Exam 1 Quiz Qs 1-3 Flashcards

(30 cards)

1
Q

In a voltage clamp, which of the following is measured?

A

Magnitude and direction of the ionic current

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2
Q

How does a voltage clamp work?

A

It holds the voltage of a neuron constant by injecting current equal to the ionic current passing across the cell membrane.

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3
Q

What is the main contributor to the absolute refractory period following the onset of an action potential?

A

Inactivation of voltage-gated sodium channels

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4
Q

Which cells form myelin sheets in the central nervous system?

A

Oligodendrocytes

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5
Q

What is the name of the periodic interruptions of myelin sheets along nerve fibers?

A

Nodes of Ranvier

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6
Q

Which factors make propagation of electrical signals in dendrites more complex than in axons?

A

Dendrites contain a wide variety of different voltage-gated ion channels

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7
Q

What drives primary active transport?

A

The hydrolysis of ATP

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8
Q

What drives secondary active transport?

A

Ion flux down their electrochemical gradient

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9
Q

Why is the sodium–potassium exchange pump said to be electrogenic?

A

Because it transports unequal numbers of sodium and potassium ions across the membrane

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10
Q

How can ion exchange mechanisms be made to run backwards?

A

By altering one or more of the ion gradient involved in the exchange

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11
Q

The neuronal connections in the nervous system can be

A

convergent, divergent, recurrent, or parallel

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12
Q

Which scientist defined the neuron as the single cell unit of the nervous system?

A

Ramon y Cajal

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13
Q

The signal intensity is encoded by which property of the action potential?

A

Frequency

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14
Q

Local graded potentials encode the intensity of a signal by

A

size of the membrane potential change

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15
Q

are arranged with their polar, hydrophilic heads facing outward and their hydrophobic tails extending to the middle of the layer.

A

Plasma membrane lipid molecules

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16
Q

Channel “activation” is a(n)

A

increase in the frequency of channel opening

17
Q

Hyperpolarization occurs when the membrane potential

A

becomes more negative

18
Q

Which is true of the potassium equilibrium potential?

A

It is the membrane potential where electrical forces and concentration gradients are equal and opposite

19
Q

In a model cell at rest, what is the relative concentration of potassium inside the cell?

A

Higher than the concentration of potassium outside the cell

20
Q

The action of the sodium-potassium exchange pump is electrogenic. What does this mean?

A

The exchange pump produces an electrical charge.

21
Q

The signal intensity is encoded by which property of the action potential?

22
Q

Local graded potentials encode the intensity of a signal by

A

size of the membrane potential change

23
Q

Channel “activation” is a(n)

A

increase in the frequency of channel opening

24
Q

In a voltage clamp, which of the following is measured?

A

Magnitude and direction of the ionic current

25
How does a voltage clamp work?
It holds the voltage of a neuron constant by injecting current equal to the ionic current passing across the cell membrane.
26
The late current observed in voltage clamp experiments contributes to which of these phases of the action potential?
Repolarization
27
Which of the following ions is responsible for the late current following a voltage step in a voltage clamp experiment?
Potassium
28
Which of the following can be attributed to the flow of sodium ions across the membrane?
Early current
29
When Hodgkin and Huxley recorded from a neuron under voltage clamp at +52 mV, which of the following describes what they observed?
No early current and an outward late current
29
When triethanolamine (TEA) is applied to a neuron in a voltage clamp experiment, what results are observed?
An inward early current followed by no late current