Exam 3 Flashcards
(245 cards)
The endocrine system controls body activities by…
releasing hormones.
Hormones help regulate…
- extracellular fluid
- metabolism
- contraction of cardiac & smooth muscle
- glandular secretion
- some immune functions
- growth and development
- reproduction
Which glands have primary function as an endocrine gland?
- Pituitary gland
- thyroid gland
- parathyroid gland
- adrenal gland
- pineal gland
What has secondary function as an endocrine gland?
- hypothalamus
- thymus
- pancreas
- ovaries
- testes
- kidneys
- stomach
- liver
- small intestine
- skin
- heart
- placenta
- adipose tissue
Although hormones travel throughout the body…
they only affect specific target cells (with specific protein or glycoprotein receptors)
What are endocrines?
Hormones that travel in the blood and act on distant target cells.
What are local hormones?
Hormones that act locally without entering the bloodstream.
What are the 2 types of local hormones?
Paracrines & Autocrines
Paracrines act on…
neighboring cells
Autocrines act on…
themselves (the cells that secreted them)
What types of hormones are lipid soluble?
- Steroids
- Thyroid hormones
- nitric oxide
What are the 3 groups of water soluble hormones?
- Amines
- Peptides, proteins, and glycoproteins
- Eicosanoids
What hormones are amines?
- epinephrine
- norepinephrine
- melatonin
- seratonin
What hormones fall in the group of peptides, proteins and glycoproteins?
- insulin
- growth hormone
- ADH
What hormones are eicosanoids?
- prostaglandins
- leukotrienes
Lipid soluble hormones bind to and activate receptors…
within the cell (not on the surface)
Receptors activated by lipid soluble proteins…
alter gene expression resulting in formation of new proteins.
Water soluble hormones alter cell functions by …
activating plasma membrane receptors, setting of a cascade of events inside the cell.
The cascade of events initiated by a water soluble hormone is called…
the messenger system
What is the first messenger in the messenger system?
The hormone that binds to the cell membrane receptor.
What is the second messenger in the messenger system?
A chemical activated inside the target cell.
What is a common second messenger?
Cyclic AMP (cAMP)
Which hormones increase cAMP levels?
ADH, TSH, ACTH, glucagon, & epinephrine
Which hormones decrease cAMP levels?
growth hormone inhibiting hormone (somatostatin)