Exam 4 Flashcards
Actions of Anabolic Steroids
- Acts just like testosterone
- Binds to receptors inside of cells specifically muscle and when it binds to the receptor inside the cell it causes the production of new proteins and causes an increase in muscle mass
- Primary use of synthetic testosterone is to increase muscle mass
- > Resistance training athletes are the most likely to use these
- Anabolic steroids are a synthetic form of testosterone
- > If we take a synthetic form, the body stops producing the natural form since levels are kept high
- > In this case, the use of these has emasculating effects
- > Big muscle mass, but less manly in other aspects
Nutrition Practices for Competition
- Dietary manipulation during the competition phase will work if there were changes in the dietary practice during the training phase
- Ensure adequate fuel supplies during the event
- No matter the duration, the diet has to be able to cover it
- Different diets will cover different durations - Facilitate temperature regulation by preventing dehydration
- Has to have a lot of fluid in your dietary intake because lots of fluid is lost during events - Achieve desired weight classification while maintaining fuel and water supplies
- Some events have desired weight classifications
- If you are cutting weight to make weight, your diet needs to provide enough fuel and water so that if you do make weight you can still compete - Avoid gastrointestinal discomfort during competition
- You can not perform well when you are dealing with GI issues, so do not intake a diet that will cause discomfort
Risks Of Anabolic Steroids Use list
- Prolonged high dosages can lead to reductions in testosterone production
- Can cause an increase in estradiol concentrations
- Connective Tissue Damage
- High levels of synthetic testosterone causes prostate hypertrophy
- Ventricular hypertrophy in the heart
- Can effect thyroid function regulation
- High and continued use of synthetic testosterone can cause abnormal liver functions
- Uses of anabolic steroids cause a reduction in HDL and increase in LDL
- > cholesterol levels - Effects Women
- Effects Young aged boys
Factors Controlling the Resynthesis of Glycogen
- The Severity of Depletion
- The Extent of Muscle Trauma
- Amount of Dietary Carbohydrates
- With the optimal amount of carbohydrates in the diet, resynthesis is faster - Exercise Types Effect on Resynthesis of Glycogen
- Blood Lactate Concentrations
Should I combine Coffee and Creatine to increase ergogenic effects?
- Adding all three illegal substances together coffee, caffeine and creatine is a bad idea
- Caffeine negates the effects of creatine
- If you want your creatine to work, you need to refrain from drinking coffee
- > Start this before you start creatine loading, should probably stop drinking coffee a week before
- Caffeine is great for endurance athletes
- creatine is great for resistance training athletes
- > Benefit different pathways
Benefits of Pyruvate
- Increase in pyruvate increases glucose transport in active muscle
- Increases the uptake of glucose into the cell from the blood which conserves glycogen
- > If we can take glucose out of the blood to break it down for energy, we do not have to use the stored glycogen in the cell for energy
- Has effects that augment endurance athletes - Helps Aid Body Fat Loss
- Increases body fat loss when accompanied by low-calorie diet
- Potential Diet aid
Role of Magnesium
- Is involved most importantly with oxygen uptake and therefore energy production
- Exercise has detrimental effects on our levels of magnesium
- > Strenuous exercise increases our need for magnesium and it does that by causing us to lose it in sweat or urine
- The more magnesium we are losing the less energy we can produce
Eating During Exercise
- Exercise causes a suppression of insulin and increases stress hormones
- > Both are linked to extracting nutrients and keeping things like glucose levels where they need to be
- Ingestion of carbs during extended exercise is good since it will promote insulin production and make glucose available to cells
- Eating while exercising is good
- > Recommended rate of carbohydrate intake during exercise is 30-90g of carbohydrates total per hour
- > Even after 40 minute exercise sessions we can eat carbs as soon as we are done
- > Even if it is low intensity we want to bring in carbs, just do it at a lower level
- > Other variables matter such as size, weight, BMR, etc
- Liquid sources of carbohydrates are just as effective of solid carb sources
- > Exercise induces fluid loss, so liquid sources are much less problematic
- > Liquid help replenish the fluids we are losing
- > Want 6-8% fluid volume carbohydrate
- Optimal carbs to consume while exercising are liquids that have 6-8% of their volume as carbohydrates
Balanced Diet for Active Individuals
- If the composition of the diet remains the same as the number of calories increase, that diet is still acceptable
- If you are increasing your activity and change the diets components, it will change your diet for the better
