Exam 1 Example 2

Question 1

The world population reached 4 billion in 1974. This number will double when?

Answer 1

Answer on practice: 2024, but check notes for more accurate timeline

Question 2

The first mammalian clone “Dolly the Sheep” was made in 1996 by?

Answer 2

Ian Wilmut

Question 3

In 1982, the first FDA approved biotech drug “Humulin” was developed by

Answer 3

Bayer

Question 4

Bioremediation is the process to

A. Synthesize organic product
B. extract and purify protein of interest
C. degrade pollutant
D. reuse metabolic compounds
E. generate green energy

Answer 4

c. degrade pollutant

Question 5

PDMS is a common biomaterial in which the stiffness and density can be controlled via adjustment of

A. temperature
B. humidity
C. curing time
D. ratio of curing agent
E. all of the above

Answer 5

d. ratio of curing agent

Question 6

The light sensitive material utilized in the photolithography process is

A. wafer
B. photoresist
C. mask
D. master
E.PDMS

Answer 6

b. photoresist

Question 7

Artificial hip joints often consist of the following materials EXCEPT

A. polymer
B. alloy
C. ceramics
D. minerals
E. thermoplastics

Answer 7

d. minerals

Question 8

Fundamental principles of continuum mechanics obeys the following laws EXCEPT

A. conservation of energy
B. conservation of mass
C. conservation of linear momentum
D. conservation of shear momentum
E. conservation of angular momentum

Answer 8

d. conservation of shear momentum

Question 9

An ideal biomaterial for dental root implants is

A. ceramics
B. polymer
C. stainless steel
D. magnesium alloy
E. titanium alloy

Answer 9

e. titanium alloy

Question 10

Which one of the following is an example of scalar quantity

A. force
B. speed
C. velocity
D. acceleration
E. momentum

Answer 10

b. speed

Question 11

In biomechanical perspective, strain is a measure of

A. durability
B. force distribution
C. deformation
D. flexibility
E. density

Answer 11

c. deformation

Question 12

ECMO

A. is a kidney dialysis machine
B. is a respiratory support device
C. is an external hepatic assist machine
D. supports oxygenation to the heart and lung
E. supports enzymatic detoxification function

Answer 12

d. supports oxygenation to heart and lungs

Question 13

Force law that describes inertia is?

Answer 13

Newton’s first law

Question 14

Blood Aspartate aminotransferase (AST) level is a biomarker for

A. kidney function
B. cardiac function
C. liver function
D. vascular disease
E. immune response

Answer 14

c. liver function

Question 15

A spectrophotometer analyze the biological specimen by characterizing the

A. molecular charge
B. molecular mass
C. molecular structure
D. molecular density
E. chemical volatility

Answer 15

b. molecular mass

Question 16

The order of steps in a standard PCR cycle is

Answer 16

denaturing –> annealing –> extension

Question 17

Digital PCR is considered to be a more advanced platform than qPCR because

A. capability to perform absolute quantification
B. capable of ultra-sensitive detection
C. does not require amplification steps
D. fast processing time
E. lower operation cost

Answer 17

a. capability to perform absolute quantification

Question 18

Which of the following description about Sanger sequencing is INCORRECT

A. incorporation of dNTPs terminator during the extension process
B. invented by Frederick Sanger
C. also known as “sequencing by synthesis”
D. can only read a few hundred base-pairs of any continuous fragment
E. is the method utilized to sequence the first draft of human genome

Answer 18

c. also known as “sequencing by synthesis”

Question 19

Next Generation Sequencing (NGS) platforms includes the following examples EXCEPT

A. Ion Torrent platform
B. ABI SOLiD platform
C. Illumina platform
D. Pyrosequencing
E. Shotgun sequencing platform

Answer 19

E. Shotgun sequencing platform

Question 20

Which one of the following is NOT an example of molecular diagnostic platform

A. Mass Spectrometry
B. PCR
C. Sequencing
D. Microarray
E. MRI

Answer 20

e. MRI

Question 21

X-ray emission is discovered by

Answer 21

Roentgen

Question 22

Computer Tomography (CT) is based on which of the following technology platform?

Answer 22

X-rays

Question 23

All of the following are examples of non-invasive diagnostic techniques EXCEPT

A. MRI
B. Pulse Oximetry
C. Blood pressure monitor
D. Blood glucose monitor
E. Infrared thermometer

Answer 23

d. blood glucose monitor

Question 24

Cobalt 60 is the energy source of

A. Gamma knife
B. Cyber knife
C. Proton therapy
D. Heavy ion/ HIMAC system
E. X-ray therapy

Answer 24

A. Gamma knife

Question 25

Which of the following DNA vector is capable of harboring the largest insert size? A. cosmid vector B. yeast vector C. plasmid vector D. bacterial phage vector E. bacterial artificial chromosome (BAC) vector

Answer 25

b. yeast vector

Question 26

In pulse oximetry device, oxygenated hemoglobin has a higher absorbance of which wavelength? A. 640 nm B. 660 nm C. 920 nm D. 940 nm E. 960 nm

Answer 26

d. 940 nm

Question 27

In sub-atomic physics field, Higgs Boson is often referred as A. angel particle B. saints particle C. god particle D. dark matter E. anti matter

Answer 27

c. god particle

Question 28

Juan injured his leg and was taken to the ER with a suspected broken bone. What would be the ideal imaging diagnosis mode for him, and what is one advantage and one disadvantage (i.e. potential side effect) of this diagnostic technology?

Answer 28

Example answer, but explore more in notes: "An x-ray can be used ideally. Get a clear 2D image of the bone to see if fractured. However, it does not compare to CT scans since x-rays are only 2D. Also, radiation is one side effect since it can cause mutations in DNA if conducted too much.

Question 29

Describe 3 major functions of the heart

Answer 29

1. Generating Blood Pressure: Required for blood flow through the blood vessels 2. Routing Blood: Two pumps, moving blood through the pulmonary and systemic circulations 3. Regulating Blood Supply: Adjusts blood flow by changing the rate and force of heart contractions as needed

Question 30

Recognize the Navier-Stokes equation and all of its parts!

Answer 30

Inertia force = (-)Pressure gradient + Body Force + Viscosity

Question 31

Heart valve replacement is a common procedure in cardiology field. Explain the difference between a xenograft valve and mechanical valve. List one advantage and one disadvantage associated with EACH type of valve

Answer 31

Example answer, but review from slides - Xenograft: Animal one is good because if taking immune suppressing drugs your immune system won't attack it, but disadvantage is it only lasts for like 10 years. - Mechanical: Artificial one made by biomaterials which allow it to last longer than xenograft. However, a disadvantage is that it can crush RBCs which in turn cause coagulation.

Question 32

Explain the functions/ roles of Caspase 9 enzyme and gRNA of CRISPR genome editing technology

Answer 32

Look at notes.