Question 13

What are tricyclic antidepressants commonly used for?

Answer 13

depression
anxiety
insomnia
fibromyalgia 
bipolar disorder
OCD
ADHD

Question 14

What do tricyclic antidepressants do?

Answer 14

Block uptake of norepinephrine and serotonin

Increase concentration of serotonin and norepi in body, block acetylcholine, hence the anticholingeric effects

Question 15

Nursing interventions of Tricyclic antidepressants (TCAs)

Answer 15

Take at bedtime
Take with food if GI upset
Change positions slowly
Chew sugarless gum if anticholinergic effects (dry mouth)
Increase fluid intake to 2-3L/day
High fiber foods (Avoid constipation)

Question 16

List 3 examples of SSRIs

Answer 16

1. escitalopram (Lexapro)
2. fluoxetine (Prozac)
3. sertraline (Zoloft)

Question 17

What do SSRIs do?

Answer 17

First line treatment for panic disorders and trauma

SSRIS block the reuptake of serotonin!! Increase concentration of serotonin in body!

Question 18

Common side effects of SSRIs:

Answer 18

Weight gain
Nausea/GI upset
BBW suicide
Sexual dysfunction
Insomnia
Serotonin syndrome
Hyponatremia (increased ASH, fluid retention, Na+ diluted)

Question 19

Nursing interventions SSRIs

Answer 19

Take in morning with food for GI upset
Report impotence/decreased libido
S/S hyponatremia
Do not stop taking abrupty. Education on slow onset (2-4 weeks)
Never mix St. John’s Wort, MAOIs with SSRIs

Question 20

Adverse drug reactions for TCAs:

Answer 20

Anticholinergic effects (too much= CNS depression)
HIGH** risk of drug overdose due to narrow therapeutic index:  can cause dysrythmias, confusion, seizures. 
BBW suicide

Question 21

Name 2 SNRIs

Answer 21

Venlafaxine (Effexor XR)
Duloxetine (Cymbalta)

Remember: vexed and Depressed

Question 22

What are SSRIs mainly prescribed for?

Answer 22

Depression, Panic, OCD

Question 23

What do SNRIs do?

Answer 23

Block uptake of norepi and serotonin

Question 24

What happens if you have high levels of Norepinephrine

Answer 24

Tachycardia
Fight or Flight
Urinary retention
Increased Blood glucose
decreased GI motility (constipation)
Anorexia (not focused on eating)
Increased BP

Question 25

What are SNRIs typically prescribed for?

Answer 25

Major depression, panic disorders, panic disorders, generalized anxiety disorders

Question 26

What are adverse drug reactions of SNRIs?

Answer 26

``` CNS excitement: insomnia and nervousness Nausea, GI upset, Heptatitis Hyponatremia (ADH affected by serotonin) Hypertension Anorexia BBW suicide! ```

Question 27

Client education for SNRIs

Answer 27

``` Take with food Avoid taking close to bedtime Monitor BP Never stop abrupty! Dont take other supplements without consulting Doc. ```

Question 28

List 2 examples of MAOIs

Answer 28

phenelzine (Nardil) | Tranylcypromine (Parnate)

Question 29

What do MAOIs do?

Answer 29

Increases amounts of serotonin, norepinephrine, and dopamine

Question 30

Adverse drug reactions of MAOIs

Answer 30

``` CNS excitement: agitation, insomnia, mania Orthostatic hypotension GI upset N/V Liver/Kidney issues ```

Question 31

What conditions are MAOIs typically prescribed for?

Answer 31

``` Depression Bulimia Panic disorder Social anxiety disorder PTSD ```

Question 32

What should not be taken with MAOIs?

Answer 32

Foods containing tyramine TCAs Sympathomimetics Sudafed, Coke, Adderall Can cause hypertensive crisis!!!!!