Exam 3 Practice Test Flashcards

1
Q

Parkinson’s

A young patient has just been diagnosed with mild Parkinson’s. What drug should the nurse expect as first line treatment?

A

A dopamine agonist like pramipexole (mirapex). Levodopa wears off in time, and younger patients can handle the SE.

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2
Q

The nurse is preparing to give a drug to reduce the wearing-off effect of levodopa. What is the drug, and when is the nurse preparing it?

A

Selegiline (Eldepryl) in the morning because of insomnia

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3
Q

A patient is on amantadine to reduce dyskinesias caused by levodopa. Which side effects should the nurse EXPECT?

  • urinary retention
  • orthostatic hypotension
  • livedo reticularis
  • CNS effects
  • gambling
A
  • urinary retention (anticholinergic)
  • livedo reticularis (mottled discoloration)
  • CNS effects
  • -
  • orthostatic hypotension is selegiline
  • gambling is pramipexole
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4
Q

A patient with Parkinson’s is complaining of dry mouth. Which two drugs might the nurse expect to see in their chart?

A
  • benztropine (Cogentin) is an anticholinergic

- amantadine is an antiviral

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5
Q

A patient with Parkinson’s was advised to avoid high-protein meals. What drug combination are they on?

A

Levodopa/Carbidopa – n/v is a huge side effect.

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6
Q

A patient with Parkinson’s is extremely agitated and is showing signs that they might become psychotic. Is the nurse surprised, and what do they avoid?

A

No – psychosis, anxiety, and agitation are known AE.

Avoid 1st gen antipsychotics like Haldol.

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7
Q

A nurse is preparing a patient’s first dose of donepezil for Alzheimer’s disease. They note that the patient is also on prozac. How does the nurse proceed?

A

Gives as planned; anticholinergics are the drug-drug for donepezil.

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8
Q

Which Alzheimer’s drug needs to be given late in the day?

A

donepezil (Aricept) due to bradycardia, fainting, falls

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9
Q

A caregiver for an Alzheimer’s patient asks for some Miralax to help their loved one poop. Which drug does the nurse expect to see in the patient’s chart?

A

memantine

donepezil is a cholinesterase inhibitor so has opposite of anticholinergic SE –> diarrhea

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10
Q

After starting a patient on memantine, they seem much more disoriented and complain of a headache. Is that expected or unexpected?

A

Expected – too much calcium has entered the neurons

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11
Q

A patient’s caregiver says they haven’t seen any improvement over the three days the patient has been on donepezil. Is that expected or unexpected?

A

Expected: low and slow, and a looooong (70 hour) half life

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12
Q

A patient reports sleep driving on zolpidem (Ambien). Which benzodiazepine would also be a sleep aid?

A

triazolam (Halcion)

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13
Q

A patient has a substance use history and insomnia. Which drug might be a good choice for a sleep aid?

A

zolpidem or hydroxyzine

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14
Q

A patient states that they skip their buspirone when they’re having a few glasses of wine since they only need it when they’re anxious. Does the nurse intervene?

A

Yes. It’s not for PRN use, and it doesn’t have an ETOH interaction.

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15
Q

A patient who has been given IV midazolam has a BP of 80/40. What does the nurse expect?

A

flumazenil admin over 15 seconds, repeat every minute

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16
Q

A patient with suicidal ideation states that their anxiety has gotten really bad. Can they have a benzo?

A

Nope, try buspirone for daily or hydroxyzine for PRN

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17
Q

A patient’s EKG shows a prolonged QT interval. Which anxiolytic does the nurse expect in the patient’s medication list?

A

long-term hydroxyzine

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18
Q

A patient with PTSD wants an anxiolytic. What does the nurse expect?

A

An SSRI – it’s the only thing proven to help.

19
Q

A patient reports dry mouth with hydroxyzine and sips on grapefruit juice throughout the day. Is that okay?

A

Yep – dry mouth is expected, and it’s Buspar that has the grapefruit interaction.

20
Q

A patient on phenytoin reports a rash. Okay?

A

NOPE – SJS/toxic epidermal necrolysis

21
Q

Which AED should a patient tell their dentist about?

A

phenytoin

22
Q

A patient receiving IV AED reports that their groin is itching. Which drug are they on?

A

fosphenytoin

23
Q

A patient on carbamezepine comes in with an infection. What are the concerns?

A
  • BM suppression

- drug interactions with lots of anti-infectives

24
Q

A patient on valproic acid complains of nausea, anorexia, and abdominal pain. Which side effect is most worrying?

A

Hepatotoxicity/pancreatitis

25
Q

A patient says: “I’ve had this weird eye thing since being on Gabapentin – is that a micro-seizure?”

A

Nope, it’s nystagmus

26
Q

Should a nurse question benztropine for Parkinson’s for a patient with glaucoma?

A

Yep, it’s an anticholinergic

27
Q

Which RA treatment plan might a patient choose during a pandemic?

A

NSAIDs and Glucocorticoids – avoid immunosuppression

28
Q

A patient states: “Running is my life. I don’t want to give it up with RA.” Which drug categories might be a fit?

A

DMARDs reduce joint destruction

29
Q

A patient on methotrexate wants to become pregnant. What should their RA drug plan be in this process?

A

Any of the other drugs

30
Q

A patient is getting started on methotrexate. What should they do while they’re waiting for it to work?

A

treat with NSAID and take folic acid

31
Q

A patient with a significant family history of cancer needs to start antirheumatic therapy. Which drugs might increase their risk of cancer?

A

DMARDs – methotrexate and etanercept

32
Q

When should a patient with RA be tested for TB

A

before biologic DMARD (etanercept)

33
Q

A patient with tophi started allopurinol and says, can’t you just switch me back to cholchicine? Why, and why can’t you?

A

Cholchicine is great for acute but doesn’t actually help reduce tophi.

34
Q

A patient on allopurinol reports stomach upset. How should the nurse proceed?

A

Give as usual. It’s colchicine that’s the n/v problem.

35
Q

A patient on colchicine reports that they’ve increased their fluid intake using grapefruit juice. What’s wrong?

A

Grapefruit juice, and flushing is more important for allopurinol.

36
Q

A patient on colchicine states: “It’s really helped my feet, but now my legs have been hurting. Is that part of gout too?”

A

Nope, look for rhabdo

37
Q

In their first day of colchicine treatment, a patient states: “It feels like the colchicine you gave me a couple hours ago wore off. Can I have another dose?”

A

Nope, 1.2 mg loading, then 0.6 mg 1 hour later. Max 1.8/24 hours

38
Q

A patient states: “I take my calcium carbonate in divided doses with my breakfast and dinner” What’s wrong

A

food interactions – whole grain cereals, spinach, rhubarb, swiss chard, beets, bran

39
Q

A patient on alendronate says: “I sometimes wake up in the middle of the night and remember that I forgot my Fosamax. So I take it immediately on an empty stomach and go back to bed.” What’s wrong?

A

Esophagitis – remain upright for 30 minutes and take with a full glass of water.

40
Q

Which osteoporosis drug helps with bone mets, and which can increase risk?

A
  • alendronate helps

- teriparatide hurts

41
Q

A patient on denosumab states: “I always take my vitamin D and calcium, and I schedule dentist appointments for after I’ve gotten my Prolia injection.” What’s wrong?

A

Osteonecrosis of the jaw

42
Q

Which drug might be prescribed to a patient with severe osteoporosis?

A

teriparatide (Forteo) – rebuilds bones

43
Q

A patient states “I’ll be off of my MAOI for a week before starting my antidiabetic drugs” correct?

A

Nope, 14 days – hypoglycemia