Exam 3 Flashcards
(68 cards)
cell functions
create fuel for the body
manufacture proteins
transport
disposal of waste
benign vs malignant
abnormal growth
abnormal functions
metastasis
benign: BPH, fibroma, lipoma, Meningioma/Brain tumor, Nevi, gastric polyps
malignant: breast, prostate, colon, lung, brain, leukemia, lymphoma, sarcoma
cell cancer mutation risk factors
certain populations (black/african american, latino/hisbpanic, alaska native, american indian, gay/lesbian, less educated/lower socioeconomic status)
age
gender
tobacco use
infections
genetics
radiation
carcinogens
nutrition
physical activity
Cancer Assessment Diagnosis
Visualization (lumps, bumps, bruising, malnourished)
Imaging (xrays, ultrasounds, cat scan, PET scan)
Lab tests (electrolytes, hemogloblin, hematocrit, platelet)
Biopsy (aspirate cells and put under microscope)
Pathology (what kind of cancer cells, start grading and staging)
Cancer Assessment Grading/Staging
size, location, metastasis
TNM method - solid tumors (size, nodes, metastasis)
1 early
2 nearby tissues
3 spread to lymph nodes
4 advanced, distant tissue
Grading:
Gx - can not be assessed
G1 - well differentiated (low grade)
G2 moderate
G3 poor differentiated
G4 undifferentiated (high grade)
Clinical management (treatment) for cancers
surgery
radiation
chemotherapy
hormonal therapy
targeted therapy
biologics
bone marrow/stem cell transplants
cancer treatment side effects
bone marrow suppression (neutropenia, anemia, throbocytopenia)
organ disfunction
fatigue
GI
Mucositis/stomatitis
anorexia
skin reactions
alopecia
mental health changes
neutropenic precautions
strict handwashing
private room
no sick visitors/staff
no live vaccines
avoid procedures
no fresh fruits / vegetables or flowers
leukemia
cancer of blood-forming tissues (bone marrow and lymphatic system) hindering normal function
acute (the worst form, takes over in weeks) vs chronic (years, multiply slowly)
myelogenous vs lymphocytic
Acute Lymphocytic Leukemia (ALL) - children/teens
Acute Myelogenous Leukemia (AML) - adults
Chronic Lymphocytic Leukemia (CLL) - adults
Chronic Myelogenous Leukemia (CML) - older adults
symptoms: fatigue, fever, infections, SOB, weight loss, bone/joint paint, swollen lymph nodes, bruising/bleeding
diagnosis: bone marrow biopsy/cell examination
nursing and interprofessional management: chemo, biologics, targeted therapy, radiation, transplant, CAR T-Cell Therapy
Hodgkin vs Non-Hodgkin Lymphomas
cancer of the lymphatic system, originates from white blood cells
diagnos with PET scan, lymphnode biopsy
stages 1-4
Hodgkin: more rare, less subtypes
Fatigue, fever, wight loss, itching & pain (chest & belly, upper body)
Age: 29-39 or 65 and older
Presence of Reed-Sternberg lymphocytes (oversized WBCs)
More common in upper body
Non-Hodgkin: more common, 70 subtypes
Swollen nodes, pain, cough, dyspnea, fatigue, fever, weight loss, & fullness in stomach
Age: older population
Can occur anywhere in the body
Treatment mostly the same (but surveillance in NON Hodgkin early stages, watch and wait), chemo, targeted therapy, biologics, radiation & transplants
sarcomas
cancer of the bone and connective/soft tissue (fat, muscle, vessels, nerves & tissues around joints and bones)
more common in lower extremities, more common in male at birth, black and hispanic populations
symptoms: lumps, pain, movement issues, weight loss
age: bone child/teen or 65 and older, soft tissue adults
diagnosis: imaging and biopsy
staging: TNM
treatment: surgery (limb salvage), radiation, chemo, targeted therapy, biologics, thermal ablation (chryotherapy)
cancer patients have decreased immune response and are susceptible to ______
sepsis
symptoms: fever, tachycardia, tachypnea, confusion, hypotension and decreased urine output
Upper GI dysfunctions
