Exam 8 - Monitoring CO & Blood Flow Flashcards
(32 cards)
CO needed to calculate:
- Stroke Volume
- Blood O2 transport
- Intrapulmonary shunting
- SVR
Normal CO
4-8 L/min
What can change CO
- Decrease in contractility
- MI / Drugs / Acidosis / Hypoxia - Decrease in preload
- Changes in SVR
- Increase: arteriosclerosis / hypertension
- Decrease: septic shock - Decreased ventricular flow (valve disease)
CO calculation
CO = SV x HR
Normal SV
60-100 ml/beat
Factors affecting SV
- Preload
- Afterload
- Contractility
Normal CI
2.5-4 L/min/m^2
Normal HR
60-100 bpm
Normal ejection fraction
40-60%
CI formula
CI = CO/BSA
BSA = body surface area - Does not account for: Personal build (fat vs muscle) Diseases that alter metabolism Edema/Diuresis/Ascites (fluid in peritoneal cavity)
SV formula
SV = EDV - ESV
Variables affecting CO
- Metabolic rate / O2 demand -> BIGGEST
- Gender
- Body size (more CO if bigger)
- Age (highest in childhood and diminishes with age)
- Posture
Factors increasing metabolism
- Sepsis
- Strong emotion
- Major trauma
- Surgery
- Exercise
- Fever
Female vs Male
- Females 10% less CO than males in similar body mass
- Up to 45% higher if pregnant
Posture and CO
- CO decreases by 20% when standing vs supine
BSA
BSA = sqrt of [(cm x kg) / 3600]
CO equilibrium
- Pulmonary flow = Systemic flow
- Measurement from any point in CV system is representative
- ONLY if free of shunts/disease
PFO frequency
- 20-30%
- Hagen et all at Mayo
L to R shunting
- Overloads R ventricle
- Pulmonary flow > Systemic flow
- In ASD / VSD / PFO / acyanotic congenital anomalies
R to L shunting
- Systemic flow > Pulmonary flow
- In Tetralogy of Fallot (TOF) / Cyanotic congenital defects
Shunts and CO
- Shunts render all CO measurements invalid
- CO measurements assume equal flow in systemic/pulmonary
Regurgitant Heart Lesions
- Goes unmeasured
- Tricuspid/Pulmonary: recirculation of blood in R heart
- Mitral regurgitation: jetting contaminates blood at PA sample site
Most important hemodynamic measurement
- CO….BP not enough
- CO may decrease 33% with same measured BP
- CO < 50% of normal…… life threatening
- CO < 1 L/min/m2…..Death
Fick O2 consumption method
- Invasive
- CO = VO2 / A-V O2 difference
- Measures A-V sats and Oxygen uptake by lungs (3.5 ml/kg/min)
- Advantages: Most accurate when done right
Most accurate if CO is low
Good for regurgitant tricuspid/pulmonary valves - Disadvantages: Time consuming and meticulous
Multiple people
Stable patient
Hard to be repeatable
NOT VALID if shunts
Long wait for results
Least accurate if high CO