Exam 3 Flashcards
(34 cards)
Spirochetes
gram-negative but stain poorly
spiral-shaped
Treponema pallidum
causative agent of syphilis
STI
cannot be cultured on any conventional media
penicillin is the drug of choice
Pinta, Bejel, Yaws
Skin lesions are primary symptoms
Not STD’s
Non-pathogenic Treponemes
Normal flora in oral cavity, genital regions, colon, and rectum
Borrelia recurrentis
relapsing (recurring) fever, body lice/soft tick
Borrelia burgdorferi
lyme disease
transmiteed by nymph stage of hard tick
animal reservoirs: deer and white-footed mice
Leptospira
renal/kidney failure
rat urine
persists in renal tubules of infected humans or animals
contaminated soil, food, and water major mode of transmission
Mycoplasma pneumoniae
walking pneumonia
Mycoplasma hominis
genitourinary/genital infections in females
Ureaplasma
genital infections (male and female)
Chlamydia spp.
obligate intracellular bacteria
Chlamydia trachomatis
conjunctivitis (preventable blindness)
Lymphogranuloma venereum (LGV)
NGU
Chlamydia psittaci
parrot fever
Chlamydia pneumoniae
pneumonia
bronchitis
sinusitis
bacteriostatic
prevents bacterial reproduction
bacteriocidal
kills bacteria
spectrum of activity
how active antibacterial drugs are against bacteria
broth dilution
quantitative (MIC)-labor intensive
Kirby-Bauer diffusion method
standardized
interpretive chart (susceptible, intermediate, or resistant)
synergistic
2 antibiotics combined together enhances bactericidal activity
antagonistic
2 or more antibiotics combined is less effective than one alone
additive
a combination is the same as either one alone
Treats MRSA
What do Vancomycin and Daptomycin treat
Treats Streptococcus pneumonia
50% resistant to natural penicillin
Vancomycin and Daptomycin can be used for penicillin-resistant this