Exam Flashcards

(17 cards)

1
Q

What are two required parameters of biomaterials used in the clinic?

A

Tissue compatibility (biocompatibility) and mechanical performance appropriate to their function

These parameters are essential for ensuring that biomaterials perform effectively in medical applications.

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2
Q

What are standards?

A

Formal guidelines set by organizations (e.g., ISO, ASTM) that define specifications and test methods to ensure biomaterials are safe, effective, and consistent

Standards play a crucial role in the regulation of biomaterials.

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3
Q

How are standards used in producing and evaluating biomaterials?

A

They guide material selection, fabrication, testing, regulatory approval, and performance evaluation of biomaterials and medical devices

This ensures that products meet safety and efficacy requirements.

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4
Q

What is a first-generation biomaterial device?

A

A device designed to be biologically inert, focusing on mechanical function with minimal interaction with the body (e.g., stainless steel implants)

These devices prioritize stability and durability over biological integration.

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5
Q

What is a second-generation biomaterial device?

A

A device designed to be bioactive or biodegradable, interacting beneficially with tissue (e.g., hydroxyapatite-coated implants, resorbable sutures)

These devices aim to enhance healing and promote integration with the body.

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6
Q

What are six general applications of biomaterials in medicine?

A
  • Orthopedic implants
  • Dental restorations
  • Cardiovascular stents
  • Tissue engineering scaffolds
  • Drug delivery systems
  • Wound dressings

Each application serves a specific role in patient care and treatment.

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7
Q

How is Dacron classified?

A

Synthetic polymer

Commonly used in vascular grafts and other medical applications.

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8
Q

How is poly(methyl methacrylate) classified?

A

Synthetic polymer

Often used in bone cement and intraocular lenses.

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9
Q

How is polyurethane classified?

A

Synthetic polymer

Utilized in various medical devices due to its flexibility and durability.

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10
Q

How is poly-L-lactide classified?

A

Synthetic biodegradable polymer

Frequently used in sutures and drug delivery systems.

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11
Q

How is silicone rubber classified?

A

Synthetic polymer

Known for its biocompatibility and used in implants and prosthetics.

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12
Q

How is collagen classified?

A

Naturally derived polymer

Major component of connective tissues, often used in tissue engineering.

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13
Q

How is hyaluronic acid classified?

A

Naturally derived polymer

Commonly used in dermal fillers and joint lubrication.

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14
Q

How is chitosan classified?

A

Derivative of naturally derived polymer

Derived from chitin, used in wound dressings and drug delivery.

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15
Q

How is heparin classified?

A

Naturally derived polymer

Anticoagulant used in various medical applications.

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16
Q

How is polystyrene classified?

A

Synthetic polymer

Used in various laboratory applications and devices.

17
Q

How is fibrin classified?

A

Naturally derived polymer

Plays a critical role in blood clotting and tissue repair.