Exam 3 Flashcards

(57 cards)

1
Q

Changes in cardio physiology

A

CARDIAC OUTPUT
- increased 40 percent in pregnancy, almost half is increased by 8 weeks, maximal at mid pregnancy. It is because of augmented stroke volume that results from decreased vascular resistance
PULSE AND STROKE VOUME
- increase more later in pregnancy because of increased end-diastolic ventricular volume, results from pregnancy hypervolemia

Increase SV
Increase HR
Increase CO
increase preload 
decrease systemic vascular resistance
decrease afterload 

CO up 40%
HR up 17
vascular resistance- DECREASED

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2
Q

heart rate changes in pregnancy

A

HR rises in first trimester and slowly rises throughout pregnancy
by the middle of the third trimester, pulse is 15-20 beats above baseline
mild resting tachycardia is normal

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3
Q

systemic vascular resistance changes in pregnancy

A

fall in peripheral vascular resistance
decreased afterload
DROP in arterial BP (starting in 7th week)

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4
Q

normal cardiac exam findings in pregnant women

A
mammary souffle
jugular venous distension 
venous hum
S2P increased; S2 split 
S1M increased and widely split 
occasional s3
aortic or pulmonary flow murmurs
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5
Q

Symptoms heart disease in pregnancy

A
progressive dyspnea or orthopnea 
nocturnal cough 
hemoptysis
syncope 
chest pain
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6
Q

Clinical Findings heart disease pregnancy

A
cyanosis
clubbing of flingers
persistent neck vein distension 
systolic murmur grade 3/6 or greater 
diastolic murmur 
cardiomegaly 
persistant arrhythmia 
persistant split second sound 
criteria for pulmonary hypertension
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7
Q

Heart changes in pregnancy

A
diaphram elevation 
benign pericardial effusion 
exagerated splitting of first sound 
no changes in aortic/pulm elements in second sound 
loud, easily heard third sound 
systolic murmur
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8
Q

EKG changes

A

-Mean QRS can shift leftward due to elevation of the diaphragm
-Can return to the right as the fetus descends at pregnancy end
-Minor ST-segment and T-wave changes may be observed
–Less often, T-wave inversions may appear transiently in the left precordial leads.
- These changes are seldom of sufficient magnitude to raise the question of ischemic heart disease

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9
Q

normal echocardiography changes

A
  • Small, silent pericardial effusion = common
  • Slightly but significantly increased tricuspid regurgitation
  • Left atrial end-diastolic dimension
  • Left ventricular mass
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10
Q

effects of fetus

A

worsening heart function
decreased oxygenation to tissues (including placenta)
decreased oxygen to fetus
IUGR, NRFHT

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11
Q

Palpitations in Pregnancy

A

occur frequently during pregnancy
common indication for cardiac eval
look for arrhythmia with EKG
if abnormal EKG, do echo to look for structural heart disease as underlying cause

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12
Q

physical exam for heart disease

A

HR
weight gain
SPO2
How many flights of stairs can you walk up with ease? Two? One? None?
Can you walk a level block?
Can you sleep flat in bed? How many pillows do you use?
Does your heart race?
Do you have chest pain?
• Does this occur with exercise?
• Do you have pain when your heart races?

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13
Q

Mitral Valve Prolapse (williams)

A

left atrium and left ventricle
blood backed up from left atrium into lungs
mitral insufficiency
mostly asymptomatic
sometimes experience anxiety, palpitations, atypical chest pain, dyspnea with exertion, and syncope

rare complications in pregnancy
hypervolemia may improve alignment of the mitral valve

NOT considered an indication for infective endocarditis prophylaxis

symptomatic women receive beta blockers to decrease sympathetic tone, relieve chest pain and palpitations and reduce the risk of life-threatening arrhythmias

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14
Q

headache etiology in pregnancy

A

hormonal changes, increase in blood volume, tension, postural changes, muscle strain, preeclampsia (3rd trimester)

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15
Q

common headache triggers

A

inadequate sleep, smoke, change in caffeine, stress, hormones, eyestrain, sensory overload, very cold food/drinks, MSG, chocolate, tyramine containing foods, alcohol

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16
Q

Migrane patho

A

without aura: unilateral, throbbing, N/V, photophobia
with aura: hallucinations, acrotoma, aphasia, numbness/weakness, can happen without a headache, reversible in 5-60minutes
chronic: 15 days/month for greater than 3 months

often decrease in pregnancy (2nd and 3rd)
increase risk of preeclampsia

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17
Q

Migraine pharm

A
  • acetaminophen when symptoms start
  • acetinophen + metoclopramide (reglan) or compazine
  • aceta + codeine= watch for rebound headache with overuse NAS
  • aceta + caffeine
  • Fioricet = rebound headache with overuse
  • compazine (antiemetic)
  • triptans NOT first line
  • opioids AVOID can worsen
  • severe= IV hydration, IV antiemetics, IV mag, benadryl, compazine, botox
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18
Q

patient education migraine pharm

A
  • tylenol 4g max per day
  • NO NSAIDS, NO ergots
  • tylenol with caffeine (how much extra caffeine)
  • if they take fioricet- already HAS tylenol.. dont take more
  • tylenol given at early onset
  • NO ergots NO Ibuprofen
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19
Q

