Exam 3 Flashcards

(142 cards)

1
Q

carcinogenesis

A

malignant transformation involving 3 step process of initiation, promotion, and progression

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2
Q

Initiation

A

carcinogen damages DNA by changing a specific gene

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3
Q

Promotion

A

process by which carcinogens are subsequently introduced

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4
Q

Progression

A

process by which tumors go from bad to worse

  • neovascularization
  • invasion
  • metastasis
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5
Q

Proto-oncogenes

A

Turn on cell growth

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6
Q

Anti-oncogenes

A

Turn off cell growth

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7
Q

Hypertrophy

A

cell growth that causes tissue to increase in size by enlarging each cell

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8
Q

Hyperplasia

A

growth that causes tissue to increase in size by increasing the number of cells

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9
Q

Metaplasia

A

conversion from the normal pattern of differentiation if one type of cell into another type of cell not normal for that tissue

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10
Q

Dysplasia

A

an alteration in the shape, size, appearance, and distribution of cell

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11
Q

Anaplasia

A

disorganized, irregular cells that have no structure and have loss of differentiation; the result is almost always malignant

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12
Q

Neoplasia

A

new or continued cell growth not needed for normal development or replacement of dead and damaged tissues.

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13
Q

ANC levels that increase the risk for infection

A

1,500 risk for infection increases; 500 severe risk for infection

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14
Q

Nadir

A

lowest level of ANC after chemotherapy

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15
Q

Collaborative mgmt of sepsis and DIC

A
  • prevention is best measure
  • IV antibiotic therapy
  • Anticoagulants
  • cryoprecipitated clotting factors
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16
Q

Collaborative mgmt of SIADH

A
  • fluid restriction
  • increased sodium intake
  • demeclocycline
  • treating the underlying cancer
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17
Q

Signs and symptoms of superior vena cava syndrome

A

edema of face, Stoke’s sign, edema of arms and hands, dyspnea, erythema, cough, hoarseness

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18
Q

Antimetabolites

A

“imposter” metabolites used to fool cancer cells into using them for cellular reactions will impair division

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19
Q

Antitumor antibiotics

A

damage cell DNA and interrupt DNA and RNA synthesis

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20
Q

Alkylating agents

A

inhibit DNA and RNA synthesis, and therefore cell division, by tightly binding DNA strands together

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21
Q

Antimitotic agents

A

Interfere with the formation of microtubules necessary for mitosis, comes from vinca plant

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22
Q

Factors delaying wound healing

A
  • Poor nutrition
  • Tissue perfusion and oxygenation
  • excessive wound drainage
  • Diseases
  • Age
  • Medications
  • Infection
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23
Q

