exam 3- porcine stress syndrome

Question 1

porcine stress syndrome aka ___

Answer 1

malignant hyperthermia

Question 2

PSS is a condition in pigs brought on by ___ or ___

Answer 2

stress(transportation)/exercise

Question 3

PSS results from an autosomal recessive gene that codes for ___ in the ___ of skeletal muscles

as a result, what happens?

Answer 3

the ryanodine receptor
SR

calcium release from SR is poorly controlled during stimulation of muscle to contract –> over-stimulation

Question 4

in some ways PSS is a malfunction of __

normally, when pig is under stress, sympathetic NS will fire (overstimulation of the ____ receptors), but in PSS, the response is not coordinated

Answer 4

the sympathetic mass discharge

Beta2 adrenergic receptors

Question 5

in PSS, the muscles spasm in uncontrolled fashion, ___ is broken down to ___, fueling skeletal muscle –> strong contractions - ATP used up quickly, this generates a lot of metabolic heat and ___, which tends to cook/break down the muscle, making it this color ___

Answer 5

glycogen
glucose

lactic acid
pink/slushy

Question 6

in PSS, ___ muscle is much more affected than ___ muscle

Answer 6

white muscle (glycolytic)
red muscle (slow phasic)

Question 7

in PSS, blood levels of ___ are up to 3 times normal

Answer 7

epinephrine

Question 8

the animals internal temp rises quickly and if it doesnt die frm hyperthermia, it goes into shock when ATP is used up and the internal temp drops quickly and the animal goes into ___

Answer 8

hypothermia