Exam 4 Flashcards
3 Types of Muscular Tissue
- Skeletal (voluntary and striated)
- Cardiac (involuntary and striated)
- Smooth (involuntary, non striated)
Functions of the Muscle
Producing body movements Stabilizing body position Regulating organ volume Moving substances throughout body Producing heat
Skeletal Muscle
Voluntary and Striated (striped with actin and myosin)
Tendon- Fibrous connective tissue binding muscle to bone
Ligament- Fibrous connective tissue binding bone to bone
Anatomy of Muscle Cell
Sarcolemma- Muscle cell membrane
Actin Filaments- Thin protein filaments
Myosin Filaments- Thick protein filaments
Mitochondria- Production of energy for contraction (ATP)
Sarcoplasmic Reticulum- Releases Ca+ into sarcoplasm (store calcium, cytoplasm of muscle cell)
Transverse Tubules- Extend in from the sarcolemma (transport Ca+ to Sarcoplasmic reticulum)
Neurotransmitter Junction- Site where motor nerve end plate connects to muscle fibers
Physiology of Muscle Contraction and Relaxation
- Synaptic vesicles release acetylcholine
- Acetylcholine binds with sarcolemma
- Acetylcholine travels through t-tubules to the interior of the cell
- Acetylcholine reaches sarcoplasmic reticulum and causes the release of stored Ca+ into sarcoplasm
- Ca+, ATP, O2 from myoglobin cause the muscle to contract
- Ca+ is pumped back into the sarcoplasmic reticulum causing muscle to relax (requires ATP) (secondary active transport –> swapping of Ca+ and Na+)
Cardiac Muscle
Involuntary and striated
Intercalated disk = allows cardiac muscle fibers to contract in coordinated fashion
Heart has its own internal pulse conduction system
Smooth Muscle
Involuntary and non-striated
Visceral smooth muscle –> large sheets of cells (found in walls of internal organs)
Multi unit smooth muscle –> Discrete group of cells (found in walls of small blood vessels, air passages)
3 General Functions of Nervous Tissue
- Sensory
- Motor
- Integrative
Nervous Tissue: Sensory
Senses change in external and internal environment
Called afferent nerves
Travels towards brain
Nervous Tissue: Motor
Allows for a response to happen
Called efferent nerves
Travels away from the brain
Nervous Tissue: Integrative
Decides if there needs to be a response, if yes –> triggers motor nerves
Called Interneurons
4 Parts of a Neuron
Dendrites (receive sensory info)
Nerve cell body (contains nucleus, mitochondria, ER)
Axon (surrounded by myelin sheath, provides insulation)
End plate (axon terminal, vesicles)
*Spaces in myelin sheath = nodes of ranvier
Depolarization
- Carries the electrical impulse down the axon
- Creates an action potential (changes cell membrane polarity)
- Releases neurotransmitter into the synapse
2 Types of Neurotransmitters
- Excitatory –> causes a response
Catecholamines (epinephrine, norepinephrine, dopamine)
Skeletal muscle - Inhibitory
Gamma Amino-Butyric Acid
Cardiac muscle
Process of Depolarization
- 3 Na+ leak into cell, 2 K+ leak out of cell
- Changes the resting membrane potential
- This polarity charge travels down the axon to the end plate –> release of a neurotransmitter into the synapse
- As charge travels down axon, the membrane must re-polarize to be allowed to depolarize at another time