Exam 3 Review Flashcards
(40 cards)
when the endothelium is damaged, the subendothelium is exposed. what molecule on the subendothelium is the first one bound by platelets?
von Willebrand factor
how would platelet clumps affect a CBC?
they would artificially lower the platelet count, making a clinically normal patient look thrombocytopenic
an incompatible major crossmatch predicts what?
acute hemolytic reactions
crossmatching detects
sensitization: detects ab that might cause an immediate reaction
blood typing avoids
sensitization: best to avoid a delay transfusion reaction: can predict what will happen
what are the most important dog EAs?
DEA 1.1, 1.2
a dog can be transfused safely one time without a cross-match
what are the blood types of cats?
A, B, AB
what blood type of cats have very strong hemagglutinating antibodies
type B cats have very strong hemagglutinating anti-A antibodies
cross-matching
detects presence of antibodies in recipient serum that may react with donor RBC to cause an immediate transfusion rxn
major cross match
donor cells + recipient serum
among dogs, cats, and horses, major crossmatching is most important in which species for a first-time transfusion?
cats
you see a cat that has a known monoclonal immunoglobulin in the serum and neoplastic plasma cells in the spleen. you wish to evaluate for bence-jones proteins. what sample and test is going to be most useful?
urine protein electrophoresis with immunofixation
minor crossmatch
donor plasma and recipient RBC- detects abs in donor plasma
much less important
a dog is transfused for the first time with packed cells from a “universal donor”. you did not blood type him first. His PCV raises slightly, then drops almost to the pre-transfusion value over the next 5-10 days, with no signs of bleeding. what condition is he experiencing?
a delayed transfusion reaction
a 12-year-old dog has a PCV of 18% (32-47%), normal protein, and history of CHF. the best product for transfusion is
packed cells: need to replace oxygen-carrying capacity
what is a good indicator of inflammation in ruminants and horses?
increased fibrinogen
what are causes of hyperbilirubinemia (icterus)?
- pre-hepatic: hyperbilirubinemia: things bursting RBC
- hepatic: lepto, sepsis
- post-hepatic: anorexia: anything after conjugated bilirubin gets stopped
matching patient serum with donor erythrocytes describes the procedure for which test?
major crossmatch
the best explanation for increased GGT in a calf is
ingestion of colostrum
fasting hyperbilirubinemia is particularly prominent in what species?
horses
you see a blood panel on a 9 year old dog. the only abnormality is increased albumin. what is the most likely interpretation for this protein change?
dehydration
what analyte abnormality CANNOT be explained by a course of gluococorticoids?
bilirubin
what bloodwork values can increase with muscle damage?
- CK: very sensitive: acutely risees
- AST: later (1-3 days)
- ALT