Tension headaches patho

A
- most in pregnancy 
infrequent episode
- less than 1/month
- last 30 minutes- 7 days
- bilateral, non-pulsing, not worse with activity 
frequent episode
- >10 per month
- both N/V
- photophobia or phonophobia 
Chronic
- >15 days
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20
Q

tension pharm

A

aceta.
aceta + caffeine
aceta + codeine
Fioricet

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21
Q

non-pharm cluster treatments

A

relaxation, breathing, meditation, visual/guided imagery, progressive relaxation, cognitive behavioral therapy, physical therpay (massage, TENS, chiropractic, heat/cold) biofeedback, regular and adequate sleep patterns, dietary modifications; some cheese, salty foods

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22
Q

cluster headaches

A

pre-existing= neurology

presentation: Unilateral, severe, explosive, 15 minutes to 3 hours, watery eyes, stuffy nose, sweating

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23
Q

cluster headache treatment

A

100% 02
sumatriptan
topical lidocaine inside nostril
preventative: verapamil, glucocorticoids

24
Q

postpartum headache

A

first week

differentials: preeclampsia, consider anesthesia complications, CVT, postpartum angiopathy

25
secondary headaches
idiopathic intracranial hypertension: loss of vision complication, no issue to pregnancy central venous thrombosis: subarachnoid hemorhage reversible cerebral vasoconstriction syndrome
26
risks associated with migraine headaches
severe migraines <8 weeks: at risk for fetal-limb reduciton defects, MI, CV disease, venous thromboembolism, preeclampsia, gHTN
27
SNOOP
S: Systemic symptoms: illness or condition (fever) N: neurological symptoms or abnormal signs (altered mental status, change in vision, seizures) O: Onset is new or sudden or severe (worst headache of my life, subarachnoid hemorrhage?_ O: other associated conditions or features (trauma, illicit drug use, awakens from sleep) P: previous HA history with changes in symptoms
28
lactogenesis II
"milk coming in" 32 to 96 hours after birth rapid drop in maternal progesterone levels following the expulsion of the placenta combines with the secretion of prolactin and other permissive hormones such as cortisol and insulin to trigger lactogenesis II
29
Breastfeeding I/O
at least 3 poops per day after day 4 | at least 6 wet/heavy diapers after day 4
30
breastfeeding triage
vomiting, lethargy, breathing problems, refusing to feed press the forehead skin- is it yellow underneath? how many times in 24 hours are you nursing? (less than 8 is bad) how many poopy diapers in 24 hours (less than 3 or 4 by day 4) are poops yellow by day 4? how many wet of heavy diapers? (less than 4 is bad) can you hear the baby swallowing? is there red staining in the diaper? (less than day 3 is normal) can you tell if milk is in?
31
feedback inhibitor of lactation
milk protein that inhibits milk secretion as milk accumulates in the alveoli. the longer milk remains in the breast, the higher concentrations of FIL, which downregulates milk production.
32
breastfeeding weight loss
``` 5-7% of weight in hospital or by day 4 regain birthweight by 2 weeks 4-7oz a week during first month 1-2 lb/week for 1-6 months 1lb/month from 6-1year ```
33
nutrition for lactation
no dietary restrictions can help with weight loss breastfed fine if mom only eats 1800 calories a day overweight women can restrict by 500 calories can have moderate excersize
34
medications in lactation
less than 1% is transferred, some degree of transfer present much less than in utero more in colostrum
35
colostrum components
Water makes up majority of human milk (87.5%) Colostrum is present from 12-16wks EGA onward Thicker, yellowish (d/t beta carotene) 2-20ml/feeding, about 100ml avail during first 24h after birth higher in protein and minerals, and fat soluble vitamins than mature milk ++ sodium, chloride, potassium, carotenoids Note that the breast cannot synthesize water soluble vitamins (these must come from the mother’s diet - must supplement B12 if vegan) lower in sugars, fat, and lactose than mature milk Mild laxative effect
36
immunologic properties of milk
secretory IgA interferon fibronectin pancreatic trypsin inhibitor
37
mastitis
risk factors: cracked or damaged nipples, plugged milk ducts, milk stasis by engorgement or ineffective milk removal, blocked nipple poore, nasal carrier of s. aureus, hyperlactation or high rate of milk synthesis, insulin dependent DM, nipple piercing
38
contraindications to TOLAC
