Exam 2 Practice Flashcards

(54 cards)

1
Q

If you crossed a true-breeding big male with a true-breeding small female, what
distribution of phenotypes would be expected in the F1? what distribution of phenotypes
would be expected in the F2?

A

Parents are XE y and Xe Xe, so F1 will be Xe y (small males) and XE Xe big females.
F2 will be 1 XE y big male : 1 Xe y small male : 1 XE Xe big female : 1 Xe Xe small female

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2
Q

If you crossed a true-breeding small male with a true-breeding big female, what
distribution of phenotypes would be expected in the F1? what distribution of phenotypes
would be expected in the F2?

A

Parents are Xe y and XE XE, so F1 will be XE y (big males) and XE Xe big females.
F2 will be 1 XE y big male : 1 Xe y small male : 1 XE Xe big female : 1 XE XE big female

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3
Q

You are studying a new phenotype in mice. You cross a true-breeding black-eared
mouse with a true-breeding white-eared mouse and you get an all grey-eared F1. If ear
color is controlled by a single gene that exhibits incomplete dominance, what
distribution of phenotypes would you expect in a cross of two grey-eared mice?
E1 E1 (black) x E2 E2 white gives E1 E2 grey

A

Cross of E1 E2 x E1 E2  1 E1 E1 black : 2 E1 E2 grey : 1 E2 E2 white

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4
Q

Name four of the enzymes that are directly involved in DNA replication, and briefly
describe their roles in DNA replication

A

DNA helicase – unwinds double-stranded DNA to provide template for DNA polymerase
DNA primase – creates RNA primer that provides 3’OH for DNA polymerase III
DNA polymerase III – creates daughter strand in complementary antiparallel fashion by
adding nucleotides to 3’ end
DNA polymerase I – removes RNA primer and replaces it with DNA nucleotides
DNA ligase – makes phosphodiester bond between Okazaki fragments
DNA topoisomerase – relieves supercoiling

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5
Q

DNA helicase

A

unwinds double-stranded DNA to provide template for DNA polymerase

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6
Q

DNA Primase

A

creates RNA primer that provides 3’OH for DNA polymerase III

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7
Q

DNA polymerase III

A

creates daughter strand in complementary antiparallel fashion by
adding nucleotides to 3’ end

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8
Q

DNA ligase

A

makes phosphodiester bond between Okazaki fragments

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9
Q

DNA polymerase I

A

removes RNA primer and replaces it with DNA nucleotides

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10
Q

DNA topoisomerase

A

relieves supercoiling

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11
Q

What is a kinase?

A

a protein that adds phosphates to other proteins

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12
Q

What electrical charge does DNA have, and what gives it this charge?

A

negative from the phosphates

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13
Q

There are only 2 alleles for a given gene in a particular population– allele A and
allele a. Allele A is dominant over allele a. This means that

A

In a heterozygote (Aa), the dominant phenotype is expressed

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14
Q

Which of the following statements best describes the results of this experiment? If a
G1 cell is fused with a cell in the S or M stage, the G1 cell will enter the S or M stage
because …

A

..proteins in the S and M cells control the progression to those stages

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15
Q

INcomplete dominance is

A

the heterozygote has a phenotype in between the phenotype of either homozygote

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16
Q

codominance is

A

both alleles are dominant; neither is recessive to each other

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17
Q

Flower color in snapdragons is an example of incomplete dominance

If you cross a red snapdragon with a white snapdragon, you get an F1 that is

If you then cross two F1s you get a phenotypic distribution of

A

incomplete dominance, pink

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18
Q

A botanist has determined that flower color in a new species of orchid is determined by a gene with two alleles, one of which is dominant. The dominant flower color is red.

How many dominant alleles must an orchid possess in order to demonstrate red flowers?

How many recessive alleles must an orchid possess in order to demonstrate white flowers?

What flower color is expected in a heterozygous orchid?

A

1 ; 2; red

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19
Q

The MLH1 gene is located on chromosome 3 in humans and four different alleles have been identified. You examine a cell in G1 of the cell cycle (ie, that has not yet replicated its DNA).

How many copies of the gene are present?

The maximum number of different alleles a single normal individual can have is:

A

2 ; 2

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20
Q

The MLH1 gene is located on chromosome 3 in humans and four different alleles have been identified. You examine a cell in G1 of the cell cycle (ie, that has not yet replicated its DNA).

The minimum number of different alleles a single normal individual can have is:

The maximum number of different alleles a single normal gamete (ie a reproductive cell, a sperm or egg) can have is:

A

1 ; 1

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21
Q

Heterozygous means

A

an individual has two different alleles of a gene

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22
Q

A phenotype is

A

the way something or someone looks

23
Q

An allele of a gene of interest is best described as

A

a variation in the nucleotide sequence of the gene that may or may not result in a detectable phenotype.

24
Q

A gene is

A

A region of the DNA that encodes an enzyme and a Mendelian particle that produces a phenotype

25
null
A DNA sequence that results in no gene product
26
recessive
relationship between an observed trait and the two inherited versions of a gene related to that trait
27
A researcher is studying two different alleles of the gene encoding a human kinase. The wildtype kinase is only active in cells during mitosis; however the mutant allele is active at all stages of the cell cycle. The mutant allele is an example of a __________ allele.
gain-of-function
28
What are the possible genotypes of gametes made by an individual with the genotype Aa?
A, and a
29
What are the possible genotypes of gametes made by an individual with the genotype Bb?
B, and b
30
What fraction of gametes made by an individual with the genotype Bb will have the genotype B?
1/2
31
A small molecule that binds to a receptor and activates it is called a
ligand
32
Homologous chromosomes
have the same genes in the same order, but are not identical
33
Non-homologous chromosomes
have different genes entirely
34
Sister chromatids are
identical to each other
35
Non-sister chromatids
have the same genes in the same order, but are not identical
36
In metaphase of mitosis [ Select ] line up at the metaphase plate
replicated chromosomes
37
In anaphase of mitosis, [ Select ] are pulled apart.
sister chromatids
38
In metaphase of meiosis I _____ line up at the metaphase plate
tetrads
39
CDKS are Kinases True or false
TRUE!
40
Cyclins are Kinases True or false
TRUE!
41
The concentration of a given cyclin changes dramatically as a cell progresses through the cell cycle. True or false
TRUE!
42
In linear electron flow, the electrons start on [ Select ] and end up on [ Select ] .
water, NADP+, forming NADPH
43
In cyclic electron flow, the electrons start on [ Select ] and end up on [ Select ]
photosystem I, photosystem I
44
Linear electron flow produces
O2 ATp and NADPH
45
Cyclic electron flow produces
ATP
46
The substrates for the Calvin Cycle are
ATP CO2 NADPH
47
The products of the Calvin Cycle are
NADP+ ADP glyceraldehyde-3-phosphate
48
The reaction of O2 with RUBISCO is called
photorespiration
49
The reaction of O2 with RUBISCO
releases CO2 from organic matter and doesn't produce ATP
50
This type of receptor has 7 transmembrane helices
G-protein coupled receptor
51
This type of receptor has two individual proteins that combine after they bind their signal molecule
receptor tyrosine kinase
52
This type of receptor functions as a specific pore for transport
gated channel
53
G proteins are regulated by
GTP
54