EXAM 3- Cholinergic drugs Flashcards

1
Q

Ach is released:

A

nerve impulse passes

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2
Q

For nerve impulse to be transmitted from one nerve ending to another-

A

neurohormone is needed

  • Ach
  • AchE
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3
Q

Ach inactivated by

A

AchE

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4
Q

Ach

A

transmits nerve impulses across the parasympathetic branch of the autonomic nervous system

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5
Q

AChE

A

inactivates the neurotransmission of ACh

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6
Q

glaucoma

A

disorder of increased pressure within anterior chamber of eye

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7
Q

glaucoma prescribed with

A

-cholinergic drug: pilocarpine, which produces miosis (Constriction of iris), allowing for passage of fluid in chamber, thus reducing pressure

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8
Q

Myasthenia Gravis

A

rapid fatigue of skeletal muscles due to lack of Ach released at the nerve endings of parasympathetic nerve fibers

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9
Q

Myasthenia Gravis prescribed with

A

Pyridostigimine

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10
Q

treatment of urinary retention by relaxing bladder sphincter

A

Bethanechol

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11
Q

cholinergic drugs are not selective in action=

A

so many organs may experience the effect.

-N/D, abd cramping, salivation, muscle weakness, frequency.

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12
Q

Nursing process: glaucoma

A

-observe redness, inflammation drainage or eye
-assure med reads “for Opthalmic Use”
-When administering eye drops:
head back, eyes up, dropper shouldn’t touch pt; place drop in conjunctival sac

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13
Q

nursing process: urinary retention

A
  • assess for bladder distention
  • I&O
  • assist bed pan or provide call bell
  • observe for s&s of adverse reactions
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14
Q

cholinergic-blocking drugs

A

-block Ach in PNS

also called anti-cholinergic, parasympathomimetic blocking

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15
Q

cholinergic-blocking drugs: when PNS is inhibited-

A

Ach cannot access the receptors (nicotinic/muscarinic)

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16
Q

cholinergic-blocking drugs: heart

A

increase HR

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17
Q

cholinergic-blocking drugs: Respiratory tract

A

dry mucus membranes and cause bronchial dilation

18
Q

cholinergic-blocking drugs: GI tract

A

decrease GI motility, secretions, salivation

19
Q

cholinergic-blocking drugs: Urinary tract

A

decrease bladder contraction, resulting in urinary retention

20
Q

cholinergic-blocking drugs: eye

A

dilation, increase in intraocular pressure

21
Q

cholinergic-blocking drugs: ____ muscle rigidity and ____ tremors in ____ disease.

A

decreases, diminishes, Parkison’s.

22
Q

cholinergic-blocking drugs: used to inhibit the _____.

A

vagal stimulus

23
Q

cholinergic-blocking drugs: relaxation of smooth muscles in the bronchi

A
  • Decrease airway resistance
  • Bronchodilation
  • used for IBS
  • Neurogenic bladder and incontinence
  • Reduce gastric and pancreatic secretions (help with acute pancreatitis)
  • Used pre-op to reduce respiratory secretions
24
Q

adverse reactions of cholinergic-blocking drugs: Cardiovascular

A
  • big increase in HR

- dysrhythmias

25
Q

adverse reactions of cholinergic-blocking drugs: CNS

A
  • excitation
  • restlessness
  • irritability
  • disorientation
  • hallucinations
26
Q

adverse reactions of cholinergic-blocking drugs: Eye

A
  • dilates pupils a lot

- bigger increase in intraocular pressure

27
Q

adverse reactions of cholinergic-blocking drugs: GI

A
  • major decrease of salivation, gastric secretions, and motility
  • constipation
28
Q

adverse reactions of cholinergic-blocking drugs: GU

A

urinary retention

29
Q

adverse reactions of cholinergic-blocking drugs: respiratory

A
  • major decrease in respiratory secretions
30
Q

concerns with elderly on cholinergic blocking drugs:

A
  • confusion or excitement even with small doses
  • hallucinations, delirium
  • report unusual signs to physician asap
31
Q

special precautions of cholinergic-blocking in pt with: glaucoma

A

-because of mydriasis and increased ocular pressure

32
Q

special precautions of cholinergic-blocking in pt with enlarged prostate

A

since urinary retention may occur.

-caution includes OTC meds that may include atropine or other cholinergic drugs

33
Q

special precautions of cholinergic-blocking in pt with acute asthma or

A

other respiratory distress.

34
Q

nursing process for cholinergic-blocking:

A
  • History of present disorders
  • What is reason for administering drug?
  • V/S
  • Any dehydration noted?
35
Q

cholinergic-blocking: If given for patient with heart block-

A

Cardiac monitor – (change in rate, rhythm)

36
Q

cholinergic-blocking: if used as pre-op med-

A
  • Void before med is given
  • Usually given w 1 or 2 other meds as pre op med.
  • Inform patient that dry mouth is NORMAL and NOT to take fluids prior to surgery.
  • administer ON TIME so as to assure optimum effect of medication prior to admin of anesthesia
37
Q

cholinergic-blocking: for older patients-

A
  • Might not be given to patients over 60 due to effects on eye and CNS
  • Watch for heat prostration in summer since ability to sweat has been effected.
  • Watch for excitement/confusion.
  • Assist with ambulation if on med routinely
38
Q

education with prolonged use of cholinergic-blocking:

A

-Inform provider of adverse reactions

39
Q

education with prolonged use of cholinergic-blocking: photophobia

A

wear sunglasses, soft light

40
Q

education with prolonged use of cholinergic-blocking: Dry mouth

A

take frequent sips of water during the day; chew gum or dissolve hard candy

41
Q

education with prolonged use of cholinergic-blocking: constipation

A

drink plenty of fluids, increase fiber in diet

42
Q

education with prolonged use of cholinergic-blocking: heat prostration

A

use fans, sponge bath.