Exam 2 Trauma Flashcards
(42 cards)
Describe Class I hypovolemic shock?
15% loss; normal VS
Describe Class II hypovolemic shock?
15 – 30% loss; tachycardia, normal SBP
Describe Class III hypovolemic shock?
30 – 40% loss; significant drop in BP & mentation; HR > 120 & delayed cap refill
Describe Class IV hypovolemic shock?
> 40% loss;
hypotensive w/ narrowed pulse pressure;
UO absent;
significant altered mentation
Where is the goal SBP in patients with head injuries?
~ 110 mmHg
What are the two big things we worry about with abdominal trauma patients?
Over-resuscitation with IVF → hemodilution &
abdominal compartment syndrome
What happens in the microcirculatory response in trauma/shock?
The ischemic cells uptake interstitial fluid, become edematous & further depleting intravascular space.
What is the CNS response to shock?
Decreased glucose uptake &
decreased cortical activity & reflexes
What are the kidney/adrenal responses to shock?
Early: maintains GFR.
Late: inability to concentrate urine= ATN
What is the heart’s response to shock?
Dysfunction/ischemia d/t negative inotropes (lactate) &
tachycardia
What is a trauma dose for TXA?
2 gram IVP
When is the best time to give TXA to a trauma victim & when should it not be given anymore?
Within 1hr of trauma.
>3hrs there is an increased chance of bleeding
What is the TXA dose for pediatric traumas?
15mg/kg bolus & then 2mg/kg/hr x 8hrs
What kind of trauma is TXA best suited for?
Best for traumas with non-compressible injuries
Which clotting factors require calcium?
Factor II, VII, & X
How does calcium play a role in clotting?
It helps stabilize fibrinogen & platelets in the development of thrombus
What 2 things decrease citrate metabolism?
Hypothermia & liver injury
Which calcium variant is preferred in the presence of abnormal liver function & why?
Calcium chloride because decreased citrate metabolism by the liver results in slower release of ionized calcium
How much calcium is contained in 10mL of 10% calcium chloride, what about gluconate?
chloride: 270mg
gluconate: 90mg
2 units PRBC drop the iCa2+ to what?
<1.0mmol/L
5 units PRBC drop the iCa2+ to what?
<0.8mmol/L
What worsens coagulopathy?
Acidosis & hypothermia → decreased fibrinogen & platelets
When is calcium chloride given when transfusing whole blood?
Trick question, it is not needed.
What are the contraindications for a REBOA catheter?
Pericardial tamponade,
aortic dissection,
widened mediastinum