Exam 2 Flashcards
(36 cards)
Dysphagia
Difficulty in swallowing (subjective)
Causes of dysphagia
Motility dysfunction
Obstructive lesions
Hang up
Heart burn
Esophageal reflux (retrosternal pain, bitter tast)
What motion can instegate heart burn?
Intraabdominap pressure increase: bending over, laying down, heavy lifting and obesity
Odynophagia
Painful swallowing
What is associat d with odynophagia?
Acute esophageal inflammation and ulceration
Sliding hernia
90% of hernia cases
Gastroesophageal junction shifted above hiatus
Manifastation of sliding hernia symptoms occur when?
50% asymtamatic Heart burn (regurgitation) and with increased intraabdominal pressure
Paraesophageal hernia
Rolling hernia
Section of fundus reflected up through hiatus next to esophagus
What are the complications of paraesophageal herniations?
Postprandial bloating
Paraesophageal bleeding
Ulceration
Esophagitis
Contributes to esophageal mucosal injury
The potential risks of esophagitis are?
Erosion
Ulcers/bleeding
Metaplasia
Inflammatory scarring
Barretts espohagus (columnar cell metaplasia), mucosal inflamation, erosion and/or ulcers are associated with chronic or acute esophagitis?
Chronic esophagitis
Whar are the complications of acute and chronic esophagitis?
Ulceration
Dysphagia
Increaed risk of cancer
Morphology of esophageal carcinoma
Mostly squamous cell ca (except Barretts esophagus presenting with adenocarcinoma)
How will carcinoma of the esophagus present?
Mechanical obstruction(solids more so) Hematemsis Poor prognosis (10% make it 5y)
What are the effects of food and drink on Achalasia and carcinoma of the esophagus?
Achalasia- food and drink
Carcinoma- solids more
What do Helicobacter pylori do?
Secretes enzymes that degrade mucin and produces ammonia.
The associated alkalinity stimulates HCL secretion
Is acute gastritis reversable?
Yes
25% of people taking aspirin daily might experiance what over time?
Acute gastritis
The range of superficial g., atropic g. And gastric atrophy reffer to what kind of gastritis?
Chronic gastitis
Autoantibodies against parietal cells and IF (intrensic factor) are what type of gastritis?
Chronic gastritis
Fundic- type A
Fundic-type A is associated with what?
Loss of parietal cells and penicious anemia
Decrease iron absorp.
No ulcers
Increased risk g.ca (10%)
What is a decrease in red blood cells when the body can’t absorb enough vitamin B-12 called?
Pernicious anemia