Exam 2 Flashcards

(45 cards)

1
Q

Arteries if the forebrian

A

Anterior cerebral artery—
Middle cerebral artery—- branches of the internal carotid artery
Posterior cerebral artery– (Gets blood from vertebral artery too)

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2
Q

Anterior Cerebral Artery

A

Supplies most of the medial brain

Arches over the corpus callosum

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3
Q

Middle Cerebral Artery

A

Biggest of the 3
Receives 80% of the internal carotid blood flow
Located along the lateral fissure
2 branches: upper (frontal & parietal) and lower ( temporal & occipital)
Supplies blood to 2/3 of the lateral surface
Lateral striated arteries –> lesion pyramidal tract fibers @ internal capsule.

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4
Q

Posterior Cerebral Artery

A
25% of the blood flow comes from the internal carotid artery.
Other 75% comes from vertebral artery
Supplies occipital (medial part) and temporal (inferior part) lobes.
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5
Q

Blood supply to the brain

Vertebral Artery

A

Posterior inferior cerebellar artery- lateral side of the medulla
Anterior spinal artery- ventral and medial aspects of the medulla
Posterior spinal artery- dorsal and medial aspects of the medulla

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6
Q

Blood supply to the brain

Anterior Inferior Cerebellar Artery

A

Supplies the lateral sides of the pons and the inner ear ( artery it the inner ear, labyrinthine artery)

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7
Q

Blood supply to the brain

Pontine

A

Small and striated

Supplies midpons

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8
Q

Blood supply to the brain

Posterior Cerebral

A

Supplies the midbrain

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9
Q

Venous Drainage

Superficial

A

Superior brain-superior sagittal sinus
Middle brain-cavernous sinus
Inferior brain-transverse sinus

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10
Q

Venus Drainage

Deep

A

Great cerebral vein of Galen

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11
Q

Regulation of blood flow

A

Auto-regulation:

  • H+ concentration
  • intraluminar pressure
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12
Q

Meninges

A

Dura mater
Arachnoid membrane
Pia mater

Difference in brain and vertebral canal

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13
Q

Cranial dura

A
Two layers:
Periosteal layer-rich blood supply
Meningeal layer-no vascular supply 
Potential space - located inbetween the two layers
Innervated by Trigeminal nerve c1-c3
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14
Q

Folds of the Meningeal layer

A
Falx Cerebri (longitudinal fissure)
Tentorium Cerebelli
Falx Cerebelli (separating the cerebellum)
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15
Q

Cranial arachnoid

A
Space between dura and arachnoid = subdural space
Arachnoid trabeculae suspends the brain in the CSF
Arachnoid cisterns (found near sinuses, pouches)
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16
Q

Arachnoid granulation

A

CSF passes through the sinuses (helps get ride of old CSF)

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17
Q

Cranial pia

A

Follows contours of the brain (right up against the brain! big space between arachnoid and pia)

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18
Q

Spinal dura

A

One layer
Epidural fat and a plexus of veins separates intro the vertebral periosteum.
Ends at S2
Coccygeal ligament ( filum terminale externa) anchors it to periosteum of cx1 and cx2

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19
Q

Spinal arachnoid

A

Potential subdural space
Trabeculae suspends the spinal cord
Lumbar cistern L2-S2 ( pouch, elongated roots, cauda equina found within

20
Q

Spinal pia

A

Filum terminale
21 (pairs) denticulate ligaments attach to dura from foramen magnum to below tv12
Pia is tightly attached to spinal cord as it is in the brain
Extention-filum terminale interna, has pia and dura inside the dural sac, thicker.

21
Q

Dural sinuses

A
Lined with endothelium
No valves 
Collects blood from brain and emissary veins
Collects CSF from subarachnoid space 
Drains into the internal jugular vein
Carry deoxygenated blood
22
Q

Anterior inferior sinuses

A

Cavernous - sellar tursica,surround pituitary gland
Sphenoparietal - less wing of sphenoid bone
Superior petrosal
Inferior petrosal
Basilar plexus - lies along basic skull, clivous

23
Q

Posterior superior sinuses

A

Superior sagittal
Inferior sagittal Both longitudinal fissure
Straight - runs bw tentorium falx Cerebelli
Transverse - runs in sigmoid sinus
Sigmoid
Confluence - all sinuses come together here, creating a whirlpool. Sucks the blood up by creating a vacuum.

