Exam 3 Flashcards

(50 cards)

1
Q

Monomers of DNA

A

Adenine, Thymine, Cytosine, Guanine (ATCG)

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2
Q

Shape of DNA

A

Double helix

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3
Q

Nitrogenous bases found in DNA

A

Adenine, Thymine, Cytosine, Guanine
A=T G=C

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4
Q

Bonds holding DNA together

A

Hydrogen bonds

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5
Q

What makes up a nucleotide?

A

Five carbon sugar, phosphate group, nitrogenous base

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6
Q

What is the purpose of DNA replication?

A

Prepare for cell division by creating a copy of the genome

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7
Q

What is semi-conservative?

A

One original strand and one new strand

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8
Q

What are the copied chromosomes held together by?

A

Centromere

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9
Q

Polymerization happens via the

A

dehydration reactions

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10
Q

DNA polymerase works in

A

only one direction

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11
Q

Combines monomers to form polymers

A

Anabolic reaction

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12
Q

Requires energy

A

Endergonic reactions

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13
Q

DNA replication in what direction?

A

5’ to 3’ direction

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14
Q

Prokaryotes have how many origins of replication?

A

One origin

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15
Q

Eukaryotes have how many origins of replication?

A

Many origins

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16
Q

DNA unwinds from the origin of replication to form a

A

replication bubble

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17
Q

Each origin of replication has

A

two replication forks

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18
Q

What is replisome?

A

Molecular machine that does replication

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19
Q

How many replisomes for each origin of replication?

A

Two

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20
Q

What is an FNA primer?

A

Starting nucleotide sequence; gives DNA polymerase a place to start

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21
Q

What is DNA polymerase? DNA polymerase?

A

Main replication enzymes; Adds nucleotides bases in 5’ to 3’ direction (always add to 3’ -OH)

22
Q

Leading strand is built

A

continuously towards replication fork

23
Q

Lagging strand is built

A

discontinuously (in section) away from the replication fork

24
Q

What are the sections of the lagging strand called?

A

Okazaki fragments

25
What are telomeres?
Protective caps at the ends of chromosomes
26
What add telomeres?
Enzyme telmerase
27
Where does telomere elongation occur?
Gametes, stem cells, and cancer cells
28
What is mitosis?
Cell division that creates somatic (body) cells; One division to create two daughter cells
29
What cells are produced in mitosis?
Diploid cells; genetically identical
30
What are the new cells used for in mitosis?
Growth, wound repair, and cell replacement
31
What is meiosis?
cell division that creates gametes (sex cells in animas) (sperm and eggs)
32
What cells are produced in meiosis?
Haploid cells; two rounds of division create four daughter cells; genetically different
33
Gametes in meiosis fuse to form
a 2n zygote during fertilization
34
What is the goal of mitosis?
Produce identical diploid cells for growth and repair
35
Mitosis divides
cytoplasm and other contents to make tow complete cells
36
Mitosis separates
sister chromatids
37
What are the phases of mitosis
Prophase, Prometaphase, Metaphase, Anaphase, Telophase, Cytokinesis
38
Mitosis phrophase
Chromosomes condense into chromatids; start forming spindle apparatus; nuclear envelope breaks down
39
Mitosis Prometaphase
Microtubules of spindle apparatus bind to kinetochores (centromeres) on each sister chromatid
40
Mitosis Metaphase
Sister chromatid pairs line up in the middle of the cell; Driven by microtubule movement
41
Mitosis Anaphase
Sister chromatids are separated/pulled apart; Individual chromosomes pulled to opposite ends; Each pole ends with a full chromosome set
42
Mitosis Telophase
Nuclear envelope reforms; Chromosomes de-condense; Cell now contains two nuclei
43
Mitosis Cytokinesis
Cytoskeleton divides cell into two cells
44
What is the purpose of cell cycle regulation?
Ensure division is needed --> it is energetically expensive; Ensure enough energy to successfully make two cells; prevent replication of damaged cells
45
What is the first checkpoint of the cell cycle regulation?
G1
46
What is the second checkpoint of the cell cycle regulation?
G2
47
What is the third checkpoint of the cell cycle regulation?
Spindle (Mitosis checkpoint)
48
The cells in meiosis produced are genetically
different
49
In meiosis, it creates cells called gametes that are also considered
sperm and egg cells
50
What are the stages of meiosis 1?
Prophase 1, Metaphase 1, Anaphase 1, Telophase 1 and Cytokinesis