Exam 2 Flashcards
(47 cards)
enteroviruses are
small naked RNA viruses
enteroviruses are transmitted via the —- route
oral-fecal
enterovirus family
Picornaviridae
polio viral shedding is —
high
polio enters via the —
mouth
polio incubation is —- in stool and —- in salivia
3-6 weeks, 2 weeks
when polio enters it invades
peyers patches and tonsils
peyers patches are
intestinal lymphoid tissue
polio virus route of entry
- enters via ingestion
- replicates in oro-pharnyx tonsils
- travels to peyers patches and replicates there too
- secondary viremia begin circulating
- get to brain -> encephalitic paralysis, or menages -> meningitis
—-% of polio infections are assymptomatic
95
—% of polio infections are severe
1-2
in severe polio infections polio is transmitted via the — to the —
blood, anterior horn of spinal cord
polio causes — on the — and —
lesions on the brain and spinal cord
in the CNS polio damages —-
motor nuerons
motor neuron destruction by polio manifests clinically as
paralysis
respiratory arrest
death
3 major forms of polio illness
- spinal paralysis
- bulbar
- bulbospinal
polio spinal paralysis is the — common
most
spinal paralysis results from polio virus invasion of the ——
lower spinal cord
polio spinal paralysis can lead to —
asymetric paralysis
bulbar paralysis results from polio invasion of the —-
upper spinal cord and medulla
polio bulbar paralysis can result in
muscle weakness
inability to swallow
use of iron lung or respirator
bulbospinal paralysis results from polio virus invasion of —– and — and can result in
both upper and lower spine and medulla, both types of paralysis
post polio syndrome is a
is a reactivation of polio symptoms 10 to 15 years or more after initial infectoin
course of post polio
paralysis, recovery, stability, post polio