GERD, gastritis, Peptic Ulcer Disease
Liver dysfunctions
Hepatitis A/B/C, Cirrhosis
GastroEsophageal Reflux Disease (GERD)
chronic symptom of mucosal damage caused by reflux of stomach acid into the lower esophagus
dysfunction of the Lower Esophageal Sphincter (LES), acts like a valve, keeping stomach contents in the stomach
risk factors: obesity, pregnancy (increased abdominal pressure), smoking, hiatal hernia (stomach pushes up through diaphragm), spicy foods, fatty meals, caffine, alcohol
clinical manifestations: heartburn (mimics heart attach), regurgiation, dysphagia, chronic cough, chest pain
complications: Barrett’s esophagus (pre-cancerous condition), esophageal strictures (narrowing due to buildup of scar tissue), reflux pneumonia
treatment/nursing interventions: lifestyle modifications- weight loss, avoid trigger foods, eating smaller meals, elevate HOB
gastritis
inflammation of the stomach lining (gastric mucosa)
acute (rapid onset) or chronic (H. Pylori infection, ongoing exposure)
risk factors: prolonged NSAIDs use, alcohol, poor diet, high stress, autoimmune conditions, bile reflux, advanced age, previous stomach surguries
clinical manifestations: epigastric pain, N/V, anorexia, fullness, hematemisis/melena
complications: peptic ulcers, GI bleed, pernicious anemia (trouble absorbing B12), gastric cancer
treatment: lifestyle mod, avoid alcohol/smoking/irritaitng foods, meds: PPI, antacids, endoscopy
nursing interventions: education, dietary guidance, monitor and assess, stress management, follow up care
Peptic Ulcer Disease
erosion of the GI mucosa from the digestive action of HCI acid and pepsin
most common are gastric and duadnum
excess acid production overwhelms defense mechanisms
risk factors: H Pylori, NSAIDs long term use, stress, smoking, alcohol, coffee, genetics, Ellilson’s syndrome (incrased acid)
clinical manifestations: epigastric pain, N/V, bloating, burping, weight loss
gastric - pain worsens with eating
duadenal - pain better while eating and worse after
complications: bleeding, perforation (peritinitis), obstruction
treatment: lifestyle mod: alcohol, smoking, trigger foods, meds, surgery
nursing interventions: education, monitor & assess, dietary guidance, stress reduction, follow up care
hepatitis
inflammation of the liver
presents as flu-like signs and symptoms
most common are a, b, c
A & E are usually though food/water contamination
B & C usually resulting in chronic disease
B, C, D usually by body fluids
vaccines for hep A & B
hepatitis A
causes: fecal/oral, contaminated food/water, crowded conditions, poor hygiene
prevention: hand hygiene, vaccination
can spread 1-2 weeks before symptoms appear
hepatitis B
spread through sexual contact with infected person, sharing needles (accidental needle sticks in a healthcare workplace) OR from infected mother to fetus
causes: unsafe sex, contaminated needles, mom to baby, exposure to bodily fluids
prevention: vaccine, prevention education
hepatitis C
primarily spread blood to blood
NO VACCINE
causes: drug use, high risk sexual behavior, untested blood products
prevention: education
cirrhosis
end stage liver disease characterized by extensive degeneration and destruction of liver cells
stages leading to cirrhosis: healthy, fatty, fibrosis (scared liver tissue), cirrhosis
risk factors: alcoholism, chronic hepatitis C, overweight, excessive drug use (tylenol)
mimic flu-like signs and symptoms early on
moderate complications: jaundice, pruritis (severe itching), spider angioma (blood vessles), fector hepaticus, bruising and bleeding more easily with impaired clotting
major complications: portal HTN (increased pressure in veins), esophageal varices, ascites, neurologic
_____ can slow cirrhosis in chronic hep C patients
antivirals
cirrhosis damage is _______
irreversible