24
Q

Cerebral spinal fluid

A

Formed by the choroid plexus
- 14-35ml per hour
- 800 ml per day
- 150 ml at any given moment
High sodium, potassium, and chloride
Low in protein, lymphocytes, and epitheliod cells
Cushions the brain and removes waste products

25
Ventricles
``` Lateral ventricles (connected through 3rd ven. Through interventricular foramen. 4th bw pons and cerebellum connected to 3rd ven. Through cerebral aqueduct. - anterior horn-frontal lobe - posterior horn-occipital lobe - body-parietal lobe - inferior horn-temporal lobe Interventricular foramen 3rd ventricle Cerebral aqueduct 4th ventricle Central canal ```
26
Sensory unit
Stem fiber (axon) and all of its endings (receptors) Receptive field - territory from which a sensory unit can be excited - not the same as a dermatome!!
27
Dermatome
Strip of skin Innervated by a single spinal nerve | Large amount of overlap by adjacent, small amount of overlap by non-adjacent, more neurons
28
Sensory transduction
The transformation of a stimulus into an electrical signal
29
Rapid adapting receptors phasic
(Bursting) respond quickly and maximally | Will stop responding even when stimulus continues.
30
Slowly adapting receptors tonic
(Continuous) continue to respond to stimulus | Don't react as strongly as fast but stimulus is still there
31
Classification by source
Exteroceptor-stimuli from outside environment Interoceptor-stimuli from internal environment Proprioceptors- position sense (body position, tense on joints and muscles
32
Classification by function (modality)
Nociceptor - pain (noctious) Thermoceptor - temperature Mechanoceptor - "physical deformation"
33
Receptor types | No capsules
``` Free endings - pain - temperature - SA (slow adapting) Follicular ( wraps around follicule, responds to movement of hair) - touch (hair) - RA ( rapid adapting) Merkel cell (hold on to something or pressure) - edge detector - SA Specialized endothelial cells ```
34
Receptor types | Capsules
``` Encapsulated - meissner's RA Ruffini's (deeper, responds to outside forces against you) - shearing (drag) - SA Pacinian (largest receptor visible w/out magnification, deep, several layers of CT) - vibration - RA ```
35
Sensory inflammation of joints, muscles, and skin are...
Integrated in the parietal lobe ( major association of awareness)
36
The brain...
Comprises 2% of the entire body weight Utilizes 20% of the body's O2 17% of the cardiac output goes there.
37
Reticular formation
Net of fibers Phylogenetically old - poorly organized - survival
38
Cellular regions
``` Raphe (seam) - midline (median) --> cells secret serotonin (5-HT) Mangocellular/Gigntocellular (big/really big) - paramedian - surrounding the Raphe - central - center of 1/2 brainstem - medial - center of 1/2 brainstem Parvocellular (small) - lateral ```
39
Neurotransmitter | Acetylcholine
motor system, excitatory - influences movement - peduncleopontine -> found here
40
Neurotransmitters | Noadrenergic/Norepinephrine
Awareness - locus coeruleus -> found here Nucleus of the solitary tract -> found in medulla, sensory area, viseral control Ven trilateral medulla
41
Neurotransmitter | Dopamine
Motivation Decision making Ventral tegmental area -> found here * precurserto norepinephrine
42
Neurotransmitter | Serotonin
Awareness/arousal Mood Decrease pain Raphe nucleus -> found here
43
Goes everywhere, does everything
Afferent, efferent, autonomic, endocrine, awareness, biorhythms, motor, sensory, limbic, association
44
Functions
``` Levels of awareness - ARAS (ascending reticular activation system) > acoustic startle responses > protects from injury by a predator Modulate muscle tone Respiration and cardiac rhythm Pain suppression -> Raphe nucleus helps this Emotion of pain (limbic) ```
45
Reticulospinal tract
Medullary -> lateral! movements of limbs - reticulospinal tract Pontine reticulospinal tract -> medial affect trunk Affect motor neurons * sensory comes in dorsal horn -> blocked by Raphe nucleus