Exam 2 Flashcards
(101 cards)
tuberculosis
Reportable, communicable inflammatory destructive disease
extrapulmonary TB sites (6)
bones, spine, kidneys, reproductive organs, CNS, larynx
facts about mycobacterium tuberculosis
aerobic
acid fast
slow growing, sensitive to heat and UV
destroyed by sunlight, heat, and pasteurization
grows inside the body, not outside
risk factors of TB (gender, age, geographical)
alcoholism r/t malnutrition
elderly
homeless
overcrowded
men
children <15
young adults (15-44 with preexisting conditions)
africa, asia, latin america, europe, carribean
BCG vaccine
makes you test + on skin test
need to do chest x-rays or blood test to get accurate result
routes of TB
airborne (droplet)
inhalation of infected droplet nuclei from COUGHING, laughing, sneezing
large droplets settle, small ones are inhaled
treatment of TB
6-12 months
bed rest until no symptoms
isolation until - sputum
sensitization of TB
phagocytes bombard area with bacteria, lymphocytes start inflammatory response and destroy some lung tissue
2-10 weeks after primary infection
patho of TB
inhaled infected droplet deposited in lungs
inflammatory reaction at site
body attempts to phagocytize the wall-off the tubercule
ghon tubercle formed
granuloma in lung tissue
how can dormant TB become active again
mental and physical stress
immunosuppressive drugs
oncology agents
inadequate drug prescription
latent TB
lives and doesn’t grow
doesn’t make you feel sick
CAN’T spread
active TB
grows in the body
makes you feel sick
CAN spread
sputum culture for TB
identify tubercule bacilli
essential to confirm diagnosis
3 specimens on consecutive days
TB skin test
appearance of “wheal” if done properly
read result within 48-72 hours
10mm or more is +
5-9 is doubtful, repeat
for HIV, 5mm or more is +
what to do with TB converters
they are at risk for developing TB
give INH prevention
TB symptoms (8)
Fatigue
Malaise
Anorexia
Weight loss
Chronic productive cough
Night sweats
Advanced state hemoptysis=blood in sputum
Low grade fever in the late afternoon
primary resistance to TB
resistance to 1 or more TB agents with no previous treatment
secondary resistance to TB
resistant to 1+ TB agent, undergoing therapy
multidrug resistance to TB
resistant to 2+ agents (INH and rifampin)
what to give with INH (TB)
vitamin B6
anti TB drugs
INH, rifampin
pyrazinamide
ethambutol (myambutol)
foods to avoid with INH
Tuna
aged cheese
red wine
soy sauce
yeast extract bc it could have histamine (causes side effects [headaches, diaphoresis, etc] and decreased absorption)
nutrition for TB
high protein, calories, and Ca+
iron and vit B6
labs for TB
AST and ALT