Exam 3 Flashcards

1
Q

What are proteins made of? what are they converted into?

A

Proteins are made of nitrgoen and since we cannot break it down, we convert it into urea

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2
Q

What is urea?

A

The substance we urinate out with the help of our kidneys. We excrete it in order to get rid of nitrogen.

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3
Q

What are normal concentrations of urea in our body?

A

15 mg/dl

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4
Q

What are normal concentrations of creatinine in our body?

A

1 mg/dl

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5
Q

What substances are excreted in our urine?

A

urea and creatinine

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6
Q

How is urea measured?

A

In our body, we can measure it through blood work, this is called our blood urea nitrogen.

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7
Q

What is normal urine production? What if its more?

A

1 ml/min anything above that rate is diuresis

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8
Q

What is the condition for urine production below 0.3 ml/min?

A

This is oliguria and its a sign of renal failure, it causes high bun and creatine levels

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9
Q

What is a kidney stone?

A

These can form when one is dehydrated and oliguria. When urine is static and not much moves through the ureters, it can cause calcium to form into stones. When they go down the ureter, it can be painful.

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10
Q

What i a kidney stone is not removed?

A

urine will aumulate and cause back track, the renal pelvis can enlarge and cause hydronephorsi

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11
Q

Why is blood flow to the kidneys high?

A

20% of total blood flow is sent here because we are constantly making urea and creatinine so our kidneys must filter those out.

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12
Q

What are the 7 main substances in our blood?

A

Red blood cells, plasma proteins, water, glucose, sodium, urea, and creatinine.

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13
Q

What susbtance are filtered? which are reabsorbed?

A

Water, glucose, sodium, urea, and creatinine are filtered out. Water, glucose, sodium are reabsorbed

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14
Q

What happens at the loop of henle?

A

sodium reabsorption

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15
Q

What does long loops of henle tell us about an animal?

A

that there is more water and sodium reabsorption

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16
Q

Blood enters the nephron at what rate?

A

1 l/min

17
Q

What is the glomerular filtration rate?

A

125 ml/min

18
Q

What is renal failure?

A

when our glomerular filtration rate goes below 30 ml/min

19
Q

What are the treatment plans for renal failure?

A

dialysis, transplant, or death

20
Q

What are the 2 types of hematuria?

A

GLomerular: red blood cells are filtered out in glomerulus and make their way through the nephron.
Non-Glomerular: anything past the glomerulus that causes red blood cells to be in the urine.

21
Q

How can we tell the difference between glomerular and non glomerular hematuria?

A

Red blood cells are biconcave discs. If the red blood cells came from glomerulus, their shape would be dysmorphic.

22
Q

Water isreabsorbed in two processess called

A

Mandatory water reabsorption and facilitated water reabosorption.

23
Q

where does mandatory water reabsoprtion occur?

A

pct

24
Q

Where does facilitated water reabsorption occur?

A

colleting duct

25
Q

What does facilitated water reabsorption rely on?

A

ADH

26
Q

What is ADH?

A

A hormone produced in the posterior pituitary and if adh is high, it prevents urinating. If ADH is low, there will be less facilitated water absorption and more urine.

27
Q

What must we do to absorb water?

A

Sodium has to be absorbed first and water will follow through osmosis.

28
Q

How is sodium reabsorbed?

A

Along the proximal convuluted tubule, in the apical membrane, there is sodium glucose transporters to take sodium in and then on the basal membrane, we have sodium, potassium atp ase to pump sodium out. After this happens, water can follow.