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PDA II > Exam 2 NPP > Flashcards

Exam 2 NPP Flashcards

1
Q

Aspirin

A

NSAID

Cox 1 > Cox 2 Inhibitor

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2
Q

Acetaminophen

A

NSAID
Cox 2 Inhibitor
Metabolized to endogenous cannabinoid

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3
Q

Ibuprofen

A

NSAID
OTC = 200mg
Non-specific COX inhibitor

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4
Q

Naproxen

A

NSAID
OTC = 250mg
Non-specific cox inhibitor

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5
Q

Methyl salicylate

A

Topical
Wintergreen oil
Counter irritant- warming effect “swamps” out pain impulses
Metabolized to salicylic acid (COX inhibitor)

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6
Q

Camphor

A

Topical

Counter irritant

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7
Q

Menthol

A

Topical

Counter irritant

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8
Q

Triethanolamine (trolamine) salicylate

A

Topical

Metabolized to salicylate acid

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9
Q

Capsaicin

A

Topical
From hot peppers
TRPV1 agonist - this stimulation “swamps” out pain impulses

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10
Q

Hydrocortisone

A

Topical - SAIDs

Same as cortisol (endogenous steroid)

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11
Q

Triamcinolone, beclomethasone, fluticasome, mometasone

A 
Nasal - SAIDs
Synthetic glucocorticoid/corticosteroid 
Acts of trans. factors 
Decrease pro-inflammatory cytokines
@ high doses - inhibit immune cell growth
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12
Q

Diphenhydramine&doxylamine

Cetirizine

A

Oral Anti-histamine (H1 blocker)

Sedating

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13
Q

Loratadine

Fexofenadine

A

Oral Anti-histamine (H1 blocker)

Non-sedating

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14
Q

Ketotifen

A

Ophthalmic - Anti-histamine (H1B)

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15
Q

Pheniramine

A

Opthalmic/nasal anti-histamine (H1B)

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16
Q

Cromolyn sodium

A

Nasal - Mast cell stabilizer

Stabilize mast cell that release histamine and other inflammatory mediators

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17
Q

Dextromethorphan (DM)

A

Oral Anti-tussive
Opioids structure - its I-isomer is a potent opioid, levorphanal
MOA: blocks the medullary cough center
Gets into CNS

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18
Q

Guafenesin

A

Oral Expectorant

Increases volume and decreases viscosity of bronchial/tracheal secretions

19
Q

Phenylephrine

A

Oral decongestant

Alpha-1-adrenoceptor agonist

20
Q

Pseudoephedrine

A

Oral decongestants
Alpha-1-adrenoceptor agonist
Precursor to meth

21
Q

Naphazoline, oxymetazoline, tetrahydrozoline

A

Topical decongestants

Alpha1-agonist

22
Q

Lidocaine, xylocaine, benzocaine, dyclonine

A

Topical local anesthetic

Blocks pain transmission through fast voltage-gated sodium channels (VGSCs)

23
Q

Neomycin

A

Topical antibiotic, neosporin

Gram (-/+)

24
Q

Polymyxin B

A

Topical antibiotics, neosporin

Gram (-)

25
Q

Bacitracin

A

Topical antibiotic, neosporin

Gram (+)

26
Q

Carbamide Peroxide

A

Topical antibiotic
Broad spectrum antimicrobial
Oxidizing agent

27
Q

Phenol

A

Topical antibiotic

Local anesthetic and antimicrobial

28
Q

Terbinafine

A

Topical antifungal

Tinea pedis/corporis

29
Q

Clotrimazole

A

Topical anti-fungal
Tinea pedis/corporis
Oral/vaginal yeast infections

30
Q

Miconazole

A

Topical anti-fungal
Tinea pedis/corporis/cruris
Vaginal yeast infections

31
Q

Zinc pyrithone

A

Topical antimicrobial

Dandruff/mild psoriasis

32
Q

Permethrin

A

Topical antimicrobial
Insecticide from chrysanthemum
Lice treatment

33
Q

Ranitidine/Famotidine

A

Oral - H2 Blockers

In parietal cells –> decrease stomach acid

34
Q

Omeprazole

A

Oral - Proton Pump Inhibitor

Decrease H+/K+ ATPare in parietal cells, decrease stomach acid

35
Q

Calcium carbonate, magnesium/aluminum hydroxide

A

Antacids

36
Q

Simethicone

A

Anti-gas
Decrease surface tension on gas bubbles
Acts locally in gut

37
Q

Loperamide

A

Anti-diarrheal
U-opioid agonist - decrease GI motility
Little analgesic effect
High doses can cause CNS effects

38
Q

Bismuth subsalicylate (Pepto-Bismol)

A

Antidiarrheal
Bismuth - antibacterial
Subsalicylate - NSAID

39
Q

Fiber, PEG 3350

A

Laxatives

Draws water/add bulk into stool

40
Q

Senna, Bisacodyl

A

Laxative

Stimulant/local irritant

41
Q

Docusate

A

Stool softener

Surfactant - makes stool easier to pass

42
Q

Benzoyl peroxide

A

Acne drug
Peeling agent
Increase skin turnover/decrease bacterial count

43
Q

Salicylic acid

A

Acne drug

Peeling agent, antibacterial, loses pimples

PDA II (3 decks)

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