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Flashcards in exam 6 Deck (17)
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1

hodgkins lymphomas have

reed sternberg cells, which makes it much more serious

2

lymphoma is

an idiopathic malignancy of the lymph system
viruses, carcinogens, smoking, genetics, immunocompromised (AIDs/transplants)

3

Hodgkins is

more treatable with radiation and chemo
alopecia

4

patients with lymphoma will take

immunosuppressants to kill of the WBC and give your body a "fresh start"

5

normal amount of blast cells in the bone marrow

1-2%

6

amount of blast cells of someone with leukemia

20% or higher
the blasts will "crowd out" of the bone marrow
high or low or normal wbc

7

myeloid stem cells

Positive myelopyroxidase

8

lymphoblastic stem cells

Positive TdT
B or T cells

9

what type of alterations to the CBC occur in leukemia

Panocytopenia

10

clinical manifestations of acute myeloid leukemia

Develops without warning
Symptoms develop over a few weeks
Fever and infection from neutropenia
Weakness, fatigue, dyspnea on exertion an pallor from anemia
Petechiae, ecchymosis and bleeding from thrombocytopenia
The proliferation of leukemic cells within organs leads to additional symptoms of pain from enlarged liver or spleen, hyperplasia of the gums and bone pain** from expansion of marrow
Petechiae are common

11

medical management of Aml

Neupogen
PRBC
Platlets
Chemotherapy- given in large dosages this helps prevent a relapse

12

what is chronic myeloid leukemia?

the same as acute over a long period of time
presence of chromosome 22 or philideaphea chromosome
life expectancy 5+ years
in men 30-50

13

clinical manifestations of Chronic myeloid leukemia

leukocyte count can exceed 100,00
leukocyte statis in lungs of other parts of the body, can cause shortness of breath

14

Acute lymphocytic leukemia

common in young boys peak age is 4yo
after 50 chances increase

15

clinical manifestations of ALL

panocytopenia
high or low WBC but they are immature
enlarged liver or spleen and bone pain
CNS is a frequent site for leukemic cells, nerve palsies and head ache s
patients may experience nerve palsies or H/A and vomiting because of menigeal involvement
pain in breasts and testies

16

main difference between ALL and AML**

CNS invasion

17

dexamethasone is given to leukemia patients because

it is toxic to lymphoid cells