- > Not dramatic shifts, but enough shifts that it will cause benefits
1. Increase a lot of carbohydrates - all ages are 58-68% carbs
2. Increase proteins - adult 19+ years old is 10-35% protein
3. Decrease fats - all ages are 20-35% fat
4. Vitamins and Minerals stay at the RDA
5. Increase fluids - Consume 2-3 hours before exercise, consume again 30 minutes before, during and 30 minutes after
Amino Acid Supplementation for Ergogenic Effect
- Athletes that do this are doing so because there is a general belief that you can boost the natural production of things like testosterone, insulin, or muscle strength by increasing the availability of amino acids
- Mostly for resistance athletes
- If you increase the availability of amino acids by supplementing the diet, you can cause a shift to continue to produce proteins
- Research does not back this ideology up
- ANY increase above the normal dietary levels of AAs, shows absolutely no gain
- One exception
- > If the dietary levels of protein was insufficient, then the AA supplementation brought the individual up to their normal level, therefore showing an increase up to normal levels
Role of Zinc
- Used for the repair of muscle tissue and energy production
- Exercise is a form of stress and stress depresses immune function and zinc negates that depression
- Zinc promotes bacterial replication and retards viral replication
-> To prevent or recover from the flu increase the amount of zinc in your diet
-> If you have a bacterial infection and you increase the amount of zinc you are getting, you will help the bacteria replicate and it is harder to get over that infection - There is an easy test to determine if you are dealing with a bacteria or viruses
-> A white blood cell count
Bacterial infections increase white blood cell amounts
-> Viral infections decrease white blood cell amounts - Exercise benefits by having zinc supplementation
-> Low doses of zinc, no more than 30 mg at a time are better than high doses
-> 30 mg of zinc 5x a day is positive, but 100 mg of zinc once a day is negative - Side effect of zinc whether it is dietary or supplementation is that it makes your food taste weird
Why should we add more carbs for more active individuals?
- Glycogen is more important as a fuel as exercise intensity increases
- There is a training adaptation to be able to store more glycogen
- > To store more glycogen, we need more glycogen in our body
- Make more glycogen by having excess carbohydrates that are converted into storage - Even if we store more glycogen, the glycogen reserves get exhausted within 2 hours of heavy endurance exercise
- Muscle glycogen is depleted within 30 minutes of near-maximal or submaximal effort
- > If we deplete the muscle glycogen, the rest of the glycogen is coming from the liver - The body can only store limited amount of carbohydrate
- Training adaptation is to allow us to store more carbs - Fat metabolism is linked to carb metabolism
- > By having more carbs, we can get better use of fats
- > Training adaptation is to switch energy sources from carbs to fats
Buffering Solutions Ergogenic Effects
- We know that when we are engaged in maximum exertion of resistance type training we are going to produce lactate
- > Accumulates in active cells
- Changes the pH of the cell by lowering it
- Changes the ability to do energy transfer by shutting off anaerobic pathways which are the gateways to aerobic pathways
- > Can not produce more energy
- Entire concept for buffering solutions is to increase the bicarbonate reserves, a natural blood buffer, which will allow us to deal with extra lactate and reduce the fatigue effect
- > Thus, giving us more energy
- Increasing sodium bicarbonate intake can negate effects to help this
- > It is baking soda
- In endurance athletes, we see a greater effect from the ingestion of sodium bicarbonate
- Dosage is IMPORTANT
- > Must be greater than or equal to 0.3 g per kg of body weight
- > Dosage exhausts itself in 6-8 minutes because the kidney’s job is to maintain the correct blood chemistry
- The cumulative anaerobic nature of the exercise is important as well
- > If we have a pathway completely dependent on an anaerobic component, bicarbonate can not keep up with lactate production regardless
Anabolic Steroid Techniques
- Most people combine techniques
1. Stacking - They do not use one source, they use several sources
- Use of multiple different steroid preparations
2. Pyramiding - Progressive increase in dosage
- Generally follows cycles
- Normal cycle is somewhere between 6-12 weeks
- > Over the course of these, the amount of steroid ingestion will increase
- Dosages can get as high as 40x the recommended medical dosage
- Once peak is reached, the usage tapers off so that there are a couple of months between their maximal dosage and the day of competition
- > This is done so it cannot be detected on competition day
Anti-cortisol Compounds: Glutamine
- A Nonessential amino acid
- Most abundant in blood plasma, skeletal muscle
