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Pharmacology 2 > Exam 2 Generic to Brand > Flashcards

Exam 2 Generic to Brand Flashcards

(143 cards)

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1
Q

Phenytoin

A

Dilantin

Sodium channel antagonist

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2
Q

Fosphenytoin

A

Cerebyx

Sodium channel antagonist

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3
Q

Carbamazepine

A

Tegretol

Sodium channel antagonist

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4
Q

Oxcarbazepine

A

Trileptal

Sodium channel antagonist

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5
Q

Eslicarbezpine

A

Aptiom

Sodium channel antagonist

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6
Q

Lamotrigine
- Multiple MOAs (only 1 listed)

A

Lamictal

Sodium channel antagonist

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7
Q

Lacosamide

A

Vimpat

Sodium channel antagonist

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8
Q

Rufinamide

A

Banzel

Sodium channel antagonist

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9
Q

Cenobamate

A

Xcorpi

Sodium channel antagonist

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10
Q

Zonisamide
- 2 MOAs

A

Zonegran

  1. Sodium channel antagonist
  2. T-type Ca2+ channel antagonist
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11
Q

Topiramate
- 3 MOAs

A

Topamax

  1. Sodium channel antagonist
  2. T-type Ca2+ channel antagonist
  3. Enhance GABA neurotransmission
  4. AMPA receptor agonist
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12
Q

Ethosuximide

A

Zarontin

T-type calcium channel antagonist

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13
Q

Valproate
- 2 Brand names
- 3 MOAs

A

Depakote; Depakene

  1. T-type calcium channel antagonist
  2. Enhance GABA neurotransmission
  3. NMDA receptor antagonist
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14
Q

Gabapentin

A

Neurontin

N-type calcium channel blocker

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15
Q

Pregabalin

A

Lyrica

N-type calcium channel antagonist

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16
Q

Benzodiazepines

A

Exam 1 content

Enhance GABA neurotransmission

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17
Q

Barbiturates

A

Exam 1 content

Enhance GABA neurotransmission

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18
Q

Primidone

A

Mysoline

Enhance GABA neurotransmission

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19
Q

Tiagibine

A

Gabitril

Enhance GABA neurotransmission

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20
Q

Vigabatrin

A

Sabril

Enhance GABA neurotransmission

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21
Q

Stiripentol

A

Diacomit

Enhance GABA neurotransmission

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22
Q

Felbamate
- 2 MOAs

A

Felbatol

  1. Enhance GABA neurotransmission
  2. NMDA receptor antagonist
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23
Q

