Exam 2 Flashcards
(209 cards)
Non specific response) 1 line of defense
3rd line of defense
1st Line of Defense: Skin, Mucus membranes, Stomach acid (External)
2nd Line of Defense: Inflammatory response (Cap + permeability)
Specific / Adaptive response) cells:
Phagocytes, Neutrophils, Macrophages & Dendritic cells, Antigen Presenting Cells (Specific Response) “Helps protein & presents flag to T-B cells”
T cells tell B cells to build antigens
Rq cytokines
Interferon:
Made from:
= virus alarm
= infected cell to warn other cells of virus
A chemical that is released from a virus-invaded cell that provides nonspecific resistance to neighboring unaffected cells.
Interferes with viral replication
Acts as a “Whistle Blower”
warning healthy cells to prepare for a viral attack.
Nonspecfic against antigen complement system
Membrane attax complex :
attack membrane to create “Leak channel”
This is another nonspecific defense system against antigens
Activated by two ways:
Classical Complement Pathway: Exposure to antibodies produced against a specific microorganism
Primary mechanism: Alternate Complement Pathway
Exposure to a specific carbohydrate chain found on the surface of a microbe
Humoral Specific Immunity
“Seal Team 6”
Branch of immune system that may occur after reexposure to a particular antigen
Occurs in the extracellular fluid
Permanent defense system against a specific antigen resulting in an attack by antibodies
This involves antibodies!!!!
Degranulation releases (histamine kills)
Natural Immunity aka
Innate Immunity
Genetically predetermine, breast milk passes antigens &/or via placenta
It is present at birth and has no relation no relation to previous exposure to a particular antigen
Artificially Acquired Immunity
Acquired through vaccinations
Dead virus
Designed to give us protection from exposure to an antigen at some point in the future
pruritus
Itching
What effect does the release of histamine have on the vasculature?
Vasodilation.
What type of immunity results from the administration of a vaccine?
Active Acquired immunity.
What is a nonspecific response by the immune system that directly attacks a foreign substance called?
Cellular immunity.
Should a patient experiencing an allergic reaction with no signs of respiratory distress or shock receive epinephrine?
True.
What effect does the release of histamine have on the bronchioles?
Bronchoconstriction.
What is a possible side effect of epinephrine use?
Chest pain.
What do mast cells release after exposure to an allergen in which IgE antibodies are released?
Histamine.
Hymenoptera are
a species of insects, some winged, that sting.
Caring for chem/ burn, its keen to know if its acid or an alkali b/c:
If carbon monoxide is present should also suspect the presence of:
= Alkalis continue to destroy cell membranes via liquefaction necrosis
= Cyanide
Fluid accounts for ~% of the body’s weight, Only ~% of the fluid is contained in our vascular system
= 60% of the body’s weight, Only about 7% of the fluid is contained in our vascular system
If you were administering isotonic crystalloid solutions, how much would move out of the intravascular compartment within 1 hour?
2/3s would move out
Hyperkalemia) 1st line med:
2) One of two 2nd line meds:
3) One of two 2nd line meds:
4) Hospital only med:
5) Hospital only med to poop:
1= Calcium Chloride IV 0.5-1G/3 mins (Stabilizes doesn’t fix)
2= Albuterol 10-20 mg LVN over 15 mins
3= Sodium Bicarb 50 mEq IV mil equivalent
4= Dextrose (25 grams)w/ Insulin IV (10 units)
5= Kayexalate to poop out hyperK via pull interstitial to GI
Hydroxocobalamin:
Adult Dose:
Pedi Dose:
= Suspected cyanide poisoning
= 5 grams IV/IO over 15 minutes. May repeat a 2nd 5 gram dose for a max of 10 grams
= 70 mg/kg IV/IO (max 5 grams)
Alkalotic vs acidotic burns severity
Alkalotic burns > Acidotic burns
Light Burns:
Inhalation Burns:
Toxic inhalation:
Cyanide & carbon monoxide are released via:
= Intense light from arc welder, industrial laser (Ultraviolet keratitis)
= Inhaled gases, heated air, flames, steam; airway & resp/ injury
= Synthetic resins & plastics release toxic gases as they burn
= fake wood & such burning thus Toxic inhalation
1 Alkalis are commonly used as:
2 Acids burns:
3 Alkalis burns:
1= oven and drain cleaners, agricultural fertilizers, and in industry
2= form thick, insoluble mass where they contact T. via coagulation necrosis, limiting burn damage
3= continue destroy cell membranes via liquefaction necrosis, allowing them to penetrate underlying tissue & causing deeper burns