Exam 1 - Week 1 - Antihistamines Flashcards Preview

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Flashcards in Exam 1 - Week 1 - Antihistamines Deck (5)
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1
Q

MOA of antihistamines

A

Theorized to block the release of histamine from mast cells and basophils in the nasal passageways that are activated by cold virus inoculation. Antihistamines competitively antagonize histamine at the HI receptor, 1st generation antihistamines also competitively antagonize acetylcholine activity at the muscarinic receptor

2
Q

Examples of 1st gen antihistamines

A

Benadryl

3
Q

Examples of 2nd gen antihistamines

A

Claritin and Zyrtec

4
Q

Are 2nd gen antihistamines useful for cough and cold?

A

No.

5
Q

Anithistamine contraindications

A

Lactation, neonates, infants