Exam 3 Ch. 6 Flashcards

(34 cards)

0
Q

Virus

A
  1. Infectious agent w/ simple acellular organization
  2. No metabolism
  3. Reproduce only w/in living host cell
  4. Size 10-400 nm
  5. Infect animals, plants, fungi, Archea, bacteria
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1
Q

Virology

A

Study of viruses & other acellular agents

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2
Q

Viruses have no ___

A

Metabolism

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3
Q

Nucleocapsid

A

Protein coat + nucleic acid

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4
Q

___ ____ encodes for protein coat

A

Nucleic acid

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5
Q

Capsid

A
  1. Protective protein coat
  2. Aids in transfer of Nucleic Acid b/w host cells
  3. Sub unit is capsomer which self assembles
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6
Q

Spikes

A

Proteins projecting from envelope often used for attachment or release from host cell, some are enzymes

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7
Q

Enveloped virus

A

Virus w/ a membrane surrounding nucleocapsid

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8
Q

Non-enveloped/ Naked Virus

A

No envelope!

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9
Q

Virion

A

Complete virus particle

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10
Q

Bacteriophage

A

Virus that infects bacteria

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11
Q

Plus/positive strand RNA

A

RNA genome identical to mRNA

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12
Q

Minus/ negative strand RNA/ DNA

A

Genome complementary to mRNA

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13
Q

Steps of Viral Multiplication

A
  1. Adsorption
  2. Entry into host cell
  3. Synthesis
  4. Assembly
  5. Release
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14
Q

Adsorption

A

Receptors on host cell bind to molecules on surface of vision

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15
Q

Entry into host cell

A

Fusion w/ host cell membrane or by endocytosis or injection of nucleic acid

16
Q

Synthesis

A

Production of virus parts by host cell

17
Q

____ ____ usually take over host cell

A

Early proteins

18
Q

____ ____ usually responsible for capsid protein production, self assembly & release

A

Late proteins

19
Q

Assembly

A

Put together vision particles either in nucleus or cytoplasm

20
Q

Release

A

Budding or lysis of host cell

21
Q

Virulent phage

A

Immediately takes over host cell followed by release from host cell by lysis

22
Q

Temperate phage

A

Can either immediately take over & Lyse host cell or can remain in host cell w/out destroying it

23
Q

Lytic

A

Take over host cell & lyse

24
Lysogenic
Phage DNA integrates into host cell chromosome & waits till induction occurs where phage DNA is triggered to come out by stress & then takes over host cell
25
Lysogeny
Process of bacterial cell being infected by temperate phage & copying the phage every generation
26
Archeal viruses can be either
Virulent or temperate
27
Cytocidal effect
Results in cell death, lysis
28
Cytopathic effects
Damage to host cell caused by viral replication/ synthesis/release like budding, viral inclusions, enlargement of cell, fusion of cells
29
Oncogenic viruses
Viruses that cause cancer often by inactivating tumor-suppressor genes normally in host cell
30
Plaques
Form when virus lyses host cells
31
Viroids
1. Naked circular ssRNA | 2. Use host cell DNA-dependent RNA polymerase to maked RNA copies
32
Virusoids
1. Satellite 2. Closed circular ssRNAs 3. Have genes
33
Prion
Proteinaceous infectious particle Misfolded protein Causes normal proteins to Misfold