Exam 4 Flashcards
(65 cards)
what is chronological age
age since birth
what is biologic age
functional status
BP in elderly
increase in afterload –> leads to ventricular hypertrophy
Diastolic dysfunction
Catecholamine changes in elderly
increase in circulating catecholamines with decreased end organ responsiveness
Leads to reduced capacity to increase HR in response to hypotension, hypovolemia, hypoxia
Onset of IV drugs in elderly
delayed
elderly effects on breathing
decrease in chest wall compliance
loss of elastic recoil of lungs
increase in lung compliance
What lung volumes are decreased in elderly
Vital capacity
inspiratory reserve
Expiratory reserve
what lung volumes are increased in elderly
residual volume
functional residual capacity
in elderly is total lung capacity changed
NO
due to increase in residual volume and decrease in vital capacity
how is regulation of breathing affected with aging
decreased response to hypoxemia and hypercarbia
elderly response to CNS depressants
exaggerated response
postop delirium vs cognitive dysfunction
delirium appears soon after surgery
cognitive dysfunction appears weeks to months after
CV changes for obesity
increase in CO .1L/min per kg of fat
increase in O2 consumption
increase in CO2 production
LV hypertrophy
EKG changes for obesity
low voltage EKG
QT prolongation
Ischemia
Dysrhythmias
what is Pickwickian Syndrome
obesity hypoventilation syndrome - long term consequence of respiratory center in medulla failing to respond to hypercarbia
how is Pickwickian syndrome defined
BMI >30
Daytime PCO2>45
sleep disordered breathing in absence of other causes of hypoventilation
in obese patients how is volume of distribution altered
increased blood volume
increased CO
altered plasma binding
lipid solubility is altered
how are lipophilic drugs dosed
dosed on LBW (IBW x 1.3)
Loading and Maintenance dose type for Prop
Loading: LBW
Maintenance: TBW
Loading and Maintenance dose type for Roc
Loading: LBW
Maintenance: LBW
Loading and Maintenance dose type for Fentanyl
Loading: TBW
Maintenance: LBW
Loading dose type for Succs
Loading: TBW
what is Ma Huang
natural source of ephedrine
what is phentermine
norepi reuptake inhibitor