Ganaxolone

A

Ztalmy

Enhance GABA neurotransmission

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24
Q

Phenobarbital
- No brand
- 2 MOAs

A
  1. Barbiturate
  2. AMPA receptor antagonist
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25
Perampanel
Fycompa AMPA receptor antagonist
26
Ezogabine
Potiga Potassium channel stabilizers
27
Levetiracetam
Keppra Reduced neurotransmitter release
28
Brivaracetam
Briviact Reduced neurotransmitter release
29
Cannabidiol
Epidiolex Reduced neurotransmitter release
30
Acamprosate - 3 MOAs
Campral 1. NMDA receptor antagonist 2. GABAa PAM 3. Used in alcohol use disorder
31
Lidocaine - No brand
Local anaesthetic - AMIDE - Intermediate-acting
32
Prilocaine - No brand
Local anaesthetic - AMIDE - Intermediate-acting
33
Mepivacaine - No brand
Local anaesthetic - AMIDE - Intermediate-acting
34
Bupivacaine - No brand
Local anaesthetic - AMIDE - Long-acting
35
Ropivacaine - No brand
Local anaesthetic - AMIDE - Long-acting
36
Dibucaine - No brand
Local anaesthetic - AMIDE - Long-acting
37
Procaine - No brand
Local anaesthetic - ESTER - Short-acting
38
Benzocaine - 2 brand names
Anbesol; Orajel Local anaesthetic - ESTER - Short-acting
39
Cocaine - No brand
Local anaesthetic - ESTER - Intermediate-acting
40
Tetracaine - No brand
Local anaesthetic - ESTER - Long-acting
41
Thiopental
Pentothal Barbiturate - Parenteral anaesthetic - Used for induction phase
42
Methohexital
Brevital Barbiturate - Parenteral anaesthetic - Used for induction phase
43
Propofol
Diprivan Parenteral anaesthetic
44
Fospropofol
Lusedra Parenteral anaesthetic - Prodrug: phosphorylated propofol
45
Etomidate
Amidate Parenteral anaesthetic
46
Ketamine
Ketalar Parenteral anaesthetic - Maintenance anaesthetic
47
Isoflurane
Forane Inhalation anaesthetic - Maintenance anaesthetic
48
Desflurane
Suprane Inhalation anaesthetic - Maintenance anaesthetic
49
Sevoflurane
Ultane Inhalation anaesthetic - Maintenance AND induction
50
Dextroamphetamine + amphetamine - 2 Brand names
Adderall; Mydayis Indirect-acting sympathomimetic - Amphetamine
51
Dextroamphetamine
Dexedrine Indirect-acting sympathomimetic - Amphetamine
52
Methamphetamine
Desoxyn Indirect-acting sympathomimetic - Amphetamine
53
Lisdexamfetamine
Vyvanse Indirect-acting sympathomimetic - Amphetamine
54
Methylphenidate - 2 Brand names
Ritalin; Concerta Indirect-acting sympathomimetic - Methylphenidate
55
Dexmethylphenidate
Focalin Indirect-acting sympathomimetic - Methylphenidate
56
Serdexmethylphenidate + dexmethylphenidate
Azstarys Indirect-acting sympathomimetic - Methylphenidate
57
Benzphetamine
Didrex Indirect-acting sympathomimetic
58
Phendimetrazine
Bontril Indirect-acting sympathomimetic
59
Diethylpropion
Tenuate Indirect-acting sympathomimetic
60
Phentermine - 2 brand names
Adipex; Lomaira Indirect-acting sympathomimetic
61
Phentermine + topiramate
Qsymia Indirect-acting sympathomimetic
62
Atomoxitene
Strattera Indirect-acting sympathomimetic
63
Viloxazine
Qelbree Indirect-acting sympathomimetic
64
Ephedrine
Bronkaid; Primatene tablets Mixed-acting sympathomimetic
65
Solriamfetol
Sunosi DNRI - Treat narcolepsy
66
Modafinil
Provigil Increase 5-HT/orexin brain levels - Treat narcolepsy
67
Armodafinil
Nuvigil Increase 5-HT/orexin brain levels - Treat narcolepsy
68
Sodium oxybate - 2 MOAs - Structurally related to __________
Xyrem 1. GABAb receptor activation 2. GHP receptor activation Structurally related to "GABA"
69
Pitolisant - 2 MOAs
Wakix 1. H3 receptor antagonist 2. H1 receptor agonist
70
Fibanserin
Addyi Serotonin receptor agonist - 5HT1a receptor FULL agonist
71
Imipramine
Tofranil Tricyclic antidepressant
72
Desipramine
Norpramin Tricyclic antidepressant
73
Clomipramine
Anafranil Tricyclic antidepressant
74
Amtriptyline
Elavil Tricyclic antidepressant
75
Nortriptyline
Aventyl; Pamelor Tricyclic antidepressant
76
Doxepin
Silenor Tricyclic antidepressant
77
Protriptyline
Vivactil Tricyclic antidepressant
78
Trimipramine
Surmontil Tricyclic antidepressant
79
Maprotiline
Ludiomil Tricyclic antidepressant
80
Amoxapine
Asendin Tricyclic antidepressant
81
Fluvoxamine
Luvox Selective serotonin reuptake inhibitor
82
Sertraline
Zoloft Selective serotonin reuptake inhibitor
83
Citalopram
Celexa Selective serotonin reuptake inhibitor
84
Paroxetine
Paxil Selective serotonin reuptake inhibitor
85
Escitalopram
Lexapro Selective serotonin reuptake inhibitor
86
Fluoxetine
Prozac Selective serotonin reuptake inhibitor
87
Vortioxetine
Trintellix Selective serotonin reuptake inhibitor
88
Venlafaxine
Effexor Serotonin-norepinephrine reuptake inhibitor