Braden scores

A
  • 12 or less is high risk for development of ulcer

- 18 at risk for ulcer

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24
Q

PUSH score

A

0 is healed; 17 not healed

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25
Diabetes insipidus comes from where?
posterior pituitary gland
26
The nurse is conducting a staff in-service on childhood endocrine disorders. Diabetes insipidus is a disorder of:
posterior pituitary
27
The nurse is caring for a preschool child with suspected diabetes insipidus. Which clinical manifestation should the nurse expect to observe?
Polyuria and polydipsia
28
A nasal spray of desmopressin acetate (DDAVP) is used to treat which disorder?
Diabetes insipidus
29
Type 1 diabetes
Characterized by progressive destruction of beta cells, usually leading to an absolute insulin deficiency
30
Type 1 diabetes onset
peak onset between 11-13; childhood and adolescence
31
Hallmark signs of type 1 diabetes
weight loss, polydipsia, polyuria, polyphagia, weakness and fatigue, ketoacidosis
32
Preparing insulin
1. air into intermediate 2. air in regular 3. draw up regular 4. draw up intermediate
33
Rapid insulin onset, peak, and duration
Onset: 10-30 minutes Peak: 30 minutes to 3 hours Duration: 3-5 hours
34
Short acting insulin onset, peak, and duration
Onset: 30-60 minutes Peak: 2-5 hours Duration: 5-8 hours
35
Intermediate acting insulin onset, peak, and duration
Onset: 1-4 hours Peak: 4-12 hours Duration: 10-16
36
Long acting insulin onset, peak, duration
Onset: 2-4 hours Peak: None Duration: 24 hours
37
Type 2 diabetes characteristics
- Insulin resistance - Pancreas decreased ability to produce insulin - Inappropriate glucose production from liver - Alteration in production of hormones and adipokines - Individuals with metabolic syndrome at increased risk for type 2 diabetes
38
A1C normal level
less than or equal to 6.5%; greater than 7% is not good
39
Sulfonylureas
stimulates beta cells, increases number of insulin receptors, decreases amount of glucose produced by liver
40
Biguanides
decreases amount of glucose produced by liver, increases glucose used by muscles Ex: metformin
41
Alpha-glucosidase inhibitors
inhibits CHO absorption in small intesting; starch blockers | Ex: Acarbose
42
Thiazolidinediones
decreaes insulin resistance, inhibits glucose production in liver Ex: Actos
43
Meglitinides
stimulates short burst of insulin release from pancreas
44
Dipeptidyl peptidase (DDP)
slows the activation of incretin hormones
45
Parents of a toddler with hypopituitarism ask the nurse, “What can we expect with this condition?” The nurse should respond with which statement?
Skeletal proportions are normal for age
46
A child with hypopituitarism is being started in growth hormone (GH) therapy. Nursing considerations should be based on which knowledge?
Replacement therapy requires daily subcutaneous injections
47
A child with growth hormone (GH) deficiency is receiving GH therapy. When is the best time for the GH to be administered?
At bedtime
48
An adolescent is being seen in the clinic for evaluation of acromegaly. The nurse understands that which occurs with acromegaly?
There is excess growth hormone (GH) after the closure of the epiphyseal plates
49
A child will start treatment for precocious puberty. The nurse recognizes that this will involve the injection of which synthetic medication?
Luteinizing hormone-releasing hormone
50
Hypophysectomy is done through what?
Transphenoidal surgery
51
Hypophysectomy is done for what?
anterior pituitary tumor
52
The nurse is admitting a toddler with the diagnosis of juvenile hypothyroidism. Which is a common clinical manifestation of this disorder?
Dry skin
53
A goiter is an enlargement or hypertrophy of which gland?
Thyroid
54
Exophthalmos (protruding eyeballs) may occur in children with:
Hyperthyroidism
55
The nurse is teaching the parents of a child who is receiving methimazole (Tapazole) for the treatment of hyperthyroidism (Graves disease). Which statement made by the parent indicates a correct understanding of the teaching?
"If my child develops a sore throat and fever, I should contact the physician immediately."
56
Which clinical manifestation may occur in the child who is receiving too much methimazole (Tapazole) for the treatment of hyperthyroidism (Graves disease)?
Lethargy and somnolence
57
A child with hypoparathyroidism is receiving vitamin D therapy. The parents should be advised to watch for which sign of vitamin D toxicity?
Weakness and lassitude
58
Glucocorticoids, mineralocorticoids, and sex steroids are secreted by the:
adrenal cortex
59
Chronic adrenocortical insufficiency is also referred to as:
Addison disease
60
A neonate born with ambiguous genitalia is diagnosed with congenital adrenogenital hyperplasia. Therapeutic management includes administration of:
cortisone
61
The parents of a neonate with adrenogenital hyperplasia tell the nurse that they are afraid to have any more children. The nurse should explain which statement about adrenogenital hyperplasia?
Genetic counseling is indicated
62
Which is characteristic of the immune­mediated type 1 diabetes mellitus?
Age at onset is usually younger than 20 years
63
Which is considered a cardinal sign of diabetes mellitus?
Frequent urination
64
Hyperglycemia associated with diabetic ketoacidosis is defined as a blood glucose measurement equal to or greater than _____ mg/dl.
200
65
Type 1 diabetes mellitus is suspected in an adolescent. Which clinical manifestation may be present?
Poor wound healing
66
A parent asks the nurse why self­monitoring of blood glucose is being recommended for her child with diabetes. The nurse should base the explanation on which knowledge?
Children are better able to manage the diabetes
67
The parent of a child with diabetes mellitus asks the nurse when urine testing will be necessary. The nurse should explain that urine testing is necessary for which?
Ketonuria is suspected
68
The parents of a child who has just been diagnosed with type 1 diabetes ask about exercise. Which should the nurse explain about exercise in type 1 diabetes?
Extra snacks are needed before exercise
69
A child eats some sugar cubes after experiencing symptoms of hypoglycemia. This rapid­releasing sugar should be followed by:
complex carbohydrate and protein
70
The nurse is caring for an 8­year­old child with type 1 diabetes. The nurse should teach the child to monitor for which manifestation of hypoglycemia?
Shaky feeling and dizziness
71
The nurse is caring for an 11­year­old boy who has recently been diagnosed with diabetes. Which should be included in the teaching plan for daily injections?
He is old enough to give most of his own injections
72
The nurse is discussing with a child and family the various sites used for insulin injections. Which site usually has the fastest rate of absorption?
Abdomen
73
To help the adolescent deal with diabetes, the nurse must consider which characteristic of adolescence?
Need to be perfect and similar to peers
74
The nurse is implementing care for a school­age child admitted to the pediatric intensive care in diabetic ketoacidosis (DKA). Which prescribed intervention should the nurse implement first?
Begin 0.9% saline solution intravenously as prescribed
75
The nurse should teach parents of a preschool child with type 1 diabetes that which can raise the blood glucose level?
steroids
76
A nurse is reviewing the laboratory results on a school­age child with hypoparathyroidism. Which results are consistent with this condition?
Decreased serum calcium
77
Nursing care of a child diagnosed with a syndrome of inappropriate ADH should include which of the following? (Select all that apply.)
- weigh daily | - restrict fluids
78
The nurse should expect to assess which clinical manifestations in an adolescent with Cushing syndrome? (Select all that apply.)
- hyperglycemia - cushingoid features - susceptibility to infections
79
A nurse is planning care for a school­age child with type 1 diabetes. Which insulin preparations are rapid and short acting? (Select all that apply.)
- NovoLog | - Novolin R
80
A nurse is planning interventions for a toddler with juvenile hypothyroidism. Which interventions should the nurse plan to implement for this child? (Select all that apply.)
- Moisturizer for dry skin | - Implementation of thyroxine therapy
81
The nurse is caring for a school­age child with hyperthyroidism (Graves disease). Which clinical manifestations should the nurse monitor that may indicate a thyroid storm? (Select all that apply.)
- Hyperthermia - Tachycardia - Vomiting
82
The clinic nurse is reviewing hemoglobin A1c levels on several children with type 1 diabetes. Hemoglobin A1c levels of less than _____ % is a goal for children with type 1 diabetes. (Record your answer in a whole number.)
7
83
The nurse is taking care of a 7­year­old child with a skin rash called a papule. Which clinical finding should the nurse expect to assess with this type of skin rash?
A lesion that is elevated, palpable, firm and circumscribed; less than 1 cm in diameter
84
The nurse is teaching nursing students about childhood skin lesions. Which is an elevated, circumscribed skin lesion that is less than 1 cm in diameter and filled with serous fluid?
Vesicle
85
The nurse is taking care of a 2­year­old child with a macule skin lesion. Which clinical finding should the nurse expect to assess with this type of lesion?
Flat, brown mole less than 1 cm in diameter
86
A school­age child falls on the playground and has a small laceration on the forearm. The school nurse should do which to cleanse the wound?
Wash wound gently with mild soap and water for several minutes