more than 2 sections classical incision previous uterine rupture other contraindications to vaginal delivery twins are okay not great candidates: uncontrolled diabetes, recurring issues (cephalo-pelvic disportion, failure to progress,) higher rates of VBAcing if you go into spontaneous labor contraindicated medications: miso and any cervical ripening (cervidil) can use pitocin- increases risk of rupture 2-3 times need to have a physician in the hospital (whole staff for c/section)
39
why PTL??
activation of HPA axis prematurely pathologic uterine distention inflamation (increased prostaglandin) decidua issues (abruption, ect...
40
PTL triage
fetal fibronectin (greater than 20 weeks, marker of PTL, hormone released) when its negative it is pretty sure not PTL, but positive does not mean much ferm, pool, dye speculum until proven placental location transvaginal US for cervical length cervical change can only be deduced if cervix is more than 2cm and 80% effaced (people walk around at that)
41
stopping PTL
``` IV hydration mag sulfate bolus beta methazone terb (only for labor with tachysystole) niphedipine (calcium channel blockers NOT with mag) cerclage up to 24 weeks (put in 12-15) indomethicin (no more than 48) progesterone start 16-20 weeks (injeciton or vaginal) ```
42
shortened cervical length
less than 25mm 14-28 weeks
43
barker hypothesis
intrauterine environment is the first environment for a human. What happens there has an impact.
44
pregnancy/crisis
Jordan (p. 293): we could think of pregnancy as a crisis in that it is a “turning point or opportunity” that creates “disequilibrium” and prompts the pregnant person and the family to adapt to/make functional changes that are both physical and psychological. The successful, healthy adaptation to this “crisis” depends upon the pregnant person’s perspective on the crisis, the person’s access to resources, and the “resiliency” of both the person and the family
45
anxiety/depression pharm
more likely to have relapse if pt. already on meds and we take them off SSRI (c) Venlafaxine (c) SNRI zoloft most safe prozac least most concentraion buproprion (c) paxil (D) ! (cardiac defects) NO PAROXITINE no valproic acid! (no) yes TCA (first line) benzos.. maybe ok? metabolize all meds faster the farther along in pregnancy you are
46
pp depression treatment
SSRI, CBT, first line no antidepressants for biopolar folks full trial of meds is 12 weeks at good dose, start feeling at 4-6 weeks
47
ideal antidepressant in breastfeeding
Highly protein bound, short-half life, a low M/P ratio, poor bioavailability ( poor oral absorption)
48
postpartum/breastfeeding anti-depressant recommendations
``` SSRI low risk with others monitor infant sedation/weight gain no pump and dump no routine milk or infant levels ```
49
diagnosis of preterm labor
gestational age 20-37 weeks documented regular UCs >6/hour ROM cervical change, greater than 2cm and 80% effaced
50
term definitions
Late preterm: 34-36w Moderate preterm: 32-33w Very preterm: 28-31w Extremely preterm: <28 w
51
clinical pathways to PTL
premature activation of HPA axis pathological uterine distension inflammation (increase prostaglandins) increase decidual hemmorhage
52
steps for PTL triage
Fetal monitoring with Doppler and toco STERILE SPECULUM EXAM BEFORE DIGITAL EXAM Obtain fFN specimen with DACRON swab, THEN obtain cultures Lightly rotate swab across posterior fornix of the vagina for 10 seconds to absorb cervicovaginal secretions Transfer swab to buffer solution in transport tube and cap Specimen is stable at room temperature for 24 hours Obtain other cervicovaginal cultures and test for PROM as indicated Direct assessment of cervix for dilation Digital exam for effacement and dilation, if PROM has been ruled out Consider ENDOVAGINAL Cervical Length if available.
53
stopping PTL meds
* Betamimetics - Ritodrine, Terbutaline * MgSO4•NSAID’s - Indomethacin, Clinoril * Calcium Channel Blockers - Nifedipine * Atosiban
54
PTL Risks
``` POVERTY genetics weathering hypothesis prior PTB= highest predictor low weight, chronic stress, fertility treatment occupational physical activity peridontal disease BV UTI ```
55
Cervical insufficiency
singleton pregnnacy cervical length less than 25 prior PTB ** TVU gold standard for detection
56
Rubella
can be asymptomatic, but still contagious symptoms: lymphadatomphy and rash. Also: nasal congestion, conjunctivitis, fever, malaise, person to person, airborne serological testing PCR choronic villus PCR after 22 weeks to be performed CRS unlikely after 20 weeks infection (worst in 1st trimester) US characteristics: microcephaly, cardiac, early growth retardation Congenital rubella syndrome: HEARING LOSS, cataracts, glaucoma, retinitis, patent ductus arteriosis, cardiac lesions
57
Varicella
positive serology for IgM and IgG transmitted: respiratory droplets, close contacts, crosses placenta from infected mother to fetus, infection can ascend form lesions in birth canal