Exam 1 - Holmes' drugs/toxins Flashcards
1
Q
Digoxin
A
inhibit Na/K pump, increase contractility of heart
2
Q
Oubain
A
inhibit Na/K pump, increase contractility of heart
3
Q
Palytoxin
A
binds and locks open Na/K pump
4
Q
Halothane
A
gaseous anesthetic activates K channels
5
Q
Isoflurane
A
gaseous anesthetic activates K channels
6
Q
EtOH
A
inc conductance of GABA channels, anesthetic
7
Q
Lidocaine/Procaine
A
local anesthetics, block Na channels
8
Q
Phenytoin
A
anticonvulsant, inhibits Na channels
9
Q
Carbamazepime
A
anticonvulsant, inhibits Na channels
10
Q
Dofetilide
A
antiarrhythmic, blocks delayed rectifier Kv channels
11
Q
Tertrodotoxin
A
blocks Na channel
12
Q
Saxitoxin
A
blocks Na channel
13
Q
Propofol
A
blocks Nav channels
14
Q
Neostigmine
A
blocks AChE, tx for MG
15
Q
hemicholinium
A
blocks choline re-uptake
