Exam 2 Flashcards

(56 cards)

1
Q

Bacteria in Enterobacteria family

A

SEKSY PECS:

Salmonella, Escherichia, Klebsiella, Shigella, Yersenia, Proteus, Entero, Citro, Serratia

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2
Q

Main Characteristics of Enterobacteriae

A

Gram negative
FACULTATIVE ANAEROBE
Oxidase -
Rod/coccobacilli shape

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3
Q

E. Coli characteristics

A

Gram -
oxidase -
Lactose +
Motile Rods

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4
Q

Cell Associated virulence factors of e. coli

A

Endotoxin
Fimbrial adhesins
Non-Fimbrial adhesins
Capsule

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5
Q

Extra-Cellular virulence factors of e. coli

A

Enterotoxins
Cytotoxins
Siderophores

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6
Q

ENTERIC pathotypes of e. coli (5 acronyms)

A
ETEC
VTEC
EHEC
EPEC
RPEC
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7
Q

Extra-Intestinal Pathotypes of e. coli (4 acronyms)

A

APEC
NTEC (Cattle)
Mastitis-causing (cattle)
MMA

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8
Q

PIG e. coli FACTORS

A

ETEC, EPEC
VTEC
MMA, UTI (cull sow)

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9
Q

CATTLE e. coli FACTORS

A

ETEC, EPEC
EHEC
Mastitis & Septicemia

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10
Q

DOG/CAT e. coli FACTORS

A

cats –> rarely infected

dogs –> UTI

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11
Q

Bacterial Dt in piglets (etiologies)

A

ETEC, EPEC, Salmonella

&others not covered in this section

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12
Q

ETEC in Swine:

1) Ages & Adhesion Factors
2) CS
3) Toxins

A
1)  Neonatal : F5, 6, 41
     2-4 wk:    F4, LT, East1
     Wean:  F4, 18, LT, East 1
2) Watery Diarrhea
3) All enterotoxins (STA, STB, LT, East1)
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13
Q

ETEC in pigs uses which non-fimbrial adhesin (important for vaccines!)

A

AIDA-1

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14
Q

Symptoms of ETEC in pigs

A

Smelly, watery diarrhea
Pigs remain drinking
Dehydration
Diarrhea in older animals: white-grey, less watery

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15
Q

Dx of ETEC in pigs

A

Agglutination test and PCR

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16
Q

Tx of ETEC in pigs

A

Hydration & Antimicrobials

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17
Q

VTEC in pigs

A

Edema disease (F18)
Symptoms appear 3 wk post-weaning
Triggered by stress

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18
Q

Edema Disease affects (organs/systems)

A

Throat, eyelid, lungs, brain

+/- Dt & acute death

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19
Q

Transmission of VTEC

A

Sow –> piglets (will affect more than 1 in litter)

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20
Q

Dx of VTEC

A

Clinical Signs, Culture from fecal, PCR

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21
Q

Tx of VTEC

A

Affected animals: fasting, antimicrobials

Unaffected: antimicrobials

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22
Q

True/False: Breeding pigs without F18 receptor can help control VTEC

A

True: Breeding pigs without F18 receptor can help control VTEC

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23
Q

UTI in pigs (symptoms and tx)

A

Anorexia, hematuria, vaginal exudate, general malaise, hunched back
Tx: Cull sow, hard to treat with antimicrobials

24
Q

Bovine ETEC:

1) AGE
2) Factors
3) CS
4) Toxins

A

1) <3 days
2) F5, 41, 17 & CS31A
3) Watery Diarrhea/ Dehydration
4) STA & STB

25
EPEC/EHEC Bovine: 1) Age 2) Factors 3) CS
1) 1-8 wk 2) EPEC: EAE; EHEC: EAE & VT 3) Mucoid diarrhea +/- blood
26
Septicemia Bovine: 1) Age 2) Factors 3) CS 4) Toxins
1) Neonates (no colostrum, umbilical cord/PO transmission) 2) ExPEC 3) Systemic Effects 4) CNF1 & CNF2
27
Bovine Salmonella (2)
S. typhimurium & S. dublin
28
Swine salmonella (2)
S. typhimurium (&host specific) & S. cholerasius (typhoid)
29
Horses/K9/Feline Salmonella
Non-Host Specific
30
Poultry Salmonella (4)
pullorum gallinarum (typhoid) enteriditis (zoonotic) typhimurium (paratyphoid)
31
Is Klebsiella pneumoniae opportunistic or obligate pathogen?
Opportunistic Pathogen
32
Klebsiella pneumoniae is resistant to which abx
B-lactam (amox) | Tx: with Clavamox!
33
Klebsiella CS (Equine)
Metritis, vaginitis, infertility, abortion, umbilical infections
34
Klesiella CS (K9/Fel)
Pyometra & cystitis
35
Klebsiella CS (bovine)
mastitis
36
Klebsiella CS (primates)
Respiratory infections
37
Yersenia Pestis | Host, Season/Location, CS, Trans
Cats --> Bubonic, pneumonic, septicemic plagues Warm months: SW USA Fever, Respiratory Dz, Lymphadenitis Trans: Flea/Air/Oral
38
Yersenia pseudotuberculosis
Birds --> fatty liver Dz/Rodentiosis Peyers Patches Endotoxin/adhesins in GI/Septicemia
39
Yersenia enterocolitica
Domestic animals: ileitis & gastroenteritis
40
Proteus
Swarming Bacteria | Otitis and Cystitis in dogs
41
Otitis in Dogs Primary Bacteria Secondary Bacteria
1' --> Staph & Yeast (malassezia) | 2' --> Proteus & Pseudomonas
42
Pseudomonas CS 1) Sheep 2) K9/Fel/Rabbit 3) Hamster/G. Pig 4) Horse 5) Cow
1) Sheep: Fleece rot 2) K9/Fel/Rabbit: Dermatitis 3) Hamster: Septicemia/Pneumonia 4) Horses: Keratitis & Metritis/Vaginitis 5) Cow: Mastitis
43
Burkholderia mallei | Species, Clinical Signs, Lesions, Location, Test
* **Reportable & Zoonotic - Equine: Glanders - Orchitis, respiratory dz, skin abscess, lymphadenitis, fever, nasal discharge - Lesions: Nodular --> granulomatous - Asia and South America * *CFT TEST
44
Burkholderia pseudomallei
* *Reportable - Meliodosis: wide host (sheep/goat) - Pseudoglanders: equine - Pyogranulomatous infections
45
Francisella tularensis
``` **Reportable and Zoonotic Contagious! -Reservoir: Lagomorphs and rodents -Intracellular Survival (Fac IC) -Systemic Multi-organ failure -North America ```
46
Taylorella Equigenitalis
Equine CEM (STD) - Acute supparative, sterility, abortions - Self limiting & carriers - Sampling is important!!
47
Brucella (general)
``` **ZOONOTIC (Milk/Contact) & Reportable! STD OBLIGATE PATHOGEN SURVEILLANCE: NO TREATMENT Repro system and joints ```
48
Brucella abortus
Cows Repro/Mastitis Thick peptidoglycan (LPS), no capsule or flagella Dx: Slow Agglutination, then ELISA, then Skin Test!!
49
Brucella Suis
``` Pigs Biovars (different reservoirs) ```
50
Brucella melitesis/ovis
Small ruminants | Similar to abortus (cows)
51
Brucella Canis
Dogs, No O-antigen Sometimes asymptomatic
52
Coliform Bacteria (3)
E. coli Klebsiella Enterobacteriae
53
Benefits of Enterobacteriae
Microbial antagonism Food breakdown Waste processing Vitamin K production
54
Opportunistic Pathogens
Proteus Enterobacteriae Citro Klebsiella
55
Salmonella Phases
SPI 1: Intestinal (non-host specific) | SPI 2: Systemic (host specific/adapted)
56
Is APEC endogenic, exogenic, or both?
Endogenic