- Represents more than 50% of the muscles free-pool of amino acids
- > present to maintain protein production
- Used to counteract the effects of cortisol that reduces our body taking it up in the first place
- Research says there is no gain to resistance athletes when they take glutamine powder
- Does not reduce the effect of exercise on the breakdown of catabolic proteins
- Another Possible mechanism
- > Glutamine is used as a fuel source to produce energy when our cells are fighting an infection
- > Macrophages and Lymphocytes are blood cells that fight infection by using glutamine for energy
- Research shows that glutamine supplements helps when fighting an infection and helps to train through illness, otherwise has no effect
Exceptions in the Effects of the Use of Anabolic Steroids
- Athletes are unable to get the same type of compounds or dosage
- > There is no controlled experimentation
- > There is no consistency across research
- > The lab has defined parameters, meaning they may not be testing what’s being used at the gym
- Research does show that steroids will cause an increase in mass muscle
- > May be due to protein or may be due to an increase in strength
- > We will look bigger
Mechanisms of Ergogenic Action
- They all do not do all of these things, but they have the potential to do some of these things
1. Act as a nervous system stimulant - Amphetamines, Catecholamines, and Caffeine
2. Increase storage and availability of limiting substance - Creatine, carbohydrates and chromium
- Increases the availability of something that can be limiting
3. Act as some sort of supplemental fuel source - Example is a concentrated glucose solution that is consumed or injected to increase blood glucose levels
4. Reduce or neutralize performance-inhibiting metabolic byproducts - Increasing amount of buffer there to prevent pH change which delays fatigues
- Sodium bicarbonate is an example
- > If we increase the amount of buffer to delay the onset of lactic acid it would decrease fatigue
- Sodium citrate
- > Make citric acid available to power the Kreb cycle
- Makes it so you don’t have to go through the breakdown of glucose to produce citric acid which leads to fatigue
5. Anything that facilitates recovery in an unnatural way is an ergogenic - Gatorade is one, but it is not banned
- higher levels of recovery aids are banned
6. Enhance the resistance-training responsiveness - Anabolic steroids
- > Synthetic testosterone, it is man made
- > Muscle mass increases
- > Growth hormone
3 Marketed Carbohydrate Sources
- Sports Drinks
- Sports Bars
- Sports Gels
- concentrated sports drinks
- since they are concentrated drink 4-8 ounces of water for every ounce of sports gel
How are ergogenics detected?
- Primary method for the detection of banned ergogenic substances is through a urine test
- Other methods include blood, saliva, etc
- NCAA has random drug testing
Role of Iron
- Red Blood Cells are recycled in the liver and the liver takes the iron and stores it
- > Storage forms and free forms
- Because we can recycle it and can make new hemoglobin when we make new RBC, it is a trace mineral but we still have to have it
- Hemoglobin and myoglobin both contain iron
- It is also present in some of the enzymes that function in energy production
- Important trace mineral for women during the menstrual phase of the menstrual cycle
- > Losing blood and blood loss increases anemia, so increasing iron can offset that
Differences in Nutrition For Training vs Competition
- Most of our time is spent training, so our daily nutritional practices are more related to training than they are to competition days
- No amount of dietary manipulation just before competition will make up for an otherwise everyday poor diet
When should you consume carbs after a workout to aid glycogen resynthesis?
- If you consume carbs immediately after exercise you are going to get higher resynthesis of glycogen within 4 hours of exercise
- If you delay consuming carbs after exercise for even 2 hours, then you will delay your glycogen resynthesis
- If the interval between exercise sessions is going to be short like less than 8 hours (2 workouts in a day), then carb ingestion should begin as soon as possible after the workout
- > 15-30 minutes post workout
- > Continue to load every 15-60 minutes until you can consume a larger meal
Red blood cell re-infusion, or blood doping technique
- non-pharmacological approach that is controlled, or banned
- Athlete is going to have 1-4 units of their blood drawn taken at an interval of every 3-8 weeks
- Blood plasma is 55% of the blood and is re-infused back into the athlete immediately
- The red blood cells are 45% of the total blood volume and are frozen and stored
- 1 to 7 days before an endurance event, the pact cells are re-infused
- > This increases the red blood cell volume, thus increasing hemoglobin between 8-20%
The order that the body looks for energy sources for replenishment
- Body looks for carbohydrates for energy first, then goes to proteins and last will go to fats