89
Desvenlafaxine
Pristiq Serotonin-norepinephrine reuptake inhibitor
90
Duloxetine
Cymbalta Serotonin-norepinephrine reuptake inhibitor
91
Milnacipran
Savella Serotonin-norepinephrine reuptake inhibitor
92
Levomilnacipran
Fetzima Serotonin-norepinephrine reuptake inhibitor
93
Phenelzine
Nardil Monoamine oxidase inhibitor
94
Tranylcypromine
Parnate Monoamine oxidase inhibitor
95
Selegiline - 2 brands - 2 indications
Emsam Monoamine oxidase inhibitor - Patch for depression MAO-B inhibitor - Anti-parkinsonian
96
Bupropion
Wellbutrin Atypical antidepressant - Inhibits NET and DAT - NO effect on 5-HT
97
Mirtazapine
Remeron Atypical antidepressant - Alpha-2 antagonist
98
Trazodone
Desyrel Atypical antidepressant - Inhibition of NET/SERT
99
Vilazodone
Viibryd Atypical antidepressant - Inhibition of SERT
100
Gepirone
Exxua Atypical antidepressant - 5-HT1a partial agonist - Metabolite is a significant alpha-2 antagonist
101
Esketamine S-enantiomer of _____________
Spravato (nasal spray) Novel antidepressant - NMDA antagonist S-enantiomer of "ketamine" - parenteral anaesthetic
102
Zuranolone
Zurzuvae PAM of GABAa
103
Lithium - 3 possible MOAs - No brand
1. Reduces release of NE from adrenergic neurons 2. Inhibits inositol phosphate pathway 3. Interferes with protein kinases - BPD = treats mania
104
Chlorpromazine - No brand
Traditional antipsychotic D2 receptor antagonist - Limbic -> therapeutic - Basal ganglia -> movement disorders
105
Fluphenazine - No brand
Traditional antipsychotic D2 receptor antagonist - Limbic -> therapeutic - Basal ganglia -> movement disorders
106
Perphenazine - No brand
Traditional antipsychotic D2 receptor antagonist - Limbic -> therapeutic - Basal ganglia -> movement disorders
107
Trifluoperazine - No brand
Traditional antipsychotic D2 receptor antagonist - Limbic -> therapeutic - Basal ganglia -> movement disorders
108
Thiothixene - No brand
Traditional antipsychotic D2 receptor antagonist - Limbic -> therapeutic - Basal ganglia -> movement disorders
109
Haloperidol
Haldol Traditional antipsychotic D2 receptor antagonist - Limbic -> therapeutic - Basal ganglia -> movement disorders
110
Molindone - No brand
Traditional antipsychotic D2 receptor antagonist - Limbic -> therapeutic - Basal ganglia -> movement disorders
111
Loxapine
Traditional antipsychotic D2 receptor antagonist - Limbic -> therapeutic - Basal ganglia -> movement disorders
112
Pimozide
Traditional antipsychotic - Used in Tourette's D2 receptor antagonist - Limbic -> therapeutic - Basal ganglia -> movement disorders
113
Valbenazine
Ingrezza VMAT-2 inhibitor
114
Deutetrabenazine
Austedo XR VMAT-2 inhibitor
115
Aripiprazole
Abilify Atypical antipsychotics - D2 receptor partial agonist
116
Clozapine
Clozaril Atypical antipsychotics - antagonist at D2, D1, D4, alpha-2, and muscarinic receptors
117
Olanzapine
Zyprexa Atypical antipsychotic
118
Olanzapine + Samidorphan
Lybalvi Atypical antipsychotic + MOR antagonist - Helps suppress appetite
119
Quetiapine
Seroquel Atypical antipsychotic
120
Risperidone
Dispersal Atypical antipsychotic
121
Iloperidone
Fanapt Atypical antipsychotic
122
Lurasidone
Latuda Atypical antipsychotic
123
Ziprasidone
Geodon Atypical antipsychotic
124
Paliperidone
Invega Atypical antipsychotic
125
Asenapine
Saphris Atypical antipsychotic
126
Cariprazine
Vraylar
127
Lumateperone
Caplyta
128
Pimavanserin
Nuplazid 5-HT2a recepter inverse agonist
129
Levodopa - No brand - 2 MOAs
1. AAAD inhibitor 2. COMT inhibitor - Anti-parkinsonian
130
Carbidopa
Lodosyn AAAD inhibitor - Anti-parkinsonian
131
Carbidopa + Levodopa
Sinemet AAAD inhibitor - Anti-parkinsonian
132
Tolcapone - No brand
Ongentys COMT inhibitor - Anti-parkinsonian
133
Entacapone
Comtan COMT inhibitor - Anti-parkinsonian
134
Levodopa + Carbidopa + Entacapone
Stalevo COMT/AAAD inhibitor - Anti-parkinsonian
135
Bromocriptine - 2 brands
Parlodel; Cycloset Dopamine receptor agonist - Ergot derivative - Anti-parkinsonian
136
Ropinerole
Requip Dopamine receptor agonist - Anti-parkinsonian
137
Pramipexole
Mirapex Dopamine receptor agonist - Anti-parkinsonian
138
Rotigotine
Neupro Dopamine receptor agonist - Anti-parkinsonian
139
Apomorphine
Apokyn Dopamine receptor agonist - Anti-parkinsonian
140
Rasagiline
Azilect MAO-B inhibitor - Anti-parkinsonian
141
Safinamide
Xadago MAO-B inhibitor - Anti-parkinsonian
142
Trihexyphenidyl - No brand
Muscarinic receptor antagonist - Anti-parkinsonian
143
Benztropine
Muscarinic receptor antagonist - Anti-parkinsonian

Pharmacology 2 (4 decks)

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