Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

blood banking > exam 2 > Flashcards

exam 2 Flashcards

(64 cards)

Start Studying
1
Q

which blood group system is associated with resistance to malaria?

A

the duffy system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

which antibodies are considered cold agglutinins?

A

I/M/N/P1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

which autoantibody specificity is associated with paroxysmal cold hemoglobinuria and what test that was discussed in lecture is used to detect it?

A

autoanti-P

Donath-Landsteiner Test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

which antigens are destroyed by enzymes and which are enhanced by enzymes?

A

E: Rh except D and Lewis, i, P
D: MNS, duffy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what procedure might help you distinguish between an anti-Fya and an anti-JKa?

A

running fiacin treated panel
enhances JKa
destroys Fya

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

which blood group is produced in the tissues?

A

lewis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is the Mcleod phenotype?

A

absence of Kx Ag

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

which of the antibodies from the other blood group systems discussed for this exam require the antiglobulin test (AHG) for in vitro detection?

A 
kell
duffy
kidd
MN
lutheran
Ss
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is the rarest phenotype of the lutheran system?

A

Lu(a-b-)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

which antigen is X-linked?

A

Xga

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

which antibody is often found in patients with infectious mono, lymphoproliferative disease, and cold agglutinins?

A

anti-i

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

which antibodies are known for causing delayed HTR

A

kidd

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Fy(a-b-) is found primarily in what type of population?

A

african americans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

which antigen is found primarily in South Central and North American Indians and Asians?

A

dia- diego

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which blood group systems are known for showing dosage?

A 
duffy
kidd
MN
Ss
Rh except D
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what is the most common atibody seen in the BB besides ABO and Rh antibodies?

A

anti-K

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

which blood group antigen increases in strength as a newborn grows older?

A

little i to I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

can a patient with blood group Ss be immunized by genotype SS, Ss, or ss?

A

no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

which antigens are actually WBC antigens that are expressed in variable degrees on red blood cells and can cause confusing reactions in serological test?

A

Bg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

which antigens are well-develope at birth, susceptible to enzymes, and generally saline reactive?

A

MN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Name 3 most common antibodies that most likely to react at 37C

A

anti-K
anti-Fya
anti-JKa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

what is the most practical manner for preventing transmission of marlaria for blood transfusions?

A

don’t accept blood from people who have been in a malarial environment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

list the reasons a prospective donor might be permanently deferred for donation of blood products?

A 
IV drug usage
man on man sex
hemophiliac
\+ Ab for HIV
have had viral hep.
clotting disorders/ blood disorders
been to africa
had malaria
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

list the reasons a prospective donor might be temporarily deferred and for how long?

A 
lyme disease
TB
measles, mumps, chicken pox
rabies vaccine
open heart surgery
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
can unused autologous be placed in the general supply and used for another patient other than who it was intended ?
no
26
explain the difference between plasmapheresis, cytapheresis, and plateletpheresis.
plasmapheresis- removal of plasma for donation cytapheresis- collection of cells plateletpheresis- collection of platelets
27
explain the significance of why donor units should be tested for a weak D antigen
D+w should be tested because if weak D is given to a Rh= recipient may elicit an immune response
28
what are the two terms used to refer to AHG that contains both anti-complement and anti-IgG?
polyspecific | broad spectrum
29
a transfusion that replaces approximately a patient's blood volume within a 24 hour period is called what kind of transfusion?
massive transfusion
30
when a physician signs an order for uncrossmatched blood and accepts full responsibility for the transfusion of such products, this is referred to as _____ ____?
emergency release
31
why are homozygous cells used for "ruling out"
incase your dealing with an Ab that shows dosage
32
why are homozygous cells used for "ruling out"
incase your dealing with an Ab that shows dosage
33
why should a patient's serum/plasma for compatibility testing be stored?
incase any concerns arise (HTR)
34
Leukocyte antibodies are usually responsible for what type of transfusion reaction?
febrial
35
which blood bank test detects in vitro sensitization?
IAT
36
explain how the shelf life for blood is determined?
need to be 70% viability post transfusion
37
what is the purpose of the albumin/LISS portion of an antibody screen or crossmatch?
detects IgG Ab's
38
a positive DAT would give you what kind of information on the patient?
in vivo sensitization | RBC are coated with beta or gamma globulins
39
a patient that has had multiple transfusions is most likely to have what type of transfusion reaction?
febrial
40
what does CPDA stand for?
cirtrate- prevents coag. and retards glycolysis phosphate- prevents excessive drop in pH dextrose- used for glycolysis adenine- supplies substrate from which RBC can synthesize ATP
41
how often should a new recipient sample be collected if a series of transfusions are to be administered over a period of several days?
every 3 days
42
inceomplete antibodies are usually Ig_?
G | blocking
43
what does it mean to perform a major crossmatch?
donor cells and recipient plasma
44
cells are "washed" how many times in an antibody screen?
3
45
what is the purpose of washing the cells so many times?
prevents neutralization of AHG by the globulins
46
what is the shelf life of a unit of blood with CPDA-1 as the anticoagulant?
35 days
47
what is the shelf life of a unit of blood with AS-1 as the anticoagulant?
42 days
48
what is therapeutic phlebotomy and why is it used? Name two diseases or conditions in which this might be used
phlebotomy is done for medical reasons to help treat patients symptoms polycythemia hemochromatosis porphyria
49
what type of transfusion is it when a recipient serves as his/her own donor?
autologous
50
what is the "three in, three out" rule? why is it used?
when doing an Ab panel & you suspect a specific Ab, pick 3 botles of cells that are + for the Ag, 3 bottles that are = test against plasma will confirm Ab, must get expeccted results
51
Explain an antibody screen: why and when is it done, what are the stages of the screen, what happens if it is positive, and why is there a control?
why-when: detect clinically sig. Ab before transfusing stages: IS, 37, AHG, CC if +: run a panel why control- check for in vivo sensitization
52
explain TRALI
Transfusion related acute lung injury | caused by rxc to leukocyte Ab in plasma that causes plasma to leak into lungs
53
what is a directed or specific donation?
donated blood used for a specific recipient
54
anti-Dia
diego
55
anti-Sc2
cienna
56
anti-Xga
Xg
57
anti-Cob
colton
58
anti-Ch3
cheeto rogers
59
anti-ge3
gerbich
60
if you do an antibody panel and all cells are positive, including the control, what should be the first thing you should think of may be causing the problem?
warm/cold autoabs
61
why are homozygous cells used for "ruling out"
incase your dealing with an Ab that shows dosage
62
what is the shelf life of a unit of blood with AS-1 as the anticoagulant?
42 days
63
Name 3 most common antibodies that most likely to react at 37C
anti-K anti-D anti-E
64
which antigens are destroyed by enzymes and which are enhanced by enzymes?
E: I, jka, i, p1, rh except D lewis D: MNS, duffy

blood banking (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions