Exam #2 Flashcards
(106 cards)
What are vitamins?
- Organic compounds
- Present in minute amounts in natural foodstuffs
- Essential for normal metabolism
- classified as:
* fat soluble
* water soluble
- classified as:
Fat soluble vitamins?
- A, D, K, E
- Important for the body
- Some body storage for A,D,and E
- A and D can be toxic
Water soluble vitamins?
- B and C, Biotin, Choline, and Folacin
- Non-toxic
- No body storage > deficiencies
- Adult ruminants generally do not require dietary source
General function of vitamins?
- Coenzymes of metabolic process
- Affect multiple body systems
- Many water soluble vitamins affect growth
Vitamin A (Retinol) function?
- Required by all animals
- Vision- night vision
- Growth, cell differentiation (lymphocytes), and metabolism
- Bone formation and remodeling
- Reproduction
Vitamin A Deficiencies?
- Night blindness
- Anorexia
- Infection
- Death
Vitamin A toxicities?
- Anorexia
- Dermatitis
- Thinning bones
- Hemorrhage
Vitamin D functions?
- Normal bone mineralization (CA/P)
- Immune system and T-cells
- Conversion and storage in liver
Vitamin D?
- Vitamin D2 (plant) and D3 (animal)
- Sterol precursors in plants and skin require UV light to produce vitamin D
- Dietary sources are fish and dairy products
Vitamin D deficiencies?
- Abnormal skeletal growth/ formation
- Rickets (children)/ Osteomalacia (adult)
- Bowed legs, lameness, sore joints
Vitamin E (tocopherol)?
- Found in most animal tissue, but limited biological activity
- Dietary sources are multigrain cereal, nuts, oils, and leafy greens
- Interactions with minerals and PUFAs
Vitamin E functions?
- Antioxidant- free radical scavengar
- Nuclei acid and protein metabolism
- Cell membrane structure
Vitamin E deficiencies/ toxicity?
- Nutritional muscular dystrophy, white muscle disease and encephalomalacia
- Relatively non-toxic
Vitamin K?
- K1 (phylloquinone)- plant/green veggies
- K2 (menaquinone)- microbial synthesis in GI
- K3 (menadione)- synthetic
Vitamin K function?
- Required for normal blood clotting
- Bone metabolism
Vitamin K deficiencies?
- Caused by antagonists/inhibitors not a true deficiency
- Prolonged clotting time, death
Ex: antibiotics- kill good microbes/ warfarin- kills rats
Vitamin K toxicity?
- Non toxic
- Synthetic form can be toxic to skin and respiratory system
Thiamin (B1)?
- Water soluble
- Present in most foodstuffs- cereal, soy bean, green, leafy hay, animal products (pork)
- Important in citric acid cycle for cellular respiration>energy
- Carbohydrate and lipid metabolism
- Deficiencies: rapid urine loss, enlarged heart, weakness, mental confusion, memory loss, anorexia
Riboflavin (B2)?
- Animal products, greens, veggies
- Sensitive to light
- Deficiencies: usually involves eyes, skin, or nervous system
- Less common due to storage in some cells
- No animals can make it
- Water soluble
Niacin (B3)?
- Meats, yeast, leafy plants
- Electron carriers- give cells energy from food
- Important in DNA damage repair
- Deficiencies: dermatitis, diarrhea, dementia, and death
- Carnivores usually do not have niacin deficiency
- Toxicity: high levels, flushing, itching, nausea, and headache
Pantothenic acid (B5)?
- Required for fatty acid, carbohydrate, and protein metabolism
- Deficiencies: are rare, can be dermatitis, neuromuscular disorder (goose stepping in pigs)
Vitamin B6?
Water soluble
5 different forms
Good sources are meat, liver, cereal grains, and veggies
Requirement change with protein intake, pregnancy, and lactation
Amino acid metabolism- transamination, delaminating, and formation of hormones
Glycogen metabolism-muscle
Deficiencies are rare, malnutrition, convulsions, dermatitis
Caused by damage of food processing
Toxicity is unlikely but can occur in large doses
Vitamin B12?
- Primary source is microbial synthesis – not made by
plants or animals - Dietary sources are animal products – smallest
requirement of any vitamin - Absorbed poorly but stored well in most animals
(except cats) - Important in ruminant metabolism – need a cobalt source
- Helps absorption of nutrients in GI
- Deficiencies: fairly common, anemia, neurological lesions and wasting syndrome,bacterial overgrowth or genetic abnormalities
- Water soluble
Folacin (folic acid)?
- Good sources are leafy vegetables, citrus fruit,
organ meats • - Damaged by heat and light - cooking
- Required for DNA synthesis and red cell production
- Metabolic activity with B12
- Deficiencies: not very common- decreased growth, anemia, birth defects
- Water soluble