Exam 1 - Practice Quiz

Question 1

Swine influenza

Answer 1

Shope

Question 2

Rabies vaccine, beer, father of microbiology

Answer 2

Louis Pasteur

Question 3

Genome project

Answer 3

Craig Venter

Question 4

1st virus discovered, Foot and mouth disease, postulates

Answer 4

Loffler, Frosch, Koch

Question 5

Concept of possible vaccination, small pox in people

Answer 5

Edward Jenner

Question 6

Globally eradicated

Answer 6

Small pox (1980), Rinderpest (2011)

Question 7

Human measles/canine distemper

Answer 7

Viral family relationship

Question 8

Respiratory vs. enteric vs. congenital

Answer 8

Epidemiological grouping of viruses

Question 9

Cell receptor complementarity

Answer 9

Characteristics of host cell

Question 10

Capsid, intracellular replication, DNA or RNA

Answer 10

Basic characteristics/structures of viruses

Question 11

Feline panleukopenia/canine parvovirus

Answer 11

Viral family relationship

Question 12

Cytopathic (cell death, giant cells/syncytia, inclusions), oncogenic formation

Answer 12

Cellular changes due to viral infection

Question 13

Laboratory measurements of viral infectivity

Answer 13

TCID50 and plaque assay

Question 14

Pathogenicity

Answer 14

Ability of virus to cause disease

Question 15

Immune defenses, susceptibility, age, genetics

Answer 15

Host influence on infection outcome

Question 16

Papilloma wart in skin

Answer 16

Localized infection

Question 17

Numbers of particles, virulence, ability to damage cells, tropism

Answer 17

Virus influence on infection outcome

Question 18

Respiratory, neurological, gastrointestinal signs in CDV

Answer 18

Systemic infection

Question 19

Latent-recurrent infection

Answer 19

Herpesviruses

Question 20

Acute self-limiting infection

Answer 20

Influenza viruses

Question 21

Acute infection with late complication

Answer 21

Canine distemper virus

Question 22

Slow infection ending in disease episode

Answer 22

Prion diseases

Question 23

Chronic infections

Answer 23

FIP

Question 24

Chronic infection with late disease

Answer 24

FeLV, FIV

Question 25

Staining of tissue sections

Answer 25

Detect virus - immunohistochemistry, immunofluorescence, in-situ hybridization

Question 26

Snap tests

Answer 26

Either detect virus or detect antibodies - ELISA

Question 27

Antibody titer

Answer 27

Detect antibodies - ELISA, virus neutralization, hemagglutination inhibition

Question 28

Cell culture of nasal swabs

Answer 28

Detect virus - virus isolation

Question 29

Visualize viral particles

Answer 29

Detect virus - electron microscopy

Question 30

Identification of RNA or DNA

Answer 30

Detect viral genome (antigen) - PCR, gene sequencing

Question 31

Egg inoculation

Answer 31

Detect virus - virus isolation (used for Influenza)

Question 32

For diagnostic purposes, important to try to collect samples when peak viremia occurs. This optimized chances of detecting virus in collected specimens. When does peak viremia occur?

Answer 32

When fever peaks (pyrexia)

Question 33

Still has abilty to infect cells, may still be virulent in some species

Answer 33

Modified live (attenuated)

Question 34

Use ELISA to detect antibodies to wild type but not marker vaccine strain

Answer 34

DIVA - differentiation of infected from vaccinated animals

Question 35

Instructs cell to make a specific antigenic protein

Answer 35

mRNA vaccine

Question 36

Use recombinant virus vector from unrelated species

Answer 36

Canarypox for ferret canine distemper (CDV) vaccine

Question 37

Bedding, grooming equipement

Answer 37

Indirect transmission

Question 38

Point mutation that allows infection of a new host species

Answer 38

Antigenic drift

Question 39

Point mutation that allows immune escape

Answer 39

Antigenic drift

Question 40

Prolonged period of viral shedding

Answer 40

Persistent infection

Question 41

Genetic reassortment between viruses results in major antigenic change

Answer 41

Antigenic shift

Question 42

Dead-end host

Answer 42

Infected, but level of viremia not sufficient for transmission to occur

Question 43

Being born

Answer 43

Congenital transmission

Question 44

Rubbing, licking, intercourse

Answer 44

Direct contact transmission