Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Q4 Women's Health > Exam 2 Cervical Dz > Flashcards

Exam 2 Cervical Dz Flashcards

1
Q

Cervical cells: Inside cervix?

Outside cervix?

A

Inside = columnar epith

Outside = squamous epith

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Cervical Intraepithelial Neoplasia (CIN):

High-grade lesions U seen in what age group?

Invasive CA U seen in what age group?

A

25-35yo

> 40yo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

CIN caused by?

A

HVP:
16/18 = high risk
6/11 = low risk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

CIN risk factors? (6)

A 
HIV/Immunosupp
Smoking
Sluts
Early sex
Long-term oral contr
STds
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

CIN screening initiated?

A

21 regardless of sex activity

EXCEPT <21 HIV+ or chronic suppressive therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

CIN screening F/U? (4)

A

21-29 yo: cytology only Q 3yrs, NO HPV testing

30-65 yo: Cytology + HPV Q 5 yrs

High risk: yearly

HIV: 1st at time of dx, then Q 6 mo x 2, then annually

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Diethylstilbestrol is?

Why do we care?

A

Med given to preggos in 70s

Causes vag/cerv CA, BCA, infert

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Cervical CA screening stopped when?

A 
65yo IF in past 10 yrs:
3 consecutive neg cytology results
OR
2 consec neg co-testing WITH most recent w/i 5 yrs
AND not high risk
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Cervical CA screening for hysterectomy?

A

Stop at removal u/l _hx of CIN2/3,

then annual x 20 yrs regardless of age

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Specimen for cervical cytology must include?

A

endocervical/transformation zone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Cervical Cytology: ASC-US is?

Next step in testing?

A

Atypical cells of u/k significance

Must reflex to HPV DNA:
Neg = N
+ = colposcopy if > 24yo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

ASC-US w/o HPV caused by?

A

Inflamm

Vulvovaginal atrophy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

ASC-US in 21-24yo?

A

repeat cytology at 12 mo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Cervical Cytology: Low-Grade Squamous Intraep Lesion (LSIL) next step in testing?

> 24yo?

21-24yo?

A

Assume HPV DNA ∴ no HVP test until post-meno

Colposcopy

Repeat cytology 12 mo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

LSIL presentation?

A

U similar to CIN I

Enlarged, hyperchromatic nuclei w/ abundant cytoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Cervical Cytology: High-Grade Squamous Intraep Lesions (HSIL) next step testing?

A

Assume HPV

REFER all ages for colposcopy

17
Q

HSIL presentation?

A

U similar to CIN2/3, AIS

Enlarged, hyperchromatic nuclei w/ little or no cytoplasm

18
Q

30-65yo w/ neg Cytology + high risk for HPV, next step testing?

A

HPV DNA typing for 16/18
OR
Repeat co-test in 12 mo (not 5 yrs)

19
Q

Endocervical cells on pap indicate?

A

Only reported if 40+yo
P normal or pathological shedding
Relate to menstrual hx

20
Q

CIN Type 1?

A

Lower 1/3 of epith lining
Seen w/ LSIL
U regress in 12 mo

21
Q

CIN Type 2?

A

Lower 2/3 of epith lining
Seen w/ HSIL
1/2 regress, 20% to Type 3, 5% to invasive CA

22
Q

CIN Type 3?

A

More than 2/3 of epith lining
Seen w/ HSIL
1/2 regress, 40% to CA

23
Q

Colposcopy: Satisfactory when?

Unsatisfactory when?
Next step?

A

Complete visualization of transf zone

Incomp vis of tranf zone ->
Must endocervical curettage

24
Q

CIN tx: Ablation?

F/U? (2)

S/E? (4)

A

NO2 destruction (CIN 1 only)

No sex 4 wks
Healed by 8 wks

Uterine cramping
Profuse, smelly, watery d/c for 4 wks
Cervical stenosis
Less bad preggo outcomes than other tx

25
Q

CIN tx: Excision?

F/U?

S/E?

A

Loop Electrosurgical Excision Procedure (LEEP)

No heavy lifting
No sex 4 wks

Stinky d/c 3 wks
Ist period post is heavier
Obliterated/Incomplete/Stenotic cervix
Pre-term delivery

26
Q

AdenoCA in situ (AIS) is? (5)

A 
Aggressive precursor to cervical adenoCA
U by 37yo
U AGS/HSIL
Endocervical gland involvement w/ atypical columnar epith
U high in canal w/ skip lesions
27
Q

AIS diagnostics?

A

Colpo w/ endocervical curettage and bx

28
Q

AIS tx?

A

Cold knife conization

Hysterectomy

29
Q

Cervical CA?

A

U by 50yo
U HPV 16 SCC (worst)
P HPV 18 AdenoCA

30
Q

Cervical CA presentation? (5)

A 
Asympt
U Abn vag bleeding
Post sex bleeding
Unilat pelvic pain, rad to hip/thigh
Vag d/c
31
Q

Cervical CA tx?

A

From cold knife to hyst w/ chemo/radio

32
Q

Cervical CA f/u? (3)

A

Q 4mo x 2 yrs, then Q 6mo x 3 yrs
Annual pap
Annual CXR x 5 yrs

33
Q

Cervical CA prevention? (5)

A 
HPV vaccine
No sex
Barrier protection
Reg paps
Tx pre-cancers

Q4 Women's Health (20 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions