EXAM 3 Flashcards
(262 cards)
1
Q
What is the trade name for Atorvastatin?
A
Lipitor
2
Q
What is the therapeutic class for Atorvastatin?
A
Antihyperlipidemic
3
Q
What is the therapeutic use for Atorvastatin?
A
Reduction of LDL & cholesterol
4
Q
What is the pharm class of Atorvastatin?
A
HMG-CoA reductase inhibitor
5
Q
What is the MOA of Atorvastatin?
A
Reduction of synthesis of cholesterol in liver; increase in LDL receptors in liver
6
Q
What is the trade name for Cholestyramine?
A
Questran
7
Q
What is the therapeutic class for Cholestyramine?
A
Antihyperlipidemic
8
Q
What is the therapeutic use for Cholestyramine?
A
Reduction of cholesterol
9
Q
What is the pharm class of Cholestyramine?
A
Bile acid resin
10
Q
What is the MOA of Cholestyramine?
A
Prevent enterohepatic recycling of bile acids, increasing elimination of cholesterol
11
Q
What is the trade name for Ezetimibe?
A
Zetia
12
Q
What is the therapeutic class for Ezetimibe?
A
Antihyperlipidemia
13
Q
What is the therapeutic use for Ezetimibe?
A
Adjunct to therapy with statin to reduce LDL
14
Q
What is the pharm class of Ezetimibe?
A
Cholesterol absorption inhibitor
15
Q
What is the MOA of Ezetimibe?
A
Inhibits intestinal absorption of cholesterol
16
Q
What is the trade name for Gemfibrozil?
A
Lopid
17
Q
What is the therapeutic class for Gemfibrozil?
A
Antihyperlipidemic
18
Q
What is the therapeutic use for Gemfibrozil?
A
To reduce triglycerides & VLDL, and increase HDL
19
Q
What is the pharm class of Gemfibrozil?
A
Fibric acid agent
20
Q
What is the MOA of Gemfibrozil?
A
Decreases conversion of cholesterol to VLDL, and increase lipoprotein lipase synthesis
21
Q
What is the trade name for Nicotinic acid (vitamin B)?
A
Niaspan
22
Q
What is the therapeutic class for Nicotinic acid (vitamin B)?
A
Antihyperlipidemic
23
Q
What is the therapeutic use for Nicotinic acid (vitamin B)?
A
Treatment of hyperlipidemia not responding to diet & weight loss; to slow progression of coronary artery disease (CAD) when combined with a bile acid sequestrant
24
Q
What is the pharm class of Nicotinic acid (vitamin B)?
A
Other antihyperlipidemics; vitamin
25
What is the MOA of Nicotinic acid (vitamin B)?
Inhibits release of free fatty acids from adipose tissue, increases rate of triglyceride removal from plasma, reduces LDL & triglyceride levels and increases HDL levels
26
What is the trade name for Doxazosin?
Cardura
27
What is the therapeutic class for Doxazosin?
Antihypertensive, treatment of benign prostatic hyperplasia (BPH)
28
What is the therapeutic use for Doxazosin?
To treat hypertension; treatment of BPH
29
What is the pharm class of Doxazosin?
Alpha1-adrenergic blocker
30
What is the MOA of Doxazosin?
Selective for Alpha1-adrenergic receptors, thus causes vasodilation; also cause relaxation of smooth muscle around prostate gland
31
What is the trade name for Enalapril?
Vasotec
32
What is the therapeutic class for Enalapril?
Antihypertensive, treatment of heart failure
33
What is the therapeutic use for Enalapril?
To treat hypertension; treatment of heart failure
34
What is the pharm class of Enalapril?
ACE inhibitor
35
What is the MOA of Enalapril?
Inhibits conversion of angiotensin I to angiotensin II, a vasoconstrictor, and decreases production of aldosterone, resulting in decreased renal sodium reabsorption
36
What is the trade name for Hydralazine?
Apresoline
37
What is the therapeutic class for Hydralazine?
Antihypertensive, treatment of heart failure
38
What is the therapeutic use for Hydralazine?
Treatment of hypertension that is refractory to other antihypertensives
39
What is the pharm class of Hydralazine?
Direct-acting vasodilator
40
What is the MOA of Hydralazine?
Relaxes arterial smooth muscle by inhibiting IP3 formation
41
What is the trade name for Hydrochlorothiazide?
Microzide
42
What is the therapeutic class for Hydrochlorothiazide?
Antihypertensive, treatment of edema
43
What is the therapeutic use for Hydrochlorothiazide?
To treat hypertension with edema; also approved to treat heart failure, and nephrotic syndrome
44
What is the pharm class of Hydrochlorothiazide?
Thiazide diuretic
45
What is the MOA of Hydrochlorothiazide?
Decreases reabsorption of sodium in the kidney by inhibiting the sodium/chloride cotransporter in the distal tubule of the nephron
46
What is the trade name for Nifedipine?
Adalat
47
What is the therapeutic class for Nifedipine?
Antihypertensive, treatment of angina
48
What is the therapeutic use for Nifedipine?
To treat hypertension and variant or vasospastic angina
49
What is the pharm class of Nifedipine?
Calcium channel blocker
50
What is the MOA of Nifedipine?
Selectively blocks calcium channels in myocardial muscle and vascular smooth muscle
51
What is the trade name for Atenolol?
Tenormin
52
What is the therapeutic class for Atenolol?
Antianginal; antihypertensive; beta-blocker
53
What is the therapeutic use for Atenolol?
Treatment of heart failure, hypertension, angina, and MI.
54
What is the pharm class of Atenolol?
Selective beta1-adrenergic blocker
55
What is the MOA of Atenolol?
Selectively blocks beta1- adrenergic receptors in the heart; slows heart rate and reduces contractility.
56
What is the trade name for Losartan?
Cozaar
57
What is the therapeutic class for Losartan?
Antihypertensive
58
What is the therapeutic use for Losartan?
Used alone or in combination therapy for treatment of hypertension; treatment of diabetic nephropathy.
59
What is the pharm class of Losartan?
Angiotensin II-receptor blocker (ARB)
60
What is the MOA of Losartan?
Selectively blocks angiotensin II receptors; blocks vasoconstriction, and release of aldosterone due to interruption of the renin-angiotensin-aldosterone system.
61
What is the trade name for Propranolol?
Inderal
62
What is the therapeutic class for Propranolol?
Class II antidysrhythmic; antihypertensive
63
What is the therapeutic use for Propranolol?
Treatment of cardiac dysrhythmia, hypertension, angina, and migraine headaches, and for prevention of MI.
64
What is the pharm class of Propranolol?
Beta-adrenergic antagonist (nonselective)
65
What is the MOA of Propranolol?
Nonselective beta- adrenergic blocker, affecting beta1 receptors in the heart, and beta2 receptors in pulmonary and vascular smooth muscle; reduces heart rate, slows myocardial conduction velocity, and lowers bp
66
What is the trade name for Digoxin?
Digitek
67
What is the therapeutic class for Digoxin?
Positive inotrope
68
What is the therapeutic use for Digoxin?
To increase cardiac output, alleviating symptoms of heart failure & improving exercise tolerance
69
What is the pharm class of Digoxin?
Cardiac glycoside
70
What is the MOA of Digoxin?
Inhibits sodium-potassium ATPase, and increases intracellular calcium concentrations in cardiac cells
71
What is the trade name for Furosemide?
Lasiz
72
What is the therapeutic class for Furosemide?
Antihypertensive, treatment of edema & heart failure
73
What is the therapeutic use for Furosemide?
Treatment of acute heart failure, to remove edema, especially when cardiac output & renal flow are severely diminished
74
What is the pharm class of Furosemide?
Loop diuretic
75
What is the MOA of Furosemide?
Prevents renal reabsorption of sodium & chloride in the loop of Henle
76
What is the trade name for Lisinopril?
Prinivil
77
What is the therapeutic class for Lisinopril?
Antihypertensive, treatment of heart failure
78
What is the therapeutic use for Lisinopril?
Treatment of hypertension, heart failure, and improvement of survival in patients when administered within 24 hours after MI
79
What is the pharm class of Lisinopril?
ACE inhibitor
80
What is the MOA of Lisinopril?
Inhibits angiotensin converting enzyme, decreases aldosterone secretion
81
What is the trade name for Metoprolol?
Lopressor
82
What is the therapeutic class for Metoprolol?
Antihypertensive, beta-blocker
83
What is the therapeutic use for Metoprolol?
To slow progression of HF, & to significantly reduce the long-term consequences of HF
84
What is the pharm class of Metoprolol?
Selective beta1-adrenergic antagonist
85
What is the MOA of Metoprolol?
Decreases cardiac workload by reduction of heart rate (due to selective blockade of beta1-adrenergic receptors)
86
What is the trade name for Milrinone?
Primacor
87
What is the therapeutic class for Milrinone?
Positive inotrope
88
What is the therapeutic use for Milrinone?
Short-term treatment of advanced HF, to immediately increase myocardial contractility & cardiac output
89
What is the pharm class of Milrinone?
Phosphodiesterase inhibitor
90
What is the MOA of Milrinone?
Inhibits degradation of cAMP by phosphodiesterase
91
What is the therapeutic use for Atenolol in terms of being an antianginal?
To reduce/prevent angina pain by lowering myocardial oxygen demand
92
What is the MOA of Atenolol in terms of being an antianginal?
Reduces heart rate & contractility, which decreases myocardial oxygen demand
93
What is the trade name of Diltiazem?
Cardizem
94
What is the therapeutic class for Diltiazem?
Antihypertensive, antianginal, antidysrhythmic
95
What is the therapeutic use for Diltiazem?
To treat angina, by increasing oxygen delivery to myocardium & reducing oxygen demand by myocardium
96
What is the pharm class of Diltiazem?
Calcium channel blocker
97
What is the MOA of Diltiazem?
Dilates both coronary & peripheral vessels, which increases oxygen delivery to myocardium & decreases cardiac workload
98
What is the trade name of Nitroglycerin?
Nitrostat
99
What is the therapeutic class of Nitroglycerin?
Antianginal
100
What is the therapeutic use of Nitroglycerin?
To rapidly terminate angina pain, or to prevent angina pain
101
What is the pharm class of Nitroglycerin?
Organic nitrate, vasodilator
102
What is the MOA of Nitroglycerin?
Dilates veins, reducing venous return, & dilates coronary arteries, providing more oxygen to myocardium
103
What is the trade name of Reteplase?
Retavase
104
What is the therapeutic class of Reteplase?
Thrombolytic (clot-buster)
105
What is the therapeutic use of Reteplase?
Immediate treatment of myocardial infarction (MI), to restore coronary blood flow
106
What is the pharm class of Reteplase?
Thrombolytic
107
What is the MOA of Reteplase?
Cleaves plasminogen, forming plasmin, which degrades fibrin matrix of thrombus
108
What is the trade name of Amiodarone?
Cordarone
109
What is the therapeutic class of Amiodarone?
Class III antidysrhythmic
110
What is the therapeutic use of Amiodarone?
Treatment of severe atrial & ventricular dysrhythmias; treatment of resistant ventricular tachycardia; treatment of atrial dysrhythmias is patients with HF
111
What is the pharm class of Amiodarone?
Potassium channel blocker
112
What is the MOA of Amiodarone?
Blocks potassium channels & to a smaller degree sodium channels; slows repolarization, increases duration of action potential, prolongs refractory period
113
What is the trade name for Procainamide?
Procanbid
114
What is the therapeutic class of Procainamide?
Class Ia antidysrhythmic
115
What is the therapeutic use of Procainamide?
Treatment of many types of atrial & ventricular dysrhythmias
116
What is the pharm class for Procainamide?
Sodium channel blocker
117
What is the MOA of Procainamide?
Blocks sodium channels in myocardium, reducing automaticity & slowing conduction velocity of action potentials; increases duration of action potential, delays repolarization, prolongs refractory period
118
What is the trade name for Propranolol?
Inderal
119
What is the therapeutic class of Propranolol?
Class II antidysrhythmic
120
What is the therapeutic use of Propranolol?
Treatment of atrial flutter & fibrillation, tachydysrhythmia, ventricular dysrhythmias
121
What is the pharm class for Propranolol?
Non-selective beta-adrenergic antagonist
122
What is the MOA of Propranolol?
Reduces heart rate, slows myocardial conduction velocity, reduces automaticity, prolongs refractory period; reduces excessive sympathetic stimulation of heart
123
What is the trade name for Verapamil?
Calan
124
What is the therapeutic class of Verapamil?
Class IV antidysrhythmic, antianginal
125
What is the therapeutic use of Verapamil?
Treatment of paroxysmal supraventricular tachycardia, supraventricular tachydysrhythmia
126
What is the pharm class of Verapamil?
Calcium channel blocker
127
What is the MOA of Verapamil?
Slows conduction velocity, prolongs refractory period; decreases contractility; reduces blood pressure & cardiac workload; dilates coronary arteries
128
What is the trade name for Alteplase?
Activase
129
What is the therapeutic class of Alteplase?
Thrombolytic (clot-buster)
130
What is the therapeutic use of Alteplase?
Treatment of CVA due to thrombus; restore the patency of IV catheters (off-label use)
131
What is the pharm class of Alteplase?
Thrombolytic
132
What is the MOA of Alteplase?
Synthetic form of tissue plasminogen activator (TPA); activates plasminogen, which forms plasmin; plasmin degrades fibrin mesh in clots
133
What is the trade name for Aminocaproic acid?
Amicar
134
What is the therapeutic class of Aminocaproic acid?
Clot stabilizer
135
What is the therapeutic use of Aminocaproic acid?
Reduction in post-operative bleeding; treatment of excessive bleeding due to prematurely dissolving clots
136
What is the pharm class of Aminocaproic acid?
Hemostatic/antifibrinolytic
137
What is the MOA of Aminocaproic acid?
Inactivates plasminogen, reducing the dissolution of clots
138
What is the trade name for Clopidogrel?
Plavix
139
What is the therapeutic class of Clopidogrel?
Antiplatelet drug
140
What is the therapeutic use of Clopidogrel?
Prevention of thromboembolic events in patients with recent history of MI, CVA, or peripheral artery disease; thrombi prophylaxis in patients with unstable angina, & those receiving vascular bypass procedures & angioplasty
141
What is the pharm class of Clopidogrel?
ADP receptor blocker
142
What is the MOA of Clopidogrel?
Directly inhibits ADP binding to its receptor, prolonging bleeding time & inhibiting platelet aggregation
143
What is the trade name for Heparin?
Heplock
144
What is the therapeutic class of Heparin?
Anticoagulant (parenteral)
145
What is the therapeutic use of Heparin?
To prevent the enlargement of existing clots & formation or new clots
146
What is the pharm class of Heparin?
Indirect thrombin inhibitor
147
What is the MOA of Heparin?
Binds to antithrombin III, inactivating several clotting factors, & inhibits thrombin activity
148
What is the trade name for Warfarin?
Coumadin
149
What is the therapeutic class of Warfarin?
Anticoagulant (oral)
150
What is the therapeutic use of Warfarin?
To treat cerebrovascular accidents (CVA), myocardial infarction (MI), deep vein thrombosis (DVT), & pulmonary embolism; prevention of thromboembolic events in high-risk patients; prevention of clot formation in patients with indwelling central venous catheters or prosthetic heart valves
151
What is the pharm class of Warfarin?
Vitamin K antagonist
152
What is the MOA of Warfarin?
Inhibits action of vitamin K, reducing synthesis of clotting factors II, VII, IX, & X
153
What is the trade name for Cyanocobalamin?
Calomist
154
What is the therapeutic class of Cyanocobalamin?
Anti-anemia drug
155
What is the therapeutic use of Cyanocobalamin?
Treatment of vitamin B12 deficiency anemia, pernicious anemia, megaloblastic anemia
156
What is the pharm class of Cyanocobalamin?
Vitamin supplement
157
What is the MOA of Cyanocobalamin?
Participates in DNA synthesis; necessary for erythropoiesis
158
What is the trade name of Epoetin alpha?
Epogen
159
What is the therapeutic class of Epoetin alpha?
Anti-anemia drug
160
What is the therapeutic use of Epoetin alpha?
Treatment of anemia in patients with chronic renal failure, & in patients with anemia caused by deficiency in erythropoiesis
161
What is the pharm class of Epoetin alpha?
Hemotopoietic growth factor, erythropoietin
162
What is the MOA of Epoetin alpha?
Stimulates maturation of erythrocyte stem cells into erythrocytes
163
What is the trade name for Ferrous sulfate?
Feosol
164
What is the therapeutic class of Ferrous sulfate?
Anti-anemia drug
165
What is the therapeutic use of Ferrous sulfate?
Treatment of iron deficiency anemia
166
What is the pharm class of Ferrous sulfate?
Iron supplement
167
What is the MOA of Ferrous sulfate?
Participates in production of hemaglobin
168
What is the trade name for Filgrastim?
Neupogen
169
What is the therapeutic class of Filgrastim?
Drug for increasing neutrophil production
170
What is the therapeutic use of Filgrastim?
Treatment of neutropenia
171
What is the pharm class of Filgrastim?
Myeloid colony stimulating factor
172
What is the MOA of Filgrastim?
Increases neutrophil production in bone marrow; enhances phagocytic & cytotoxic function of existing neutrophils; stimulates granulocyte & macrophage proliferation & differentiation
173
What is the trade name for Dopamine?
Dopastat
174
What is the therapeutic class of Dopamine?
Drug for shock, inotrope
175
What is the therapeutic use of Dopamine?
To treat shock; at low doses-treatment of hypovolemic & cardiogenic shock; at high doses-to increase blood pressure
176
What is the pharm class of Dopamine?
Nonselective adrenergic agonist; inotrope
177
What is the MOA of Dopamine?
At low doses, it selectively stimulates dopamine receptors (kidney), causing renal vasodilation & increased renal blood flow; at high doses it increases the production of norepinephrine (DA is a precursor for NE), causing increased total peripheral resistance & blood pressure
178
What is the trade name for Epinephrine?
Adrenalin
179
What is the therapeutic class of Epinephrine?
Drug for shock, inotrope, vasopressor agent
180
What is the therapeutic use of Epinephrine?
Treatment of anaphylactic shock, increases blood pressure, causes bronchodilation
181
What is the pharm class of Epinephrine?
Nonselective adrenergic agonist; vasopressor
182
What is the MOA of Epinephrine?
Stimulates alpha-adrenergic receptors, increasing peripheral resistance (blood pressure); stimulates beta1-adrenergic receptors, increasing cardiac output; stimulates beta2-adrernrgic receptors, dilating airways
183
What is the trade name for Norepinephrine?
Levophed
184
What is the therapeutic class of Norepinephrine?
Drug for shock, inotrope, vasopressor agent
185
What is the therapeutic use of Norepinephrine?
Treatment of acute shock (significantly reduces mortality); treatment of cardiac arrest
186
What is the pharm class of Norepinephrine?
Nonselective adrenergic agonist; vasopressor
187
What is the MOA of Norepinephrine?
Sympathomimetic; binds to both alpha- & beta1-adrenergic receptors, constricts blood vessels & increases heart rate
188
What is the trade name for Normal serum albumin?
Albuminar
189
What is the therapeutic class of Normal serum albumin?
Fluid replacement agent
190
What is the therapeutic use of Normal serum albumin?
To restore plasma volume in hypovolemic shock
191
What is the pharm class of Normal serum albumin?
Blood product, colloid
192
What is the MOA of Normal serum albumin?
Increases plasma oncotic pressure, drawing water from tissues into plasma
193
What is the trade name for Acetazolamide?
Diamox
194
What is the therapeutic class of Acetazolamide?
Drug for glaucoma
195
What is the therapeutic use of Acetazolamide?
To reduce intraocular pressure in patients with glaucoma
196
What is the pharm class of Acetazolamide?
Carbonic anhydrase inhibitor, diuretic
197
What is the MOA of Acetazolamide?
Inhibits carbonic anhydrase in renal proximal tubule, decreases sodium reabsorption & proton secretion
198
What is the trade name for Chlorothiazide?
Diuril
199
What is the therapeutic class for Chlorothiazide?
Antihypertensive, treatment of edema & heart failure
200
What is the therapeutic use for Chlorothiazide?
To treat mild hypertension, typically in combination with other antihypertensives; to treat fluid retention due to heart failure & other causes
201
What is the pharm class of Chlorothiazide?
Thiazide diuretic
202
What is the MOA of Chlorothiazide?
Decreases reabsorption of sodium in the kidney by inhibiting the sodium/chloride cotransporter in the distal tubule of the nephron
203
What is the trade name for Furosemide?
Lasix
204
What is the therapeutic class of Furosemide?
Antihypertensive, treatment of edema & heart failure
205
What is the therapeutic use of Furosemide?
Treatment of acute heart failure, to remove edema, especially when cardiac output & renal flow are severely diminished
206
What is the pharm class of Furosemide?
Loop diuretic
207
What is the MOA of Furosemide?
Prevents renal reabsorption of sodium & chloride in the loop of Henle
208
What is the trade name for Mannitol?
Osmitrol
209
What is the therapeutic class of Mannitol?
Miscellaneous diuretic
210
What is the therapeutic use of Mannitol?
Treatment of elevated intracranial pressure; maintain urine flow in patients with acute renal failure, or during prolonged surgery
211
What is the pharm class of Mannitol?
Osmotic diuretic
212
What is the MOA of Mannitol?
Filtered by not reabsorbed in renal glomerulus, increases osmotic Starling force in Bowman's capsule, increases net filtration of water out of plasma
213
What is the trade name for Spironolactone?
Aldactone
214
What is the therapeutic class of Spironolactone?
Antihypertensive, treatment of edema
215
What is the therapeutic use of Spironolactone?
Treatment of hypertension, typically in combination with other antihypertensives
216
What is the pharm class of Spironolactone?
Potassium-sparing diuretic; aldosterone antagonist
217
What is the MOA of Spironolactone?
Blocks aldosterone receptors in collecting duct of nephron; inhibits sodium-potassium exchange, increasing sodium excretion, but decreasing potassium excretion
218
What is the trade name for Aldesleukin?
Proleukin
219
What is the therapeutic class of Aldesleukin?
Immunostimulant
220
What is the therapeutic use of Aldesleukin?
To treat renal cell carcinoma; treat metastatic melanomas
221
What is the pharm class of Aldesleukin?
Interleukin
222
What is the MOA of Aldesleukin?
Activates cytotoxic T cells, increases cytokines & platelet count
223
What is the trade name for Cyclosporine?
Neoral
224
What is the therapeutic class of Cyclosporine?
Immunosupressant
225
What is therapeutic use of Cyclosporine?
To prevent tissue rejection in patients receiving transplant; also used to treat severe cases of ulcerative colitis & Crohn's disease
226
What is the pharm class of Cyclosporine?
Calcineurin inhibitor
227
What is the MOA of Cyclosporine?
Inhibits helper T cells
228
What is the trade name for Interferon alfa-2b?
Intron-A
229
What is the therapeutic class of Interferon alfa-2b?
Immunostimulant
230
What is the therapeutic use of Interferon alfa-2b?
To treat hairy cell leukemia, malignant melanoma, non-Hodgkin's lymphoma, AIDS-related Kaposi's sarcoma, human papilloma virus, chronic hepatitis virus B & C
231
What is the pharm class of Interferon alfa-2b?
Interferon, biologic response modifier
232
What is the MOA of Interferon alfa-2b?
Attach to infected cells & signal them to secrete antiviral proteins; increase phagocytosis & enhance cytotoxic T cell activity
233
What is the trade name for Muromonab-CD3?
Orthoclone OKT3
234
What is the therapeutic class for Muromonab-CD3?
Immunosupressant
235
What is the therapeutic use for Muromonab-CD3?
To prevent renal transplant rejection; treat steroid-resistant rejection of heart & liver transplants in adults
236
What is the pharm class for Muromonab-CD3?
Monoclonal antibody
237
What is the MOA of Muromonab-CD3?
Monoclonal antibody to T cell antigen
238
What is the trade name for Acetaminophen?
Tylenol
239
What is the therapeutic class of Acetaminophen?
Antipyretic, analgesic
240
What is the therapeutic use of Acetaminophen?
Treatment of fever in children; relief of mild to moderate pain when aspirin is contraindicated
241
What is the pharm class of Acetaminophen?
Centrally acting COX inhibitor
242
What is the MOA of Acetaminophen?
Inhibits prostaglandin synthesis in CNS
243
What is the trade name for Aspirin?
Bayer aspirin
244
What is therapeutic class of Aspirin?
Antiinflammatory, analgesic, antipyretic
245
What is the therapeutic use of Aspirin?
Treatment of fever, pain, and mild inflammatory conditions
246
What is the pharm class of Aspirin?
Salicylate
247
What is the MOA of Aspirin?
Inhibits prostaglandin synthesis by cyclooxygenase 1 & 2
248
What is the trade name for Celecoxib?
Celebrex
249
What is the therapeutic class of Celecoxib ?
Antiinflammatory, analgesic
250
What is the therapeutic use of Celecoxib?
Treatment of acute & chronic arthritis in adults
251
What is the pharm class of Celecoxib?
COX-2 inhibitor, NSAID
252
What is the MOA of Celecoxib?
Inhibits prostaglandin synthesis by cyclooxygenase-2
253
What is the trade name for Ibuprofen?
Advil
254
What is the therapeutic class for Ibuprofen?
Antiinflammatory, analgesic, antipyretic
255
What is the therapeutic use of Ibuprofen?
Treatment of mild to moderate pain, fever, & inflammation
256
What is the pharm class for Ibuprofen?
NSAID
257
What is the MOA of Ibuprofen?
Inhibits prostaglandin synthesis by cyclooxygenase 1 & 2
258
What is the trade name for Prednisone?
Sterapred
259
What is the therapeutic class for Prednisone?
Antiinflammatory
260
What is the therapeutic use of Prednisone?
Treatment of severe inflammation; treatment of neoplasia, asthma, arthritis, corticosteroid deficiency
261
What is the pharm class of Prednisone?
Glucocorticoid
262
What is the MOA of Prednisone?
Inhibits phospholipase A2, which produces arachidonate, a precursor of inflammatory prostaglandins
