Exam 1 Material Flashcards
(462 cards)
What are the four basic tissues of the human?
epithelial, muscle, neural & connective tissue
What is the function of each type of bone cell?
osteoblast - form bone
osteocyte - maintain or nurture bone
osteoclast - remodel bone
What are the bone cells embedded in?
an amorphous matrix consisting of ground substance, protein fibers and various minerals
What is the primary constituent of the ground substance?
glycosaminoglycans
What types of glycosaminoglycans predominate in bone?
chondroitin sulfates, keratin sulfates & hyaluronic acid
What is the principle type of protein fiber in bone?
collagen type I
What are the primary constituents of the bone mineral?
calcium, phosphate, citrate & carbonate ions
What is the most frequently described deposit in bone?
hydroxyapatite
Bone is also the repository for what additional ions?
sodium, magnesium, fluoride, lead, strontium & radium
What is Wolff’s Law as it pertains to bone?
living tissue will respond to stressors such as anxiety, tension or pressure; bone is formed or absorbed in response to these same stressors
What three responses of “living” bone were stressed in class?
it has the ability to heal, to remodel under stressor such as anxiety, tension nor pressure and to age
Bone is the embryological derivative of which specific connective tissues?
mesenchyme and/or cartilage
What is the name given to the pattern of ossification in mesenchyme?
intramembranous ossification
What is the timing for the appearance of intramembranous ossification?
from the second to third month in utero
What part of the axial skeleton is primarily formed by intramembranous ossification?
the skull
What is the name given to the pattern of ossification in cartilage?
endochondral ossification
Wha tis the timing for the appearance of ossification in cartilage?
from the second to fifth month in utero
Which skull bones are ossified by both endochondral and intramembranous ossification?
the mandible, sphenoid, temporal & occipital bones
Which bone of the appendicular skeleton is formed by both endochondral and intramembranous ossification?
the clavicle
Wha tare the names given to the venters of ossification based on time of appearance?
primary centers of ossification appear before birth
secondary centers of ossification appear after birth
Mature bone is described as being composed of what areas based on bone density?
cortical or compact bone and spongy, cancellous or trabecular bone
What is the name given to the bone below an articulating surface?
subchondral bone
What is the name of the outer fibro-cellular covering of a bone?
the periosteum
What is the name given to the fibro-cellular lining of bone?
the endosteum