87
A child steps on a nail and sustains a puncture wound of the foot. Which is the most appropriate method for cleansing this wound?
Soak foot in warm water and soap
88
Which nursing consideration is important when caring for a child with impetigo contagiosa?
Carefully wash hands and maintain cleanliness when caring for an infected child
89
The nurse is caring for a 5­year­old child with impetigo contagiosa. The parents ask the nurse what will happen to their child’s skin after the infection has subsided and healed. Which answer should the nurse give?
There will be no scarring
90
Cellulitis is often caused by:
Streptococcus or Staphylococcus organisms
91
The nurse is conducting a staff in­service on appearance of childhood skin conditions. Lymphangitis (“streaking”) is frequently seen in which condition?
Cellulitis
92
The nurse should expect to assess which causative agent in a child with warts?
Virus
93
The nurse should implement which prescribed treatment for a child with warts?
Local destruction
94
Herpes zoster is caused by the varicella virus and has an affinity for:
Posterior root ganglia and posterior horn of the spinal cord
95
The nurse is taking care of a 7­year­old child with herpes simplex virus (type 1 or 2). Which prescribed medication should the nurse expect to be included in the treatment plan?
Oral antiviral agent
96
Tinea capitis (ringworm), frequently found in schoolchildren, is caused by a(n):
fungus
97
The nurse is caring for a school­age child with a tinea capitis (ringworm) infection. The nurse should expect that therapeutic management for this child includes:
administering oral griseofulvin
98
Parents tell the nurse that their child keeps scratching the areas where he has poison ivy. The nurse’s response should be based on which knowledge?
Scratching the lesions may cause them to become secondarily infected
99
The nurse is taking care of a child with scabies. Which primary clinical manifestation should the nurse expect to assess with this disease?
Pruritus
100
Which is usually the only symptom of pediculosis capitis (head lice)?
Itching
101
The nurse is talking to the parents of a child with pediculosis capitis. Which should the nurse include when explaining how to manage pediculosis capitis?
“You will need to remove nits with an extra­fine tooth comb or tweezers.”
102
The management of a child who has just been stung by a bee or wasp should include the application of:
cool compress
103
A father calls the clinic nurse because his 2­year­old child was bitten by a black widow spider. The nurse should advise which to the father?
Take child to emergency department
104
A mother calls the emergency department nurse because her child was stung by a scorpion. The nurse should recommend:
keeping the child quiet and coming to the emergency department
105
Rocky Mountain spotted fever is caused by the bite of a:
tick
106
The school nurse is conducting a class for school­age children on Lyme disease. Which is characteristic of Lyme disease?
caused by a spirochete that enters the skin through a tick bite
107
The nurse is examining 12­month­old Amy, who was brought to the clinic for persistent diaper rash. The nurse finds perianal inflammation with satellite lesions that cross the inguinal folds. This is most likely caused by:
Candida albicans
108
The nurse is teaching a class on preventing diaper rash in newborns to a group of new parents. Which statement made by a parent indicates a correct understanding of the teaching?
“If my infant’s buttocks become slightly red, I will expose the skin to air.”
109
Which prescribed treatment should the nurse plan to implement for a child with psoriasis?
Tar and exposure to sunlight and ultraviolet light
110
Atopic dermatitis (eczema) in the infant is:
associate with allergy with a hereditary tendency
111
Nursing care of the infant with atopic dermatitis focuses on:
preventing infection
112
Tretinoin (Retin­A) is a topical agent commonly used to treat acne. Nursing considerations with this drug should include:
explaining that medication should not be applied until at least 20 to 30 minutes after washing.
113
When is isotretinoin (Accutane) indicated for the treatment of acne during adolescence?
The acne has not responded to other treatments
114
A child experiences frostbite of the fingers after prolonged exposure to the cold. Which intervention should the nurse implement first?
Rapid rewarming of the fingers by placing in warm water
115
Which best describes a full­thickness (third­degree) burn?
Destruction of all layers of skin evident with extension into subcutaneous tissue
116
A child is admitted with extensive burns. The nurse notes that there are burns on the child’s lips and singed nasal hairs. The nurse should suspect that the child has a(n):
inhalation injury
117
