exam 4 Flashcards

(49 cards)

1
Q

what is transcription?

A

synthesis of RNA using info in DNA

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2
Q

what is translation?

A

synthesis of polypeptide using info in mRNA

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3
Q

where does translation take place

A

ribosomes

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4
Q

what does genetic info flow from

A

dna to rna to protein

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5
Q

in which cell type do translation and transcription happen simultaneously?

A

prokaryotes

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6
Q

how are the words of a gene transcribed in a codon?

A

three nucleotide words of mRNA

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7
Q

what is the initiation codon?

A

AUG

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8
Q

what are the stop codons

A

UAA, UGA, UAG

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9
Q

true/false: more than one codon can specify a particular amino acid

A

true

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10
Q

the genetic code is nearly _____

A

universal

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11
Q

how is mRNA read?

A

5’ to 3’ end

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12
Q

how is the template strand read?

A

3’ to 5’

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13
Q

what signals the transcription start point?

A

promoters

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14
Q

what do transcription factors bind to

A

TATA box promoter

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15
Q

what is added during RNA processing?

A

5’ cap and 3’ tail

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16
Q

what is spliced during RNA processing

A

introns

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17
Q

what does translation require

A

mRNA, tRNA, ribosomes, and translation factors

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18
Q

tRNA anticodons base-pairs are complementary to

A

codons on mRNA

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19
Q

which site holds incoming tRNA and the next amino acid for the chain?

A

A site

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20
Q

which site holds tRNA carrying growing polypeptide chain

21
Q

which site is the exit site?

22
Q

which direction does translation proceed along the mRNA?

23
Q

to which site does elongation continue to?

24
Q

to serve as genetic material, a molecule must be able to what

A

replicate faithfully, contain complex info, encode phenotype, and have capacity to vary

25
what is the inducible operon?
lac operon
26
what is the repressible operon
trp operon
27
the repressible operon ensures that transcription is
normally on but needs to be off
28
the inducible operon ensures that transcription is
normally off needs to be on
29
what bacteria does natural selection favor?
bacteria expressing only genes needed by cell
30
what happens in feedback inhibition?
the end product of metabolic product shuts down further synthesis by inhibiting enzyme activity
31
how do cells adjust production level of certain enzymes
gene expression regulation
32
what is an operon
entire stretch of DNA including operator, promoter, and genes controlled
33
where do genes in bacteria tend to be organized
clusters on bacterial chromosome, with transcription usually under control of single regulatory region
34
when is a trp operon repressor in active state
in the presence of corepressor tryptophan
35
what does a trp operon bind to
tryptophan
36
if tryptophan levels are high, what happens to the trp operon?
gets turned off
37
where do repressible enzymes usually function in, and what is the synthesis usually repressed by?
anabolic pathways; high levels of end product
38
where do inducible enzymes usually function in, and what is synthesis usually repressed by?
catabolic; chemical signal
39
what does the dense packing of heterochromatin do to the cell?
make it difficult to express encoded genetic info
40
what does the addition of methyl groups do?
condense chromatin and reduce transcription
41
what are non-adaptive evolutionary mechanisms?
mutations, gene flow, and genetic drift
42
what is an adaptive evolutionary mechanism?
natural selection
43
what is fitness defined by?
individual's contribution to future gens
44
what is a common ancestor
species/individual no longer alive that gave rise to multiple current species
45
can natural selection give rise to new traits?
no; can only increase or decrease heritable traits that are variable already in population
46
natural selection acts on what?
individuals
47
can individuals evolve?
no; only populations
48
what is a phenotype
the observable physical and physiological traits of organism determined by genetics
49