Exam #2 Flashcards
(108 cards)
Why Do We Need to Know about Psychopharmacology?:
- Biopsychosocial illnesses: interaction of physical and emotional contributions
- Evidence-based practice: illness management
- Provides important context regarding the client:
* Adherence with treatment
* Side effects; including sharing with the team
* Misperceptions or lack of information about their meds
*OT often assistswith medication management education
one of the first used antipsychotics in psychiatry in the 1950’s, developed as a “tranquilizer
Thorazine
What are the First Generation/Typical Low potency Antipsychotic Medications?
Thorazine
What are the First Generation/Typical High potency Antipsychotic Medications?
Haldol and Prolixin
Typical Antipsychotics: Low Potency AnticholinergicSide Effects:
- Weight gain
- Sedation
- Dry mouth
- Dizziness/confusion
- Tachycardia
- Tardive Dyskinesia: jerky movements, lip-smacking
Typical Antipsychotics: High Potency Side Effects = Acute Extrapyramidal Symptoms (EPS):
- Akathisia (movement, inner restlessness)
- Dystonia (spasms, typically of neck muscles)
- Tremor (non-intention)
- Akinesia
- Bradykinesia- (shuffling gait, drooling, flat affect, stiffness of extremities)
- Muscle Rigidity
This happens when patients are on multiple psychotic medications (e.g., severe muscle rigidity)
Neuroleptic Malignant Syndrome (NMS)
Second Generation/Atypical Antipsychotic Medications
Clozaril
Risperdal
Zyprexa
clients must receive blood workevery week; other effects includesedation, anticholinergic effects, weight gain,orthostatic hypotension
Clozaril
Mood Stabilizers Diagnoses:
- Bipolar I
- Bipolar II
- Cyclothymia
Mood Stabilizers Functions:
- Treat mania
- Treat depression
- Maintain a stable mood
Anticonvulsants/Anti Seizure Medications:
- Depakote
- Tegretol
- Lamictal
Antidepressants “Tricyclic Antidepressants” (TCA)
Anafril and Elavil
Selective Serotonin Reuptake Inhibitors (SSRI):
- Paxil
- Celexa
- Zoloft
- Prozac
- Lexipro
SSRI Indications:
Major Depression
Obsessive-Compulsive Disorder
Panic Disorder
PTSD
Bulimia Nervosa
Premenstrual Dysphoria
Monoamine Oxidase Inhibitors (MAOI):
Nardil and Marplan
Benzodiazepines:
Xanax
Klonopin
Valium
Ativan
Electroconvulsive Therapy (ECT)Indications
Brief electrical stimulation to the brain while the patient is unconscious; generates a seizure; may be unilateral or bilateral (more effective); 8-12 sessions are typical
Indicated for: Bipolar or Depression not responding to medications
Placebo/Nocebo and Belief Effects:
- Placebo: an inert substance or treatmentthatimproves performance
- Nocebo: a negative response based on beliefs (eg: side effects)
- Belief Effects: specific knowledge changes beliefs aboutoutcomes (eg: food, drugs, behaviors
Placebo Effects:
- Placebo effect varies across individuals
- Placebo effect has received a negative connotation that limits its application as a treatment
- Placebos have their greatest impact on the subjective experience of disease (pain,distress), leading to a logical application in mental health
Application of the Placebo Effect in Clinical Practice
- Even the act of seeking treatment may give a sense of empowerment/agency and lead to some relief
- The therapeutic presence of the practitioner may provide support and comfort
- The context (professionalism of the office and the clinician) may support confidence in healing
- A thorough evaluation has been found to influence confidence in healing
- Messaging of the doctor (you will be better soon)
- Placebos can be effective even when the pt knows it is that!
- Has been used recreationally with a high potential for abuse and addiction; very similar to PCP (fencyclidine, Angel Dust)
- Currently being investigated for use with depression, and PTSD; positive effects sometimes called “miraculous”
- May produce long-term changes in the brain
Ketamine
- Naturally occurring psychedelic derived from fungi
- Structurally related to Seratonin
- A recent study found that it is very effective in the treatment of major depression when administered with clinical supervision
Psilocybin (Psychedelic Mushrooms)
Categorization per DSM-5
“Enduring pattern of inner experience and behavior that deviates markedly from the expectations of the individual’s culture, is pervasive and inflexible, has an onset in adolescence or early adulthood, is stable over time and leads to distress or impairment