Which explains physiologically the edema formation that occurs with burns?
Increased capillary permeability
118
The most immediate threat to life in children with thermal injuries is:
shock
119
After the acute stage and during the healing process, the primary complication from burn injury is:
infection
120
An adolescent girl is cooking on a gas stove when her bathrobe catches fire. Her father smothers the flames with a rug and calls an ambulance. She has sustained major burns over much of her body. Which is important in her immediate care?
Remove her burned clothing and jewelry
121
A young child has sustained a minor burn to the foot. Which is recommended for treatment of a minor burn?
Cleanse the wound with a mild soap and tepid water
122
A toddler sustains a minor burn on the hand from hot coffee. Which is the first action the nurse should recommend in treating this burn?
Hold burned area under cool running water
123
A parent of a child with major burns asks the nurse why a high­calorie and high­protein diet is prescribed. Which response should the nurse make?
The diet will avoid protein breakdown
124
Fentanyl and midazolam (Versed) are given before débridement of a child’s burn wounds. Which is the rationale for administration of these medications?
Provide pain relief
125
Nitrous oxide is being administered to a child with extensive burn injuries. Which is the purpose of this medication?
Provide anesthesia
126
Hydrotherapy is required to treat a child with extensive partial­thickness burn wounds. Which is the primary purpose of hydrotherapy?
Debride the wounds
127
A child with extensive burns requires débridement. The nurse should anticipate which priority goal related to this procedure?
Reduce pain
128
Biologic dressings are applied to a child with partial­thickness burns of both legs. Which nursing intervention should be implemented?
Observing wounds for signs of infection
129
Which is one of the first signs of overwhelming sepsis in a child with burn injuries?
Disorientation
130
Which is an effective strategy to reduce the stress of burn dressing procedures?
Give child as many choices as possible
131
Which is an important consideration for the nurse when changing dressings and applying topical medication to a child’s abdomen and leg burns?
Wash hands and forearms before and after dressing change
132
The family of a 4­month­old infant will be vacationing at the beach. Which should the nurse teach the family about exposure of the infant to the sun?
Keep the infant in total shade at all times
133
A nurse is teaching a parent of an infant about treatment of seborrhea dermatitis (cradle cap). Which should the nurse include in the instructions?
Shampoo every day with an antiseborrheic shampoo
134
The nurse is teaching parents of toddlers about animal safety. Which should be included in the teaching session?
Teach your toddler not to disturb an animal that is eating
135
A school nurse assesses a case of tinea capitis (ringworm) on a 6­year­old child. Which figure depicts the characteristic lesion of tinea capitis?
picture with the scalp
136
Where do the lesions of atopic dermatitis (eczema) most commonly occur in the infant? (Select all that apply.)
- cheeks - extensor surfuces of arms and legs - trunk - scalp
137
The nurse is talking to a parent of an infant with severe atopic dermatitis (eczema) . Which response(s) should the nurse reinforce with the parent? (Select all that apply. )
- “You will need to keep your infant’s skin well hydrated by using a mild soap in the bath.” - “You will need to prevent your baby from scratching the area by using a mild antihistamine.” - “You should apply an emollient to the skin immediately after a bath.”
138
Which should the nurse include when teaching parents about preventing childhood burn injuries? (Select all that apply.)
- keep hot liquids out of reach - baby proof electrical outlets - test water temperature before placing your child in the tub bath
139
The community health nurse is teaching parents about prevention of the spread and reoccurrence of pediculosis (head lice). Which should the nurse include in the teaching session? (Select all that apply.)
- Dryclean nonwashable items - Boil combs and brushes for 10 minutes - Discourage sharing of personal items
140
A nurse is caring for a 5-­year ­old child with a major burn. The health care provider has written a prescription to notify the health care provider if urine output falls to or below 2 ml/kg/hr. The child weighs 55 lb. The nurse should notify the health care provider if the milliliters of urine output is at or below _____ for an hour. (Record your answer in a whole number.)
50
141
Top male cancer
``` Prostate Lung and bronchus Colin and rectum Urinary bladder Melanoma of the skin ```
142
Top 5 female cancers
``` Breast Lung and Bronchus Colon and rectum Uterine corpus Thyroid ```