Exam 2 Flashcards
(95 cards)
tolerance
a person’s diminished response to a drug that is the result of repeated use. physical effect of repeated use of a drug
dependence
physical condition where the body has adapted to the presence of the drug. without the drug the person will experience withdrawals
addiction
chronic, relapsing brain disease characterized by compulsive drug seeking and use, despite harmful consequences. uncontrollable or overwhelming need to use a drug
detox
period of time it takes for body to withdraw from substance you are abusing. takes days to weeks. helps drug abusers safely stop taking drugs while avoiding dangerous withdrawal symptoms
medications used in detox
antidepressants, benzodiazepines, clonidine
CIWA scale
Clinical Institute Withdrawal Assessment for Alcohol, assesses how severe withdrawal symptoms are.
alcohol withdrawal symptoms
increased BP/HR, diaphoresis, GI distress, seizures, hallucinations, memory loss, difficulty concentrating
long term physical problems of alcohol
liver disease, heart problems, muscle weakness, pancreatitis, nerve damage, ulcers, GI bleeding, vitamin deficiency
delirium tremens
severe alcohol withdrawal. global confusion, nightmares, audiitory/visual/tactile hallucinations, sweating high BP/HR, seizures. Death in 1-4% of cases
delirium tremens treatment
reduce environmental stimuli, benzodiazepines, Haldol, fluid, thiamine, folic acid (banana bag)
medications for alcohol addiction
naltrexone, acamprosate, disulfiram
naltrexone (Vivitrol)
for alcohol or opiate addiction. blocks receptors in brain that produce alcohol’s pleasurable effects. Subdues urge to drink or use opiates. Given IM q 4 weeks
acamprosate (Campral)
for alcohol addiction. reduce symptoms of long-lasting withdrawals
disulfiram (Antabuse)
for alcohol addiction. interferes with alcohol breakdown. so acetaldehyde builds up in the body and leads to unpleasant reactions
opiate withdrawal s/s
cramps, diarrhea, runny/stuffy nose, sweating, chills, yawning, muscle pain, nausea/vomiting, anxiety, cravings, trouble sleeping
COWS (Clinical Opiate Withdrawal Scale)
assess severity of opiate withdrawals
medications for opiate withdrawals
clonidine, benzodiazepine, anti-emetics, anti-anxiety, antidepressants
medications for opiate addiction
methadone, buprenorphine, naltrexone
methadone
opiate for opiate addiction.binds to same receptors in brain as heroin and painkillers. suppresses cravings and withdrawal symptoms. clinics dispense it on a daily basis to prevent abuse
buprenorphine (Suboxone)
medication for opiate addiction. partial opiate agonist. less likely to be abused than methadone
cage assessment
5 item screening for alcohol use disorder
anhedonia
common in all types of depressive disorders. loss of interest or pleasure in doing things that you normally enjoy
major depressive disorder criteria
determined with PHQ-9. have to meet at least 5 of 9 criteria and symptoms have to be present for at least a 2 week period. at least one symptom is depressed mood or loss of interest or pleasure
9 criteria for major depressive disorder
depressed mood for most of the days everyday (irritable in children), diminished interest or pleasure in activities, significant wt loss or wt gain (change of more than 5% body wt in a month), insomnia or hypersomnia everday, psychomotor agitation or retardation, fatigue, feel worthless or inappropriate guilt, diminished ability to think/concentrate/indecisiveness, suicidal ideation or recurrent thoughts of death